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Endocannabinoids and the control of energy homeostasis.
J Biol Chem. 2008 Nov 28; 283(48):33021-5.JB

Abstract

Endocannabinoids (ECBs) are ubiquitous lipid mediators that act through the same G protein-coupled receptors (CB1 and CB2) that recognize plant-derived cannabinoids. As regulators of metabolism, ECBs are anabolic: they increase the intake, promote the storage, and decrease the expenditure of energy. Recent work indicates that activation of peripheral CB1 receptors by ECBs plays a key role in the hormonal/metabolic changes associated with obesity/metabolic syndrome and may be targeted for its pharmacotherapy.

Authors+Show Affiliations

Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892-9413, USA. gkunos@mail.nih.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

18694938

Citation

Kunos, George, et al. "Endocannabinoids and the Control of Energy Homeostasis." The Journal of Biological Chemistry, vol. 283, no. 48, 2008, pp. 33021-5.
Kunos G, Osei-Hyiaman D, Liu J, et al. Endocannabinoids and the control of energy homeostasis. J Biol Chem. 2008;283(48):33021-5.
Kunos, G., Osei-Hyiaman, D., Liu, J., Godlewski, G., & Bátkai, S. (2008). Endocannabinoids and the control of energy homeostasis. The Journal of Biological Chemistry, 283(48), 33021-5. https://doi.org/10.1074/jbc.R800012200
Kunos G, et al. Endocannabinoids and the Control of Energy Homeostasis. J Biol Chem. 2008 Nov 28;283(48):33021-5. PubMed PMID: 18694938.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endocannabinoids and the control of energy homeostasis. AU - Kunos,George, AU - Osei-Hyiaman,Douglas, AU - Liu,Jie, AU - Godlewski,Gregorz, AU - Bátkai,Sándor, Y1 - 2008/08/11/ PY - 2008/8/13/pubmed PY - 2009/1/30/medline PY - 2008/8/13/entrez SP - 33021 EP - 5 JF - The Journal of biological chemistry JO - J. Biol. Chem. VL - 283 IS - 48 N2 - Endocannabinoids (ECBs) are ubiquitous lipid mediators that act through the same G protein-coupled receptors (CB1 and CB2) that recognize plant-derived cannabinoids. As regulators of metabolism, ECBs are anabolic: they increase the intake, promote the storage, and decrease the expenditure of energy. Recent work indicates that activation of peripheral CB1 receptors by ECBs plays a key role in the hormonal/metabolic changes associated with obesity/metabolic syndrome and may be targeted for its pharmacotherapy. SN - 0021-9258 UR - https://www.unboundmedicine.com/medline/citation/18694938/Endocannabinoids_and_the_control_of_energy_homeostasis_ L2 - http://www.jbc.org/cgi/pmidlookup?view=long&pmid=18694938 DB - PRIME DP - Unbound Medicine ER -