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Seroprevalence of human T-lymphotropic virus type 1 and 2 in Korean blood donors.
J Med Virol. 2008 Oct; 80(10):1864-7.JM

Abstract

The seroprevalence rate of human T-lymphotropic virus (HTLV) among the Korean blood donor population was studied to determine whether screening for HTLV should be implemented. A total of 15,173 serum samples collected from June to July 2006 at five Blood Centers which are located closely to Japan geographically, where the prevalence of HTLV is known to be high, were tested. Serological screening was done by a chemiluminescence method. Samples reactive repeatedly on serological screening were confirmed further by Western blot, line immunoassay, nested polymerase chain reaction and sequencing of proviral DNA. Six samples tested reactive with the serological assay showing a reactive rate of 0.004%. Among the six samples, one sample was confirmed as HTLV-1 positive, giving a confirmed reactive rate of 0.007%. Based on the results of this study, an extended study will be conducted to evaluate whether introduction of HTLV screening is necessary in Korea.

Authors+Show Affiliations

Blood Transfusion Research Institute, Korean Red Cross, Seoul, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18712809

Citation

Kwon, So-Yong, et al. "Seroprevalence of Human T-lymphotropic Virus Type 1 and 2 in Korean Blood Donors." Journal of Medical Virology, vol. 80, no. 10, 2008, pp. 1864-7.
Kwon SY, Lim AH, Park JY, et al. Seroprevalence of human T-lymphotropic virus type 1 and 2 in Korean blood donors. J Med Virol. 2008;80(10):1864-7.
Kwon, S. Y., Lim, A. H., Park, J. Y., Han, S. H., & Cho, N. S. (2008). Seroprevalence of human T-lymphotropic virus type 1 and 2 in Korean blood donors. Journal of Medical Virology, 80(10), 1864-7. https://doi.org/10.1002/jmv.21260
Kwon SY, et al. Seroprevalence of Human T-lymphotropic Virus Type 1 and 2 in Korean Blood Donors. J Med Virol. 2008;80(10):1864-7. PubMed PMID: 18712809.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Seroprevalence of human T-lymphotropic virus type 1 and 2 in Korean blood donors. AU - Kwon,So-Yong, AU - Lim,A Hyun, AU - Park,Ji Young, AU - Han,Seung Hee, AU - Cho,Nam-Sun, PY - 2008/8/21/pubmed PY - 2008/10/31/medline PY - 2008/8/21/entrez SP - 1864 EP - 7 JF - Journal of medical virology JO - J Med Virol VL - 80 IS - 10 N2 - The seroprevalence rate of human T-lymphotropic virus (HTLV) among the Korean blood donor population was studied to determine whether screening for HTLV should be implemented. A total of 15,173 serum samples collected from June to July 2006 at five Blood Centers which are located closely to Japan geographically, where the prevalence of HTLV is known to be high, were tested. Serological screening was done by a chemiluminescence method. Samples reactive repeatedly on serological screening were confirmed further by Western blot, line immunoassay, nested polymerase chain reaction and sequencing of proviral DNA. Six samples tested reactive with the serological assay showing a reactive rate of 0.004%. Among the six samples, one sample was confirmed as HTLV-1 positive, giving a confirmed reactive rate of 0.007%. Based on the results of this study, an extended study will be conducted to evaluate whether introduction of HTLV screening is necessary in Korea. SN - 1096-9071 UR - https://www.unboundmedicine.com/medline/citation/18712809/Seroprevalence_of_human_T_lymphotropic_virus_type_1_and_2_in_Korean_blood_donors_ L2 - https://doi.org/10.1002/jmv.21260 DB - PRIME DP - Unbound Medicine ER -