Tags

Type your tag names separated by a space and hit enter

Non-convulsive status epilepticus; the rate of occurrence in a general hospital.
Seizure. 2009 Jan; 18(1):38-42.S

Abstract

BACKGROUND

Non-convulsive status epilepticus (NCSE) has been increasingly recognized as a cause of impaired level of consciousness in the ICU and emergency rooms. The diagnosis can be easily missed without an electroencephalogram (EEG) given the paucity of overt clinical signs in this condition. Recently few published data estimated the prevalence to be between 3% and 8%.

OBJECTIVE

To assess the rate of occurrence of NCSE among patients with various degrees of impaired consciousness referred to the Neurophysiology Laboratory at Vancouver General Hospital.

METHOD

We conducted a retrospective analysis of 451 adult patients (>16 years of age) with a question of NCSE or with an unknown cause of impaired level of consciousness between the years 2002 and 2004. NCSE was defined according to the Young's criteria of electrographic status epilepticus. NCSE was categorized into focal and generalized epileptic activity based on the continuous EEG monitoring (CEEG). Further analysis of age, gender and etiology was performed.

RESULTS

Of 451 patients, EEG demonstrated electrographic status epilepticus with no overt clinical signs in 42 patients (9.3%). Median age was 61.8 years (range 21-94). According to etiology, 38.1% of patients with NCSE had hypoxic-anoxic injury, 19% had intracerebral hemorrhage (including trauma), 11.9% had the diagnosis of idiopathic or cryptogenic epilepsy, 7.1% had ischemic stroke, 4.8% were secondary to tumors and 4.8% to viral encephalitis.

CONCLUSION

The rate of occurrence of NCSE in patients with decreased level of consciousness was 9.3%. The cohort represented a group of patients who were comatose and required assisted ventilation or had altered level of consciousness. Hypoxic brain injury was the most responsible etiology of NCSE in the cohort studied.

Links

Aggregator Full Text
Publisher Full Text
linkinghub.elsevier.com
linkinghub.elsevier.com

Authors+Show Affiliations

Alroughani R
Neurophysiology Department and the Epilepsy Program, Vancouver General Hospital, Division of Neurology, University of British Columbia, Vancouver, Canada.
Javidan M
No affiliation info available
Qasem A
No affiliation info available
Alotaibi N
No affiliation info available

MeSH

AdultAgedAged, 80 and overCohort StudiesConsciousnessElectroencephalographyFemaleHospitals, GeneralHumansMaleMiddle AgedRetrospective StudiesStatus EpilepticusYoung Adult

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18755608

Citation

Alroughani, R, et al. "Non-convulsive Status Epilepticus; the Rate of Occurrence in a General Hospital." Seizure, vol. 18, no. 1, 2009, pp. 38-42.
Alroughani R, Javidan M, Qasem A, et al. Non-convulsive status epilepticus; the rate of occurrence in a general hospital. Seizure. 2009;18(1):38-42.
Alroughani, R., Javidan, M., Qasem, A., & Alotaibi, N. (2009). Non-convulsive status epilepticus; the rate of occurrence in a general hospital. Seizure, 18(1), 38-42. https://doi.org/10.1016/j.seizure.2008.06.013
Alroughani R, et al. Non-convulsive Status Epilepticus; the Rate of Occurrence in a General Hospital. Seizure. 2009;18(1):38-42. PubMed PMID: 18755608.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Non-convulsive status epilepticus; the rate of occurrence in a general hospital. AU - Alroughani,R, AU - Javidan,M, AU - Qasem,A, AU - Alotaibi,N, Y1 - 2008/08/27/ PY - 2007/11/17/received PY - 2008/04/30/revised PY - 2008/06/13/accepted PY - 2008/8/30/pubmed PY - 2009/4/1/medline PY - 2008/8/30/entrez SP - 38 EP - 42 JF - Seizure JO - Seizure VL - 18 IS - 1 N2 - BACKGROUND: Non-convulsive status epilepticus (NCSE) has been increasingly recognized as a cause of impaired level of consciousness in the ICU and emergency rooms. The diagnosis can be easily missed without an electroencephalogram (EEG) given the paucity of overt clinical signs in this condition. Recently few published data estimated the prevalence to be between 3% and 8%. OBJECTIVE: To assess the rate of occurrence of NCSE among patients with various degrees of impaired consciousness referred to the Neurophysiology Laboratory at Vancouver General Hospital. METHOD: We conducted a retrospective analysis of 451 adult patients (>16 years of age) with a question of NCSE or with an unknown cause of impaired level of consciousness between the years 2002 and 2004. NCSE was defined according to the Young's criteria of electrographic status epilepticus. NCSE was categorized into focal and generalized epileptic activity based on the continuous EEG monitoring (CEEG). Further analysis of age, gender and etiology was performed. RESULTS: Of 451 patients, EEG demonstrated electrographic status epilepticus with no overt clinical signs in 42 patients (9.3%). Median age was 61.8 years (range 21-94). According to etiology, 38.1% of patients with NCSE had hypoxic-anoxic injury, 19% had intracerebral hemorrhage (including trauma), 11.9% had the diagnosis of idiopathic or cryptogenic epilepsy, 7.1% had ischemic stroke, 4.8% were secondary to tumors and 4.8% to viral encephalitis. CONCLUSION: The rate of occurrence of NCSE in patients with decreased level of consciousness was 9.3%. The cohort represented a group of patients who were comatose and required assisted ventilation or had altered level of consciousness. Hypoxic brain injury was the most responsible etiology of NCSE in the cohort studied. SN - 1059-1311 UR - https://www.unboundmedicine.com/medline/citation/18755608/Non_convulsive_status_epilepticus L2 - https://linkinghub.elsevier.com/retrieve/pii/S1059-1311(08)00132-5 DB - PRIME DP - Unbound Medicine ER -