Tags

Type your tag names separated by a space and hit enter

Causative agents and antimicrobial susceptibilities of urinary tract infections in the northwest of Iran.
Int J Infect Dis. 2009 Mar; 13(2):140-4.IJ

Abstract

BACKGROUND

The empirical therapy of urinary tract infections (UTI) relies on the predictability of the agents causing UTI and knowledge of their antimicrobial susceptibility patterns.

METHODS

In a prospective study undertaken over a 14-month period, 5136 samples from patients suspected of having a UTI were analyzed, of which 676 were culture-positive. Isolated bacteria were identified by standard tests, and antibiotic susceptibility was determined by disk diffusion method.

RESULTS

According to our results, Escherichia coli was the most common etiological agent of UTI (74.6%), followed by Klebsiella spp (11.7%), Staphylococcus saprophyticus (6.4%), and Pseudomonas aeruginosa (2.2%). Analysis of the frequency of isolated bacteria according to the age of the patients revealed that Klebsiella infections are more prevalent in the older age groups (>10 years) and Pseudomonas infections are more prevalent in children and the elderly (<9 years and >60 years). Results of antimicrobial susceptibility analysis for E. coli, as the most prevalent cause of UTI, to commonly used antibiotics are as follows: amikacin (97.8%), gentamicin (97%), ciprofloxacin (94%), nitrofurantoin (87.1%), nalidixic acid (93.7%), trimethoprim-sulfamethoxazole (48.2%), cephalexin (76%), and ampicillin (6.9%).

CONCLUSIONS

The results show that the antimicrobial resistance patterns of the causes of UTI are highly variable and continuous surveillance of trends in resistance patterns of uropathogens is important.

Authors+Show Affiliations

Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18703368

Citation

Farajnia, Safar, et al. "Causative Agents and Antimicrobial Susceptibilities of Urinary Tract Infections in the Northwest of Iran." International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases, vol. 13, no. 2, 2009, pp. 140-4.
Farajnia S, Alikhani MY, Ghotaslou R, et al. Causative agents and antimicrobial susceptibilities of urinary tract infections in the northwest of Iran. Int J Infect Dis. 2009;13(2):140-4.
Farajnia, S., Alikhani, M. Y., Ghotaslou, R., Naghili, B., & Nakhlband, A. (2009). Causative agents and antimicrobial susceptibilities of urinary tract infections in the northwest of Iran. International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases, 13(2), 140-4. https://doi.org/10.1016/j.ijid.2008.04.014
Farajnia S, et al. Causative Agents and Antimicrobial Susceptibilities of Urinary Tract Infections in the Northwest of Iran. Int J Infect Dis. 2009;13(2):140-4. PubMed PMID: 18703368.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Causative agents and antimicrobial susceptibilities of urinary tract infections in the northwest of Iran. AU - Farajnia,Safar, AU - Alikhani,Mohammad Yousef, AU - Ghotaslou,Reza, AU - Naghili,Behrooz, AU - Nakhlband,Ailar, Y1 - 2008/08/13/ PY - 2007/12/12/received PY - 2008/03/15/revised PY - 2008/04/23/accepted PY - 2008/8/16/pubmed PY - 2009/6/3/medline PY - 2008/8/16/entrez SP - 140 EP - 4 JF - International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases JO - Int J Infect Dis VL - 13 IS - 2 N2 - BACKGROUND: The empirical therapy of urinary tract infections (UTI) relies on the predictability of the agents causing UTI and knowledge of their antimicrobial susceptibility patterns. METHODS: In a prospective study undertaken over a 14-month period, 5136 samples from patients suspected of having a UTI were analyzed, of which 676 were culture-positive. Isolated bacteria were identified by standard tests, and antibiotic susceptibility was determined by disk diffusion method. RESULTS: According to our results, Escherichia coli was the most common etiological agent of UTI (74.6%), followed by Klebsiella spp (11.7%), Staphylococcus saprophyticus (6.4%), and Pseudomonas aeruginosa (2.2%). Analysis of the frequency of isolated bacteria according to the age of the patients revealed that Klebsiella infections are more prevalent in the older age groups (>10 years) and Pseudomonas infections are more prevalent in children and the elderly (<9 years and >60 years). Results of antimicrobial susceptibility analysis for E. coli, as the most prevalent cause of UTI, to commonly used antibiotics are as follows: amikacin (97.8%), gentamicin (97%), ciprofloxacin (94%), nitrofurantoin (87.1%), nalidixic acid (93.7%), trimethoprim-sulfamethoxazole (48.2%), cephalexin (76%), and ampicillin (6.9%). CONCLUSIONS: The results show that the antimicrobial resistance patterns of the causes of UTI are highly variable and continuous surveillance of trends in resistance patterns of uropathogens is important. SN - 1878-3511 UR - https://www.unboundmedicine.com/medline/citation/18703368/Causative_agents_and_antimicrobial_susceptibilities_of_urinary_tract_infections_in_the_northwest_of_Iran_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1201-9712(08)01376-3 DB - PRIME DP - Unbound Medicine ER -