Tags

Type your tag names separated by a space and hit enter

Dietary macronutrients, cholesterol, and sodium and lower urinary tract symptoms in men.
Eur Urol. 2009 May; 55(5):1179-89.EU

Abstract

BACKGROUND

Little is known about dietary correlates of lower urinary tract symptoms (LUTS).

OBJECTIVE

To examine associations between dietary intakes of total energy, carbohydrates, protein, fats, cholesterol, and sodium and LUTS in men.

DESIGN, SETTING, AND PARTICIPANTS

Cross-sectional study of 1545 men aged 30-79 yr in the Boston Area Community Health survey (2002-2005), a random population-based sample. Dietary data were assessed by validated self-administered food frequency questionnaire. LUTS and covariate data were collected during in-person interviews. Primary analyses used multivariate logistic regression.

MEASUREMENTS

Outcomes were moderate to severe LUTS, storage symptoms, and voiding symptoms as measured by the American Urological Association Symptom Index.

RESULTS AND LIMITATIONS

Greater total energy intake was associated with higher LUTS symptom score (p(trend)<0.01) and increased likelihood of storage symptoms. No associations were observed with total, saturated, or monounsaturated fat intake or carbohydrates. Men who consumed more protein were less likely to report LUTS, particularly voiding symptoms (quintile 5 vs quintile 1 OR=0.35; 95% CI, 0.17-0.74; p=0.006). Sodium intake had positive linear associations with LUTS (p(trend)=0.01) and storage symptom score (p(trend)=0.004); this finding should be confirmed by studies using biomarkers of sodium exposure. Storage symptoms increased slightly with greater polyunsaturated fat intake (p(trend)=0.006). Data on specific polyunsaturated fats were unavailable.

CONCLUSIONS

This community-based study of men found that total energy and sodium intake were positively associated with LUTS, whereas greater protein intake was inversely associated with LUTS.

Authors+Show Affiliations

New England Research Institutes, Watertown, MA 02472, USA. nmaserejian@neriscience.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

18692303

Citation

Maserejian, Nancy Nairi, et al. "Dietary Macronutrients, Cholesterol, and Sodium and Lower Urinary Tract Symptoms in Men." European Urology, vol. 55, no. 5, 2009, pp. 1179-89.
Maserejian NN, Giovannucci EL, McKinlay JB. Dietary macronutrients, cholesterol, and sodium and lower urinary tract symptoms in men. Eur Urol. 2009;55(5):1179-89.
Maserejian, N. N., Giovannucci, E. L., & McKinlay, J. B. (2009). Dietary macronutrients, cholesterol, and sodium and lower urinary tract symptoms in men. European Urology, 55(5), 1179-89. https://doi.org/10.1016/j.eururo.2008.07.058
Maserejian NN, Giovannucci EL, McKinlay JB. Dietary Macronutrients, Cholesterol, and Sodium and Lower Urinary Tract Symptoms in Men. Eur Urol. 2009;55(5):1179-89. PubMed PMID: 18692303.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary macronutrients, cholesterol, and sodium and lower urinary tract symptoms in men. AU - Maserejian,Nancy Nairi, AU - Giovannucci,Edward L, AU - McKinlay,John B, Y1 - 2008/08/03/ PY - 2008/03/13/received PY - 2008/07/25/accepted PY - 2008/8/12/pubmed PY - 2009/10/27/medline PY - 2008/8/12/entrez SP - 1179 EP - 89 JF - European urology JO - Eur Urol VL - 55 IS - 5 N2 - BACKGROUND: Little is known about dietary correlates of lower urinary tract symptoms (LUTS). OBJECTIVE: To examine associations between dietary intakes of total energy, carbohydrates, protein, fats, cholesterol, and sodium and LUTS in men. DESIGN, SETTING, AND PARTICIPANTS: Cross-sectional study of 1545 men aged 30-79 yr in the Boston Area Community Health survey (2002-2005), a random population-based sample. Dietary data were assessed by validated self-administered food frequency questionnaire. LUTS and covariate data were collected during in-person interviews. Primary analyses used multivariate logistic regression. MEASUREMENTS: Outcomes were moderate to severe LUTS, storage symptoms, and voiding symptoms as measured by the American Urological Association Symptom Index. RESULTS AND LIMITATIONS: Greater total energy intake was associated with higher LUTS symptom score (p(trend)<0.01) and increased likelihood of storage symptoms. No associations were observed with total, saturated, or monounsaturated fat intake or carbohydrates. Men who consumed more protein were less likely to report LUTS, particularly voiding symptoms (quintile 5 vs quintile 1 OR=0.35; 95% CI, 0.17-0.74; p=0.006). Sodium intake had positive linear associations with LUTS (p(trend)=0.01) and storage symptom score (p(trend)=0.004); this finding should be confirmed by studies using biomarkers of sodium exposure. Storage symptoms increased slightly with greater polyunsaturated fat intake (p(trend)=0.006). Data on specific polyunsaturated fats were unavailable. CONCLUSIONS: This community-based study of men found that total energy and sodium intake were positively associated with LUTS, whereas greater protein intake was inversely associated with LUTS. SN - 1873-7560 UR - https://www.unboundmedicine.com/medline/citation/18692303/Dietary_macronutrients_cholesterol_and_sodium_and_lower_urinary_tract_symptoms_in_men_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0302-2838(08)00915-9 DB - PRIME DP - Unbound Medicine ER -