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The Escherichia coli FtsK functional domains involved in its interaction with its divisome protein partners.
FEMS Microbiol Lett 2008; 287(2):163-7FM

Abstract

FtsK is a multifunctional protein involved in both cell division and chromosome segregation. As far as its role in cell division is concerned, FtsK is among the first divisome proteins that localizes at mid-cell, after FtsZ, FtsA and ZipA, and is required for the recruitment of the other divisome components. The ability of FtsK to interact with several cell division proteins, namely FtsZ, FtsQ, FtsL and FtsI, by the two-hybrid assay was already shown by our group. In this work, we describe the identification of the protein domain(s) involved in the interaction with the cell division partner proteins. The biological role of some interactions is also discussed.

Authors+Show Affiliations

Laboratorio di Microbiologia generale, Dipartimento di Biologia, Università Tor Vergata, Rome, Italy.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18759781

Citation

Grenga, Lucia, et al. "The Escherichia Coli FtsK Functional Domains Involved in Its Interaction With Its Divisome Protein Partners." FEMS Microbiology Letters, vol. 287, no. 2, 2008, pp. 163-7.
Grenga L, Luzi G, Paolozzi L, et al. The Escherichia coli FtsK functional domains involved in its interaction with its divisome protein partners. FEMS Microbiol Lett. 2008;287(2):163-7.
Grenga, L., Luzi, G., Paolozzi, L., & Ghelardini, P. (2008). The Escherichia coli FtsK functional domains involved in its interaction with its divisome protein partners. FEMS Microbiology Letters, 287(2), pp. 163-7. doi:10.1111/j.1574-6968.2008.01317.x.
Grenga L, et al. The Escherichia Coli FtsK Functional Domains Involved in Its Interaction With Its Divisome Protein Partners. FEMS Microbiol Lett. 2008;287(2):163-7. PubMed PMID: 18759781.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Escherichia coli FtsK functional domains involved in its interaction with its divisome protein partners. AU - Grenga,Lucia, AU - Luzi,Giuseppe, AU - Paolozzi,Luciano, AU - Ghelardini,Patrizia, Y1 - 2008/08/28/ PY - 2008/9/2/pubmed PY - 2008/11/14/medline PY - 2008/9/2/entrez SP - 163 EP - 7 JF - FEMS microbiology letters JO - FEMS Microbiol. Lett. VL - 287 IS - 2 N2 - FtsK is a multifunctional protein involved in both cell division and chromosome segregation. As far as its role in cell division is concerned, FtsK is among the first divisome proteins that localizes at mid-cell, after FtsZ, FtsA and ZipA, and is required for the recruitment of the other divisome components. The ability of FtsK to interact with several cell division proteins, namely FtsZ, FtsQ, FtsL and FtsI, by the two-hybrid assay was already shown by our group. In this work, we describe the identification of the protein domain(s) involved in the interaction with the cell division partner proteins. The biological role of some interactions is also discussed. SN - 0378-1097 UR - https://www.unboundmedicine.com/medline/citation/18759781/The_Escherichia_coli_FtsK_functional_domains_involved_in_its_interaction_with_its_divisome_protein_partners_ L2 - https://academic.oup.com/femsle/article-lookup/doi/10.1111/j.1574-6968.2008.01317.x DB - PRIME DP - Unbound Medicine ER -