Tags

Type your tag names separated by a space and hit enter

Moderate alcohol drinking might be protective for systemic lupus erythematosus: a systematic review and meta-analysis.

Abstract

Conflicting evidence for the effect of moderate alcohol drinking on the development of systemic lupus erythematosus (SLE) existed at present. In the current study, we performed an extensive search of relevant studies and performed a meta-analysis to obtain a more precise estimate. Thirty-eight studies were identified from electronic databases and chosen for detailed review, then six articles from six case-control studies with one cohort study were included in our meta-analyses. Meta-analyses were divided into two subgroups in which patients in the study of Washio et al. treated for less than 5 years (subgroup A) or less than 10 years (subgroup B) were involved, respectively. The odds ratio (OR) of moderate alcohol drinking in the meta-analyses of subgroup B for the development of SLE was significantly decreased (OR 0.723, 95% confidence interval (95% CI) 0.547-0.954), while moderate alcohol drinking in the meta-analysis of subgroup A did not demonstrate a decreased risk of SLE (OR 0.780, 95% CI 0.491-1.240). Meta-analyses of six case-control studies in the two subgroups both demonstrated that moderate alcohol drinking had a protective effect on the development of SLE. Taken together, our results show that moderate alcohol drinking might be protective for SLE.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui 230032, People's Republic of China.

    , , ,

    Source

    Clinical rheumatology 27:12 2008 Dec pg 1557-63

    MeSH

    Alcohol Drinking
    Case-Control Studies
    Female
    Humans
    Longitudinal Studies
    Lupus Erythematosus, Systemic
    Male
    Odds Ratio

    Pub Type(s)

    Journal Article
    Meta-Analysis
    Research Support, Non-U.S. Gov't
    Review
    Systematic Review

    Language

    eng

    PubMed ID

    18795396

    Citation

    Wang, Jing, et al. "Moderate Alcohol Drinking Might Be Protective for Systemic Lupus Erythematosus: a Systematic Review and Meta-analysis." Clinical Rheumatology, vol. 27, no. 12, 2008, pp. 1557-63.
    Wang J, Pan HF, Ye DQ, et al. Moderate alcohol drinking might be protective for systemic lupus erythematosus: a systematic review and meta-analysis. Clin Rheumatol. 2008;27(12):1557-63.
    Wang, J., Pan, H. F., Ye, D. Q., Su, H., & Li, X. P. (2008). Moderate alcohol drinking might be protective for systemic lupus erythematosus: a systematic review and meta-analysis. Clinical Rheumatology, 27(12), pp. 1557-63. doi:10.1007/s10067-008-1004-z.
    Wang J, et al. Moderate Alcohol Drinking Might Be Protective for Systemic Lupus Erythematosus: a Systematic Review and Meta-analysis. Clin Rheumatol. 2008;27(12):1557-63. PubMed PMID: 18795396.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Moderate alcohol drinking might be protective for systemic lupus erythematosus: a systematic review and meta-analysis. AU - Wang,Jing, AU - Pan,Hai-Feng, AU - Ye,Dong-Qing, AU - Su,Hong, AU - Li,Xiang-Pei, Y1 - 2008/09/16/ PY - 2008/06/25/received PY - 2008/08/27/accepted PY - 2008/08/26/revised PY - 2008/9/17/pubmed PY - 2009/4/14/medline PY - 2008/9/17/entrez SP - 1557 EP - 63 JF - Clinical rheumatology JO - Clin. Rheumatol. VL - 27 IS - 12 N2 - Conflicting evidence for the effect of moderate alcohol drinking on the development of systemic lupus erythematosus (SLE) existed at present. In the current study, we performed an extensive search of relevant studies and performed a meta-analysis to obtain a more precise estimate. Thirty-eight studies were identified from electronic databases and chosen for detailed review, then six articles from six case-control studies with one cohort study were included in our meta-analyses. Meta-analyses were divided into two subgroups in which patients in the study of Washio et al. treated for less than 5 years (subgroup A) or less than 10 years (subgroup B) were involved, respectively. The odds ratio (OR) of moderate alcohol drinking in the meta-analyses of subgroup B for the development of SLE was significantly decreased (OR 0.723, 95% confidence interval (95% CI) 0.547-0.954), while moderate alcohol drinking in the meta-analysis of subgroup A did not demonstrate a decreased risk of SLE (OR 0.780, 95% CI 0.491-1.240). Meta-analyses of six case-control studies in the two subgroups both demonstrated that moderate alcohol drinking had a protective effect on the development of SLE. Taken together, our results show that moderate alcohol drinking might be protective for SLE. SN - 1434-9949 UR - https://www.unboundmedicine.com/medline/citation/18795396/full_citation L2 - https://dx.doi.org/10.1007/s10067-008-1004-z DB - PRIME DP - Unbound Medicine ER -