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Improvement in the plasma omega-3 index by the use of a fish oil-enriched spread.
Ann Nutr Metab. 2008; 53(1):23-8.AN

Abstract

BACKGROUND

The main aim of this pilot study was to determine whether the omega-3 status can be improved by the use of a fish oil-enriched spread in a regular diet.

METHODS

The study started with an open arm where the participants consumed their regular diets followed by a randomized placebo-controlled arm with the inclusion of a spread which was either fish oil enriched or not (control). After each period,the fatty acid composition of red blood cell (RBC) and plasma phospholipids was determined by standard procedures and the sum of eicosapentaenoic and docosahexaenoic acid calculated. t tests were performed to calculate the significance. The first-order linear model was used to calculate correlations between selected parameters.

RESULTS

When the patients were on their usual diets, a strong correlation was found between the omega-3 index based on RBCs and plasma.In the group consuming the fish oil-enriched spread, the omega-3 index based on both RBCs and plasma was significantly higher after 3 weeks of intervention. This was not the case after intervention with the control spread.

CONCLUSION

Inclusion of reasonable amounts of a fish oil-enriched spread in an otherwise regular diet can be sufficient for obtaining a significant increase in omega-3 index.

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Authors+Show Affiliations

De Groote G
CRI Laboratories, Ghent-Zwijnaarde, Belgium.
De Laporte A
No affiliation info available
Dhondt G
No affiliation info available
Christophe A
No affiliation info available

MeSH

AdultDocosahexaenoic AcidsEicosapentaenoic AcidErythrocyte MembraneErythrocytesFatty Acids, Omega-3FemaleFish OilsFood, FortifiedHumansLinear ModelsMalePhospholipidsPilot Projects

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18772586

Citation

De Groote, Guy, et al. "Improvement in the Plasma Omega-3 Index By the Use of a Fish Oil-enriched Spread." Annals of Nutrition & Metabolism, vol. 53, no. 1, 2008, pp. 23-8.
De Groote G, De Laporte A, Dhondt G, et al. Improvement in the plasma omega-3 index by the use of a fish oil-enriched spread. Ann Nutr Metab. 2008;53(1):23-8.
De Groote, G., De Laporte, A., Dhondt, G., & Christophe, A. (2008). Improvement in the plasma omega-3 index by the use of a fish oil-enriched spread. Annals of Nutrition & Metabolism, 53(1), 23-8. https://doi.org/10.1159/000152870
De Groote G, et al. Improvement in the Plasma Omega-3 Index By the Use of a Fish Oil-enriched Spread. Ann Nutr Metab. 2008;53(1):23-8. PubMed PMID: 18772586.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Improvement in the plasma omega-3 index by the use of a fish oil-enriched spread. AU - De Groote,Guy, AU - De Laporte,André, AU - Dhondt,Goedele, AU - Christophe,Armand, Y1 - 2008/09/05/ PY - 2007/12/03/received PY - 2008/06/12/accepted PY - 2008/9/6/pubmed PY - 2009/1/28/medline PY - 2008/9/6/entrez SP - 23 EP - 8 JF - Annals of nutrition & metabolism JO - Ann Nutr Metab VL - 53 IS - 1 N2 - BACKGROUND: The main aim of this pilot study was to determine whether the omega-3 status can be improved by the use of a fish oil-enriched spread in a regular diet. METHODS: The study started with an open arm where the participants consumed their regular diets followed by a randomized placebo-controlled arm with the inclusion of a spread which was either fish oil enriched or not (control). After each period,the fatty acid composition of red blood cell (RBC) and plasma phospholipids was determined by standard procedures and the sum of eicosapentaenoic and docosahexaenoic acid calculated. t tests were performed to calculate the significance. The first-order linear model was used to calculate correlations between selected parameters. RESULTS: When the patients were on their usual diets, a strong correlation was found between the omega-3 index based on RBCs and plasma.In the group consuming the fish oil-enriched spread, the omega-3 index based on both RBCs and plasma was significantly higher after 3 weeks of intervention. This was not the case after intervention with the control spread. CONCLUSION: Inclusion of reasonable amounts of a fish oil-enriched spread in an otherwise regular diet can be sufficient for obtaining a significant increase in omega-3 index. SN - 1421-9697 UR - https://www.unboundmedicine.com/medline/citation/18772586/Improvement_in_the_plasma_omega_3_index_by_the_use_of_a_fish_oil_enriched_spread_ L2 - https://www.karger.com?DOI=10.1159/000152870 DB - PRIME DP - Unbound Medicine ER -