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Acute generalized exanthematous pustulosis after pemetrexed, and recurrence after re-introduction.
Clin Exp Dermatol. 2009 Apr; 34(3):337-9.CE

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous reaction, which in most cases, is related to medication. Pemetrexed is an antifolate drug, approved for treatment of metastatic non-small-cell lung cancer (NSCLC) and malignant pleural mesothelioma (MPM). We present a case of AGEP caused by pemetrexed, and a recurrence of this eruption after re-introduction of pemetrexed despite use of corticosteroids.

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Authors+Show Affiliations

Bracke A
University Hospital Antwerp, Antwerp, Belgium. annick.bracke@uza.be
Van Marck E
No affiliation info available
Lambert J
No affiliation info available

MeSH

Acute DiseaseAntimetabolites, AntineoplasticDrug EruptionsExanthemaGlutamatesGuanineHumansMaleMiddle AgedPemetrexedSkin Diseases, Vesiculobullous

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

18699838

Citation

Bracke, A, et al. "Acute Generalized Exanthematous Pustulosis After Pemetrexed, and Recurrence After Re-introduction." Clinical and Experimental Dermatology, vol. 34, no. 3, 2009, pp. 337-9.
Bracke A, Van Marck E, Lambert J. Acute generalized exanthematous pustulosis after pemetrexed, and recurrence after re-introduction. Clin Exp Dermatol. 2009;34(3):337-9.
Bracke, A., Van Marck, E., & Lambert, J. (2009). Acute generalized exanthematous pustulosis after pemetrexed, and recurrence after re-introduction. Clinical and Experimental Dermatology, 34(3), 337-9. https://doi.org/10.1111/j.1365-2230.2008.02902.x
Bracke A, Van Marck E, Lambert J. Acute Generalized Exanthematous Pustulosis After Pemetrexed, and Recurrence After Re-introduction. Clin Exp Dermatol. 2009;34(3):337-9. PubMed PMID: 18699838.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute generalized exanthematous pustulosis after pemetrexed, and recurrence after re-introduction. AU - Bracke,A, AU - Van Marck,E, AU - Lambert,J, Y1 - 2008/08/09/ PY - 2008/8/14/pubmed PY - 2009/4/25/medline PY - 2008/8/14/entrez SP - 337 EP - 9 JF - Clinical and experimental dermatology JO - Clin Exp Dermatol VL - 34 IS - 3 N2 - Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous reaction, which in most cases, is related to medication. Pemetrexed is an antifolate drug, approved for treatment of metastatic non-small-cell lung cancer (NSCLC) and malignant pleural mesothelioma (MPM). We present a case of AGEP caused by pemetrexed, and a recurrence of this eruption after re-introduction of pemetrexed despite use of corticosteroids. SN - 1365-2230 UR - https://www.unboundmedicine.com/medline/citation/18699838/Acute_generalized_exanthematous_pustulosis_after_pemetrexed_and_recurrence_after_re_introduction_ L2 - https://doi.org/10.1111/j.1365-2230.2008.02902.x DB - PRIME DP - Unbound Medicine ER -