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Optical coherence tomography findings for nanophthalmic eyes.
Retina. 2008 Jul-Aug; 28(7):1002-7.R

Abstract

PURPOSE

To describe the optical coherence tomography (OCT) findings for nanophthalmic eyes.

METHODS

: In this retrospective, single-center, observational case series, 15 patients (28 eyes) with axial lengths of <or=20.5 mm were included. Ultrasonography (A- and B-scans), keratometry, and OCT were performed. The main outcome measures were average foveal thickness, foveal center point thickness, total macular volume, and a new quantitative measure of foveal depression, relative foveal depression (RFD). Reference values for RFD were obtained by examining 57 healthy eyes with axial lengths of 21.5 mm to 27 mm.

RESULTS

The foveae of nanophthalmic eyes had diminished foveal depression due to thickened outer retinal layers. One patient with papillomacular folds was identified as having posterior microphthalmos. There was a good correlation between axial length on one hand and foveal thickness, foveal center point thickness, macula volume, and RFD on the other hand (r = -0.58, -0.61, -0.56, and -0.70 with P = 0.003, 0.001, 0.004, and 0.000, respectively). The average RFD for eyes with normal axial lengths was 0.43.

CONCLUSIONS

OCT findings for nanophthalmic eyes with foveal underdevelopment are different from posterior microphthalmos and foveal hypoplasia seen in other disorders. The new measure RFD is a useful tool in ocular tomography.

Authors+Show Affiliations

Department of Ophthalmology, University Medical Center Utrecht, Utrecht, The Netherlands. w.r.bijlsma@umcutrecht.nlNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18698304

Citation

Bijlsma, Ward R., et al. "Optical Coherence Tomography Findings for Nanophthalmic Eyes." Retina (Philadelphia, Pa.), vol. 28, no. 7, 2008, pp. 1002-7.
Bijlsma WR, van Schooneveld MJ, Van der Lelij A. Optical coherence tomography findings for nanophthalmic eyes. Retina. 2008;28(7):1002-7.
Bijlsma, W. R., van Schooneveld, M. J., & Van der Lelij, A. (2008). Optical coherence tomography findings for nanophthalmic eyes. Retina (Philadelphia, Pa.), 28(7), 1002-7. https://doi.org/10.1097/IAE.0b013e31816d400c
Bijlsma WR, van Schooneveld MJ, Van der Lelij A. Optical Coherence Tomography Findings for Nanophthalmic Eyes. Retina. 2008 Jul-Aug;28(7):1002-7. PubMed PMID: 18698304.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Optical coherence tomography findings for nanophthalmic eyes. AU - Bijlsma,Ward R, AU - van Schooneveld,Mary J, AU - Van der Lelij,Allegonda, PY - 2008/8/14/pubmed PY - 2008/8/30/medline PY - 2008/8/14/entrez SP - 1002 EP - 7 JF - Retina (Philadelphia, Pa.) JO - Retina VL - 28 IS - 7 N2 - PURPOSE: To describe the optical coherence tomography (OCT) findings for nanophthalmic eyes. METHODS: : In this retrospective, single-center, observational case series, 15 patients (28 eyes) with axial lengths of <or=20.5 mm were included. Ultrasonography (A- and B-scans), keratometry, and OCT were performed. The main outcome measures were average foveal thickness, foveal center point thickness, total macular volume, and a new quantitative measure of foveal depression, relative foveal depression (RFD). Reference values for RFD were obtained by examining 57 healthy eyes with axial lengths of 21.5 mm to 27 mm. RESULTS: The foveae of nanophthalmic eyes had diminished foveal depression due to thickened outer retinal layers. One patient with papillomacular folds was identified as having posterior microphthalmos. There was a good correlation between axial length on one hand and foveal thickness, foveal center point thickness, macula volume, and RFD on the other hand (r = -0.58, -0.61, -0.56, and -0.70 with P = 0.003, 0.001, 0.004, and 0.000, respectively). The average RFD for eyes with normal axial lengths was 0.43. CONCLUSIONS: OCT findings for nanophthalmic eyes with foveal underdevelopment are different from posterior microphthalmos and foveal hypoplasia seen in other disorders. The new measure RFD is a useful tool in ocular tomography. SN - 0275-004X UR - https://www.unboundmedicine.com/medline/citation/18698304/Optical_coherence_tomography_findings_for_nanophthalmic_eyes_ L2 - https://doi.org/10.1097/IAE.0b013e31816d400c DB - PRIME DP - Unbound Medicine ER -