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Ten-year review of hospital admissions among children with sickle cell disease in Kuwait.
Med Princ Pract. 2008; 17(5):404-8.MP

Abstract

OBJECTIVE

This study was designed to document the common causes and patterns of hospitalization among sickle cell disease (SCD) patients in Kuwait.

SUBJECTS AND METHODS

The case files of all SCD patients admitted to the hospital between 1995 and 2004 were studied. Their personal data, hemoglobin genotype, diagnosis on admission, complete blood count, treatment received, length of stay and outcome were documented.

RESULTS

Fifty SCD patients aged from 10 months to 14.8 years (mean: 8.7 +/- 2.8 years) had 351 admissions over the 10-year period accounting for 0.6% of all admissions to the pediatric wards. The 50 patients were made up of 18 Hb SS, 28 S beta(0)thal and 4 Hb SD patients. Common causes of admission were vaso-occlusive crisis: 222 (63.2%), acute splenic sequestration crisis: 32 (9.1%), hemolytic crisis: 31 (8.8%) and acute chest syndrome: 23 (6.6%). Stroke was seen in only 1 patient, and bacteriologically proven (Salmonella) acute osteomyelitis in 1 patient. There were no deaths during the study period.

CONCLUSIONS

Vaso-occlusive crisis was the commonest cause of hospitalization among our SCD patients. Efforts should be intensified to give advice on preventive measures. The use of hydroxyurea should be encouraged in patients with frequent severe pain crises.

Authors+Show Affiliations

Department of Pediatrics, Mubarak Al-Kabeer Hospital, Kuwait University, Kuwait.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18685282

Citation

Akar, Najwa Ali, and Adekunle Adekile. "Ten-year Review of Hospital Admissions Among Children With Sickle Cell Disease in Kuwait." Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre, vol. 17, no. 5, 2008, pp. 404-8.
Akar NA, Adekile A. Ten-year review of hospital admissions among children with sickle cell disease in Kuwait. Med Princ Pract. 2008;17(5):404-8.
Akar, N. A., & Adekile, A. (2008). Ten-year review of hospital admissions among children with sickle cell disease in Kuwait. Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre, 17(5), 404-8. https://doi.org/10.1159/000141506
Akar NA, Adekile A. Ten-year Review of Hospital Admissions Among Children With Sickle Cell Disease in Kuwait. Med Princ Pract. 2008;17(5):404-8. PubMed PMID: 18685282.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ten-year review of hospital admissions among children with sickle cell disease in Kuwait. AU - Akar,Najwa Ali, AU - Adekile,Adekunle, Y1 - 2008/08/06/ PY - 2007/08/04/received PY - 2007/10/29/accepted PY - 2008/8/8/pubmed PY - 2009/1/1/medline PY - 2008/8/8/entrez SP - 404 EP - 8 JF - Medical principles and practice : international journal of the Kuwait University, Health Science Centre JO - Med Princ Pract VL - 17 IS - 5 N2 - OBJECTIVE: This study was designed to document the common causes and patterns of hospitalization among sickle cell disease (SCD) patients in Kuwait. SUBJECTS AND METHODS: The case files of all SCD patients admitted to the hospital between 1995 and 2004 were studied. Their personal data, hemoglobin genotype, diagnosis on admission, complete blood count, treatment received, length of stay and outcome were documented. RESULTS: Fifty SCD patients aged from 10 months to 14.8 years (mean: 8.7 +/- 2.8 years) had 351 admissions over the 10-year period accounting for 0.6% of all admissions to the pediatric wards. The 50 patients were made up of 18 Hb SS, 28 S beta(0)thal and 4 Hb SD patients. Common causes of admission were vaso-occlusive crisis: 222 (63.2%), acute splenic sequestration crisis: 32 (9.1%), hemolytic crisis: 31 (8.8%) and acute chest syndrome: 23 (6.6%). Stroke was seen in only 1 patient, and bacteriologically proven (Salmonella) acute osteomyelitis in 1 patient. There were no deaths during the study period. CONCLUSIONS: Vaso-occlusive crisis was the commonest cause of hospitalization among our SCD patients. Efforts should be intensified to give advice on preventive measures. The use of hydroxyurea should be encouraged in patients with frequent severe pain crises. SN - 1423-0151 UR - https://www.unboundmedicine.com/medline/citation/18685282/Ten_year_review_of_hospital_admissions_among_children_with_sickle_cell_disease_in_Kuwait_ L2 - https://www.karger.com?DOI=10.1159/000141506 DB - PRIME DP - Unbound Medicine ER -