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Does diagnosis of metabolic syndrome predict the likelihood of peripheral arterial disease as defined by a low ankle-brachial index?
Eur J Cardiovasc Prev Rehabil. 2008 Dec; 15(6):693-7.EJ

Abstract

BACKGROUND

There is limited information about whether a diagnosis of metabolic syndrome (MS) predicts peripheral arterial disease independently of diabetes. This study assessed whether MS adds prognostic information beyond that relating to diabetes in the identification of a low ankle-brachial index (ABI).

DESIGN

Cross-sectional population-based study of people aged 50-75 years.

METHODS

Eight hundred and fifty-eight participants were randomly selected. The likelihood of low ABI (<0.90) was calculated according to MS status before and after excluding diabetes. The National Cholesterol Education Panel and the International Diabetes Federation (IDF) definitions of MS were used.

RESULTS

The prevalence of National Cholesterol Education Panel-defined and IDF-defined MS, and low ABI was 57.8, 61.1 and 7.5%, respectively. When there were participants with three or more criteria for MS, participants with only three criteria, and participants with four or five criteria were compared with participants without MS, the odds ratio for low ABI was 1.89 (95% confidence interval, 1.08-3.30), 1.34 (0.70-2.60) and 2.70 (1.45-5.03), respectively. The association of MS and low ABI lost statistical significance after excluding diabetes. No difference was observed using the IDF definition of MS.

CONCLUSION

Screening of participants with MS does not improve the identification of abnormal ABI provided by diabetes.

Authors+Show Affiliations

Internal Medicine Department, Virgen del Camino Hospital, Sanlúcar de Barrameda Cádiz, Spain. a.lopez.ssl@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18756176

Citation

López-Suárez, Alejandro, et al. "Does Diagnosis of Metabolic Syndrome Predict the Likelihood of Peripheral Arterial Disease as Defined By a Low Ankle-brachial Index?" European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups On Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, vol. 15, no. 6, 2008, pp. 693-7.
López-Suárez A, Beltrán-Robles M, Elvira-González J, et al. Does diagnosis of metabolic syndrome predict the likelihood of peripheral arterial disease as defined by a low ankle-brachial index? Eur J Cardiovasc Prev Rehabil. 2008;15(6):693-7.
López-Suárez, A., Beltrán-Robles, M., Elvira-González, J., Alwakil, M., Bascuñana-Quirell, A., Rosal-Obrador, J., Badani-Gutiérrez, H., Oliver-Pece, M., Pons-Raga, A., Ruiz-DeCastroviejo, J., Cañas-Hormigo, F., & Benítez-Rodríguez, E. (2008). Does diagnosis of metabolic syndrome predict the likelihood of peripheral arterial disease as defined by a low ankle-brachial index? European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups On Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 15(6), 693-7. https://doi.org/10.1097/HJR.0b013e32830c1cc5
López-Suárez A, et al. Does Diagnosis of Metabolic Syndrome Predict the Likelihood of Peripheral Arterial Disease as Defined By a Low Ankle-brachial Index. Eur J Cardiovasc Prev Rehabil. 2008;15(6):693-7. PubMed PMID: 18756176.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Does diagnosis of metabolic syndrome predict the likelihood of peripheral arterial disease as defined by a low ankle-brachial index? AU - López-Suárez,Alejandro, AU - Beltrán-Robles,Manuel, AU - Elvira-González,Javier, AU - Alwakil,Michael, AU - Bascuñana-Quirell,Antonio, AU - Rosal-Obrador,Joan, AU - Badani-Gutiérrez,Hugo, AU - Oliver-Pece,Miguel, AU - Pons-Raga,Amparo, AU - Ruiz-DeCastroviejo,Juan, AU - Cañas-Hormigo,Francisco, AU - Benítez-Rodríguez,Encarnación, PY - 2008/8/30/pubmed PY - 2009/4/21/medline PY - 2008/8/30/entrez SP - 693 EP - 7 JF - European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology JO - Eur J Cardiovasc Prev Rehabil VL - 15 IS - 6 N2 - BACKGROUND: There is limited information about whether a diagnosis of metabolic syndrome (MS) predicts peripheral arterial disease independently of diabetes. This study assessed whether MS adds prognostic information beyond that relating to diabetes in the identification of a low ankle-brachial index (ABI). DESIGN: Cross-sectional population-based study of people aged 50-75 years. METHODS: Eight hundred and fifty-eight participants were randomly selected. The likelihood of low ABI (<0.90) was calculated according to MS status before and after excluding diabetes. The National Cholesterol Education Panel and the International Diabetes Federation (IDF) definitions of MS were used. RESULTS: The prevalence of National Cholesterol Education Panel-defined and IDF-defined MS, and low ABI was 57.8, 61.1 and 7.5%, respectively. When there were participants with three or more criteria for MS, participants with only three criteria, and participants with four or five criteria were compared with participants without MS, the odds ratio for low ABI was 1.89 (95% confidence interval, 1.08-3.30), 1.34 (0.70-2.60) and 2.70 (1.45-5.03), respectively. The association of MS and low ABI lost statistical significance after excluding diabetes. No difference was observed using the IDF definition of MS. CONCLUSION: Screening of participants with MS does not improve the identification of abnormal ABI provided by diabetes. SN - 1741-8275 UR - https://www.unboundmedicine.com/medline/citation/18756176/Does_diagnosis_of_metabolic_syndrome_predict_the_likelihood_of_peripheral_arterial_disease_as_defined_by_a_low_ankle_brachial_index L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=linkout&amp;SEARCH=18756176.ui DB - PRIME DP - Unbound Medicine ER -