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[Injuries after lobectomy: a prospective randomized comparison of video-assisted thoracoscopic surgery and mini-thoracotomy].
Zhonghua Wai Ke Za Zhi. 2008 Mar 15; 46(6):401-4.ZW

Abstract

OBJECTIVE

To compare the differences of injuries and recovery between video-assisted thoracoscopic surgery (VATS) and mini-thoracotomy (MT) in patients with clinical early stage non-small cell lung cancer (NSCLC) after lobectomy.

METHODS

From March 2004 to December 2006, 47 consecutive patients with early stage NSCLC with a diameter of tumor less than 6 cm were recruited and randomized to VATS group and MT group. Incision length, duration of operation and intraoperative blood loss were recorded. Postoperative pain was assessed using a visual analogue scale before operation and daily for the first 7 days after operation. The serum levels of interleukin-6 (IL-6) and interleukin-10 (IL-10) were measured by cytometric bead array before operation and at 4, 24, and 48 h after operation. Karnofsky performance status (KPS) was assessed before operation and daily for the first 7 days after operation.

RESULTS

Incision length was (6.0 +/- 0. 9) cm in the VATS group and (12.5 +/- 1.5) cm in the MT group. There was no significant difference in duration of operation and intraoperative blood loss between the VATS group and the MT group. Postoperative pain was significantly less in the VATS group in the 5th to 7th day postoperatively (P < 0.05). There was no significant difference of serum concentrations of IL-6 and IL-10 between the VATS group and the MT group at 4, 24, and 48 h after operation. KPS score was significantly higher in the VATS group on 2nd to 7th day postoperatively (P < 0.05).

CONCLUSION

Compared with MT, VATS for lobectomy has less postoperative pain, faster recovery, but can't reduce postoperative release of cytokines.

Authors+Show Affiliations

State Key Laboratory of Oncology in South China, Lung Cancer Research Center, Sun Yat-sen University, Guangzhou 510060, China. drlongh@medmail.com.cnNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Randomized Controlled Trial

Language

chi

PubMed ID

18785569

Citation

Long, Hao, et al. "[Injuries After Lobectomy: a Prospective Randomized Comparison of Video-assisted Thoracoscopic Surgery and Mini-thoracotomy]." Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery], vol. 46, no. 6, 2008, pp. 401-4.
Long H, Lin ZC, Situ DR. [Injuries after lobectomy: a prospective randomized comparison of video-assisted thoracoscopic surgery and mini-thoracotomy]. Zhonghua Wai Ke Za Zhi. 2008;46(6):401-4.
Long, H., Lin, Z. C., & Situ, D. R. (2008). [Injuries after lobectomy: a prospective randomized comparison of video-assisted thoracoscopic surgery and mini-thoracotomy]. Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery], 46(6), 401-4.
Long H, Lin ZC, Situ DR. [Injuries After Lobectomy: a Prospective Randomized Comparison of Video-assisted Thoracoscopic Surgery and Mini-thoracotomy]. Zhonghua Wai Ke Za Zhi. 2008 Mar 15;46(6):401-4. PubMed PMID: 18785569.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Injuries after lobectomy: a prospective randomized comparison of video-assisted thoracoscopic surgery and mini-thoracotomy]. AU - Long,Hao, AU - Lin,Zhi-chao, AU - Situ,Dong-rong, PY - 2008/9/13/pubmed PY - 2009/4/22/medline PY - 2008/9/13/entrez SP - 401 EP - 4 JF - Zhonghua wai ke za zhi [Chinese journal of surgery] JO - Zhonghua Wai Ke Za Zhi VL - 46 IS - 6 N2 - OBJECTIVE: To compare the differences of injuries and recovery between video-assisted thoracoscopic surgery (VATS) and mini-thoracotomy (MT) in patients with clinical early stage non-small cell lung cancer (NSCLC) after lobectomy. METHODS: From March 2004 to December 2006, 47 consecutive patients with early stage NSCLC with a diameter of tumor less than 6 cm were recruited and randomized to VATS group and MT group. Incision length, duration of operation and intraoperative blood loss were recorded. Postoperative pain was assessed using a visual analogue scale before operation and daily for the first 7 days after operation. The serum levels of interleukin-6 (IL-6) and interleukin-10 (IL-10) were measured by cytometric bead array before operation and at 4, 24, and 48 h after operation. Karnofsky performance status (KPS) was assessed before operation and daily for the first 7 days after operation. RESULTS: Incision length was (6.0 +/- 0. 9) cm in the VATS group and (12.5 +/- 1.5) cm in the MT group. There was no significant difference in duration of operation and intraoperative blood loss between the VATS group and the MT group. Postoperative pain was significantly less in the VATS group in the 5th to 7th day postoperatively (P < 0.05). There was no significant difference of serum concentrations of IL-6 and IL-10 between the VATS group and the MT group at 4, 24, and 48 h after operation. KPS score was significantly higher in the VATS group on 2nd to 7th day postoperatively (P < 0.05). CONCLUSION: Compared with MT, VATS for lobectomy has less postoperative pain, faster recovery, but can't reduce postoperative release of cytokines. SN - 0529-5815 UR - https://www.unboundmedicine.com/medline/citation/18785569/[Injuries_after_lobectomy:_a_prospective_randomized_comparison_of_video_assisted_thoracoscopic_surgery_and_mini_thoracotomy]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0529-5815&amp;year=2008&amp;vol=46&amp;issue=6&amp;fpage=401 DB - PRIME DP - Unbound Medicine ER -