Tags

Type your tag names separated by a space and hit enter

Coffee consumption and risk of coronary heart diseases: a meta-analysis of 21 prospective cohort studies.
Int J Cardiol. 2009 Nov 12; 137(3):216-25.IJ

Abstract

BACKGROUND

A large amount of cohort studies addressed coffee consumption and risk of coronary heart disease (CHD) and yielded inconsistent results. We conducted a meta-analysis to estimate the pooling effects.

METHODS

We searched for all published English articles indexed in MEDLINE or PubMed from January 1966 to January 2008. Twenty-one independent prospective cohort studies, which tested CHD risk by coffee consumption, were identified. A general variance-based method was used to pool the relative risks (RR). 15,599 cases from 407,806 participants were included in pooling the overall effects.

RESULTS

As compared to the light coffee consumption (<1 cup/d in US or <or=2 cups/d in Europe), under the random-effects model, the pooled CHD RRs (95% CI) for all studies combined were 0.96 (0.87-1.06), 1.04 (0.92-1.17) and 1.07 (0.87-1.32) for the moderate (1-3 or 3-4 cups/d), heavy (4-5 or 5-6 cups/d) and very heavy (>or=6 or >or=7 cups/d) categories of coffee consumption (all p>0.05); Moderate coffee consumption showed significantly lower CHD RR (95% CI) of 0.82 (0.73-0.92) (p<0.001) in women, and of 0.87 (0.80-0.86) (p=0.001) in men and women followed <or=10 years.

CONCLUSION

Our findings do not support the hypothesis that coffee consumption increases the long-term risk of coronary heart disease. Habitual moderate coffee drinking was associated with a lower risk of CHD in women.

Authors+Show Affiliations

Department of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18707777

Citation

Wu, Jiang-nan, et al. "Coffee Consumption and Risk of Coronary Heart Diseases: a Meta-analysis of 21 Prospective Cohort Studies." International Journal of Cardiology, vol. 137, no. 3, 2009, pp. 216-25.
Wu JN, Ho SC, Zhou C, et al. Coffee consumption and risk of coronary heart diseases: a meta-analysis of 21 prospective cohort studies. Int J Cardiol. 2009;137(3):216-25.
Wu, J. N., Ho, S. C., Zhou, C., Ling, W. H., Chen, W. Q., Wang, C. L., & Chen, Y. M. (2009). Coffee consumption and risk of coronary heart diseases: a meta-analysis of 21 prospective cohort studies. International Journal of Cardiology, 137(3), 216-25. https://doi.org/10.1016/j.ijcard.2008.06.051
Wu JN, et al. Coffee Consumption and Risk of Coronary Heart Diseases: a Meta-analysis of 21 Prospective Cohort Studies. Int J Cardiol. 2009 Nov 12;137(3):216-25. PubMed PMID: 18707777.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Coffee consumption and risk of coronary heart diseases: a meta-analysis of 21 prospective cohort studies. AU - Wu,Jiang-nan, AU - Ho,Suzanne C, AU - Zhou,Chun, AU - Ling,Wen-hua, AU - Chen,Wei-qing, AU - Wang,Cui-ling, AU - Chen,Yu-ming, Y1 - 2008/08/15/ PY - 2007/11/23/received PY - 2008/03/23/revised PY - 2008/06/28/accepted PY - 2008/8/19/pubmed PY - 2010/2/27/medline PY - 2008/8/19/entrez SP - 216 EP - 25 JF - International journal of cardiology JO - Int. J. Cardiol. VL - 137 IS - 3 N2 - BACKGROUND: A large amount of cohort studies addressed coffee consumption and risk of coronary heart disease (CHD) and yielded inconsistent results. We conducted a meta-analysis to estimate the pooling effects. METHODS: We searched for all published English articles indexed in MEDLINE or PubMed from January 1966 to January 2008. Twenty-one independent prospective cohort studies, which tested CHD risk by coffee consumption, were identified. A general variance-based method was used to pool the relative risks (RR). 15,599 cases from 407,806 participants were included in pooling the overall effects. RESULTS: As compared to the light coffee consumption (<1 cup/d in US or <or=2 cups/d in Europe), under the random-effects model, the pooled CHD RRs (95% CI) for all studies combined were 0.96 (0.87-1.06), 1.04 (0.92-1.17) and 1.07 (0.87-1.32) for the moderate (1-3 or 3-4 cups/d), heavy (4-5 or 5-6 cups/d) and very heavy (>or=6 or >or=7 cups/d) categories of coffee consumption (all p>0.05); Moderate coffee consumption showed significantly lower CHD RR (95% CI) of 0.82 (0.73-0.92) (p<0.001) in women, and of 0.87 (0.80-0.86) (p=0.001) in men and women followed <or=10 years. CONCLUSION: Our findings do not support the hypothesis that coffee consumption increases the long-term risk of coronary heart disease. Habitual moderate coffee drinking was associated with a lower risk of CHD in women. SN - 1874-1754 UR - https://www.unboundmedicine.com/medline/citation/18707777/Coffee_consumption_and_risk_of_coronary_heart_diseases:_a_meta_analysis_of_21_prospective_cohort_studies_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0167-5273(08)00849-8 DB - PRIME DP - Unbound Medicine ER -