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[Lung disease and HIV infection in children at the Charles de Gaulle university pediatric hospital center in Ouagadougou (Burkina Faso)].
Sante. 2008 Jan-Mar; 18(1):15-8.S

Abstract

To compare the clinical and radiological aspects of lung diseases in HIV-positive and HIV-negative children, we conducted a retrospective case control study covering a 3-year period from January 2003 through December 2005 at Charles de Gaulle University Pediatric Hospital Center in Ouagadougou. HIV-positive patients hospitalised for lung disease were matched to HIV-negative patients controls, hospitalised for the same symptoms, by age and date of hospitalisation. The study included 186 patients (93 HIV-positive and 93 HIV-negative) and collected data on age, sex, clinical signs, radiological signs and short-term course. Of the 93 HIV-positive children suspected to have been contaminated by mother-to-child transmission, 92 had HIV1 and 1 had a double infection of HIV1 and 2. The mean age in both groups was 48 months. Clinically severe lung disease (44%) was more common in HIV-positive children. Radiology showed that interstitial syndrome was significantly more common in HIV-positive children (p=0001) with a sensitivity of 71% and a specificity of 60%. The case-fatality rate was 4.2% among HIV-positive children. This study allows us to remind paediatricians of the importance of lung disease in HIV-infected children. Moreover, the vertical transmission responsible for disease in all our patients shows the need to accelerate the scaling up of the program for prevention of mother-to-child HIV transmission in our country.

Links

Publisher Full Text
jle.com
john-libbey-eurotext.fr

Authors+Show Affiliations

Kouéta F
Unité de formation et de recherche en sciences de la santé (UFR/SDS), Université de Ouagadougou, Service de pédiatrie médicale du CHUP-CDG, BP 1198 BP 01, Ouagadougou 01 Burkina Faso. kouetafla@yahoo.com
Yé D
No affiliation info available
Dao L
No affiliation info available
Zoungrana-Kaboré A
No affiliation info available
Ouédraogo SA
No affiliation info available
Napon M
No affiliation info available
Sawadogo A
No affiliation info available

MeSH

Burkina FasoCase-Control StudiesChildChild, PreschoolFemaleHIV InfectionsHIV SeronegativityHIV SeropositivityHIV-1HIV-2HumansInfantInfant, NewbornInfectious Disease Transmission, VerticalLung DiseasesMalePregnancyPregnancy Complications, InfectiousRetrospective Studies

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

fre

PubMed ID

18684685

Citation

Kouéta, Fla, et al. "[Lung Disease and HIV Infection in Children at the Charles De Gaulle University Pediatric Hospital Center in Ouagadougou (Burkina Faso)]." Sante (Montrouge, France), vol. 18, no. 1, 2008, pp. 15-8.
Kouéta F, Yé D, Dao L, et al. [Lung disease and HIV infection in children at the Charles de Gaulle university pediatric hospital center in Ouagadougou (Burkina Faso)]. Sante. 2008;18(1):15-8.
Kouéta, F., Yé, D., Dao, L., Zoungrana-Kaboré, A., Ouédraogo, S. A., Napon, M., & Sawadogo, A. (2008). [Lung disease and HIV infection in children at the Charles de Gaulle university pediatric hospital center in Ouagadougou (Burkina Faso)]. Sante (Montrouge, France), 18(1), 15-8. https://doi.org/10.1684/san.2008.0099
Kouéta F, et al. [Lung Disease and HIV Infection in Children at the Charles De Gaulle University Pediatric Hospital Center in Ouagadougou (Burkina Faso)]. Sante. 2008 Jan-Mar;18(1):15-8. PubMed PMID: 18684685.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Lung disease and HIV infection in children at the Charles de Gaulle university pediatric hospital center in Ouagadougou (Burkina Faso)]. AU - Kouéta,Fla, AU - Yé,Diarra, AU - Dao,Lassina, AU - Zoungrana-Kaboré,Alice, AU - Ouédraogo,Sylvie Armelle P, AU - Napon,M, AU - Sawadogo,Alphonse, PY - 2008/8/8/pubmed PY - 2008/12/17/medline PY - 2008/8/8/entrez SP - 15 EP - 8 JF - Sante (Montrouge, France) JO - Sante VL - 18 IS - 1 N2 - To compare the clinical and radiological aspects of lung diseases in HIV-positive and HIV-negative children, we conducted a retrospective case control study covering a 3-year period from January 2003 through December 2005 at Charles de Gaulle University Pediatric Hospital Center in Ouagadougou. HIV-positive patients hospitalised for lung disease were matched to HIV-negative patients controls, hospitalised for the same symptoms, by age and date of hospitalisation. The study included 186 patients (93 HIV-positive and 93 HIV-negative) and collected data on age, sex, clinical signs, radiological signs and short-term course. Of the 93 HIV-positive children suspected to have been contaminated by mother-to-child transmission, 92 had HIV1 and 1 had a double infection of HIV1 and 2. The mean age in both groups was 48 months. Clinically severe lung disease (44%) was more common in HIV-positive children. Radiology showed that interstitial syndrome was significantly more common in HIV-positive children (p=0001) with a sensitivity of 71% and a specificity of 60%. The case-fatality rate was 4.2% among HIV-positive children. This study allows us to remind paediatricians of the importance of lung disease in HIV-infected children. Moreover, the vertical transmission responsible for disease in all our patients shows the need to accelerate the scaling up of the program for prevention of mother-to-child HIV transmission in our country. SN - 1157-5999 UR - https://www.unboundmedicine.com/medline/citation/18684685/[Lung_disease_and_HIV_infection_in_children_at_the_Charles_de_Gaulle_university_pediatric_hospital_center_in_Ouagadougou__Burkina_Faso_]_ L2 - http://www.jle.com/medline.md?issn=1157-5999&vol=18&iss=1&page=15 DB - PRIME DP - Unbound Medicine ER -