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Free radical scavenging and anti-inflammatory properties of Lagerstroemia speciosa (L).
Inflammopharmacology. 2008 Aug; 16(4):182-7.I

Abstract

The in vitro antioxidant activity of the successive extracts (ethyl acetate, ethanol, methanol and water) of the leaves of Lagerstroemia speciosa L. (Lythraceae) were studied by examining their superoxide, hydroxyl ion scavenging and by measuring lipid peroxidation. The ethyl acetate and ethanol extracts were found to possess greater antioxidant property than the methanol and water extracts. Anti-inflammatory activity of the ethyl acetate and ethanol extracts were examined using the carrageenan-induced acute inflammation and formalin-induced (chronic) paw edema models. In acute and chronic inflammation models, the ethyl acetate extract reduced the paw edema significantly in a dose-dependent manner. Whereas, ethanol extract did not show dose-dependent activity. This results suggests that the anti-inflammatory activity is possibly attributed to its free radical scavenging activity. It was found that ethyl acetate extract reduced the inflammation more significantly than the ethanol extract.

Authors+Show Affiliations

Amala Cancer Research Centre, Amala Nagar, Thrissur, 680 555 Kerala, India. priyasabu@rediffmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18759076

Citation

Priya, T T., et al. "Free Radical Scavenging and Anti-inflammatory Properties of Lagerstroemia Speciosa (L)." Inflammopharmacology, vol. 16, no. 4, 2008, pp. 182-7.
Priya TT, Sabu MC, Jolly CI. Free radical scavenging and anti-inflammatory properties of Lagerstroemia speciosa (L). Inflammopharmacology. 2008;16(4):182-7.
Priya, T. T., Sabu, M. C., & Jolly, C. I. (2008). Free radical scavenging and anti-inflammatory properties of Lagerstroemia speciosa (L). Inflammopharmacology, 16(4), 182-7. https://doi.org/10.1007/s10787-008-7002-6
Priya TT, Sabu MC, Jolly CI. Free Radical Scavenging and Anti-inflammatory Properties of Lagerstroemia Speciosa (L). Inflammopharmacology. 2008;16(4):182-7. PubMed PMID: 18759076.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Free radical scavenging and anti-inflammatory properties of Lagerstroemia speciosa (L). AU - Priya,T T, AU - Sabu,M C, AU - Jolly,C I, PY - 2008/9/2/pubmed PY - 2008/10/11/medline PY - 2008/9/2/entrez SP - 182 EP - 7 JF - Inflammopharmacology JO - Inflammopharmacology VL - 16 IS - 4 N2 - The in vitro antioxidant activity of the successive extracts (ethyl acetate, ethanol, methanol and water) of the leaves of Lagerstroemia speciosa L. (Lythraceae) were studied by examining their superoxide, hydroxyl ion scavenging and by measuring lipid peroxidation. The ethyl acetate and ethanol extracts were found to possess greater antioxidant property than the methanol and water extracts. Anti-inflammatory activity of the ethyl acetate and ethanol extracts were examined using the carrageenan-induced acute inflammation and formalin-induced (chronic) paw edema models. In acute and chronic inflammation models, the ethyl acetate extract reduced the paw edema significantly in a dose-dependent manner. Whereas, ethanol extract did not show dose-dependent activity. This results suggests that the anti-inflammatory activity is possibly attributed to its free radical scavenging activity. It was found that ethyl acetate extract reduced the inflammation more significantly than the ethanol extract. SN - 0925-4692 UR - https://www.unboundmedicine.com/medline/citation/18759076/Free_radical_scavenging_and_anti_inflammatory_properties_of_Lagerstroemia_speciosa__L__ L2 - https://dx.doi.org/10.1007/s10787-008-7002-6 DB - PRIME DP - Unbound Medicine ER -