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Predictors of outcome three years after diagnosis of first episode psychosis.
Psychiatry Res. 2008 Oct 30; 161(1):11-8.PR

Abstract

This study aimed to determine which of demographic/premorbid, psychiatric or neuropsychological factors best predict functional outcome at 3 years after a first episode of psychotic illness. This will, it is hoped, identify prognostic indicators of longer term outcomes, as well as targets for rehabilitation. The Western Sydney First Episode Psychosis Project collected data on young people (aged 13 to 25) presenting with newly diagnosed psychosis at baseline and 3-year follow-up (n=52). Outcome was measured using the Role Functioning Scale (RFS) and the Clinical Global Impression Scale--severity of illness measure (CGI-S). Multiple regression analyses were performed to identify baseline predictors of outcome. The Premorbid Social Adjustment Scale in Adolescence (PSAS-Adolescent) and the Verbal Comprehension Index from the WAIS-III were found to be the two significant predictors for RFS, with only the former (PSAS-Adolescent) predicting CGI-S. Demographic and neuropsychological measures relating to premorbid functioning were the best predictors of long-term outcome in first episode psychosis, with baseline psychiatric symptoms not contributing.

Authors+Show Affiliations

Department of Medical Psychology, Westmead Hospital, Westmead NSW, Australia. saraklucas@optusnet.com.auNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18786728

Citation

Lucas, Sara, et al. "Predictors of Outcome Three Years After Diagnosis of First Episode Psychosis." Psychiatry Research, vol. 161, no. 1, 2008, pp. 11-8.
Lucas S, Redoblado-Hodge MA, Shores A, et al. Predictors of outcome three years after diagnosis of first episode psychosis. Psychiatry Res. 2008;161(1):11-8.
Lucas, S., Redoblado-Hodge, M. A., Shores, A., Brennan, J., & Harris, A. (2008). Predictors of outcome three years after diagnosis of first episode psychosis. Psychiatry Research, 161(1), 11-8. https://doi.org/10.1016/j.psychres.2007.10.004
Lucas S, et al. Predictors of Outcome Three Years After Diagnosis of First Episode Psychosis. Psychiatry Res. 2008 Oct 30;161(1):11-8. PubMed PMID: 18786728.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Predictors of outcome three years after diagnosis of first episode psychosis. AU - Lucas,Sara, AU - Redoblado-Hodge,Marie Antoinette, AU - Shores,Arthur, AU - Brennan,John, AU - Harris,Anthony, Y1 - 2008/09/10/ PY - 2007/01/09/received PY - 2007/08/24/revised PY - 2007/10/09/accepted PY - 2008/9/13/pubmed PY - 2009/2/3/medline PY - 2008/9/13/entrez SP - 11 EP - 8 JF - Psychiatry research JO - Psychiatry Res VL - 161 IS - 1 N2 - This study aimed to determine which of demographic/premorbid, psychiatric or neuropsychological factors best predict functional outcome at 3 years after a first episode of psychotic illness. This will, it is hoped, identify prognostic indicators of longer term outcomes, as well as targets for rehabilitation. The Western Sydney First Episode Psychosis Project collected data on young people (aged 13 to 25) presenting with newly diagnosed psychosis at baseline and 3-year follow-up (n=52). Outcome was measured using the Role Functioning Scale (RFS) and the Clinical Global Impression Scale--severity of illness measure (CGI-S). Multiple regression analyses were performed to identify baseline predictors of outcome. The Premorbid Social Adjustment Scale in Adolescence (PSAS-Adolescent) and the Verbal Comprehension Index from the WAIS-III were found to be the two significant predictors for RFS, with only the former (PSAS-Adolescent) predicting CGI-S. Demographic and neuropsychological measures relating to premorbid functioning were the best predictors of long-term outcome in first episode psychosis, with baseline psychiatric symptoms not contributing. SN - 0165-1781 UR - https://www.unboundmedicine.com/medline/citation/18786728/Predictors_of_outcome_three_years_after_diagnosis_of_first_episode_psychosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-1781(07)00353-8 DB - PRIME DP - Unbound Medicine ER -