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Tsukamurella: a cause of catheter-related bloodstream infections.
Eur J Clin Microbiol Infect Dis. 2009 Feb; 28(2):203-10.EJ

Abstract

Tsukamurellae are strictly aerobic Gram-positive rods that can be easily misidentified as Corynebacterium species, Rhodococcus species, Nocardia species, Mycobacterium species, or other Gram-positive aerobic rods. They have been uncommonly reported as a cause of different human infections, including bloodstream infections. We describe 2 new cases of catheter-related bloodstream infections (CR-BSI) caused by Tsukamurella species and review 12 similar cases reported in the literature. Conventional procedures have often misidentified Tsukamurella species as other aerobic Gram-positive rods. This misidentification could be avoided using genotyping. All cases ultimately required the withdrawal of the infected line. The literature provides no firm conclusions regarding ideal choice or duration of antimicrobial therapy for this infection. Tsukamurella species should be added to the list of agents able to produce CR-BSI. Genotypic methods such as PCR 16S rRNA can allow a reliable identification at the genus level of Tsukamurella strains faster than a combination of conventional phenotypic methods.

Authors+Show Affiliations

Department of Clinical Microbiology and Infectious Diseases Service, Hospital General Universitario Gregorio Marañón, Doctor Esquerdo 46, 28007, Madrid, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18810513

Citation

Bouza, E, et al. "Tsukamurella: a Cause of Catheter-related Bloodstream Infections." European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, vol. 28, no. 2, 2009, pp. 203-10.
Bouza E, Pérez-Parra A, Rosal M, et al. Tsukamurella: a cause of catheter-related bloodstream infections. Eur J Clin Microbiol Infect Dis. 2009;28(2):203-10.
Bouza, E., Pérez-Parra, A., Rosal, M., Martín-Rabadán, P., Rodríguez-Créixems, M., & Marín, M. (2009). Tsukamurella: a cause of catheter-related bloodstream infections. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, 28(2), 203-10. https://doi.org/10.1007/s10096-008-0607-2
Bouza E, et al. Tsukamurella: a Cause of Catheter-related Bloodstream Infections. Eur J Clin Microbiol Infect Dis. 2009;28(2):203-10. PubMed PMID: 18810513.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Tsukamurella: a cause of catheter-related bloodstream infections. AU - Bouza,E, AU - Pérez-Parra,A, AU - Rosal,M, AU - Martín-Rabadán,P, AU - Rodríguez-Créixems,M, AU - Marín,M, Y1 - 2008/09/23/ PY - 2008/02/05/received PY - 2008/07/25/accepted PY - 2008/9/24/pubmed PY - 2009/8/8/medline PY - 2008/9/24/entrez SP - 203 EP - 10 JF - European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology JO - Eur. J. Clin. Microbiol. Infect. Dis. VL - 28 IS - 2 N2 - Tsukamurellae are strictly aerobic Gram-positive rods that can be easily misidentified as Corynebacterium species, Rhodococcus species, Nocardia species, Mycobacterium species, or other Gram-positive aerobic rods. They have been uncommonly reported as a cause of different human infections, including bloodstream infections. We describe 2 new cases of catheter-related bloodstream infections (CR-BSI) caused by Tsukamurella species and review 12 similar cases reported in the literature. Conventional procedures have often misidentified Tsukamurella species as other aerobic Gram-positive rods. This misidentification could be avoided using genotyping. All cases ultimately required the withdrawal of the infected line. The literature provides no firm conclusions regarding ideal choice or duration of antimicrobial therapy for this infection. Tsukamurella species should be added to the list of agents able to produce CR-BSI. Genotypic methods such as PCR 16S rRNA can allow a reliable identification at the genus level of Tsukamurella strains faster than a combination of conventional phenotypic methods. SN - 1435-4373 UR - https://www.unboundmedicine.com/medline/citation/18810513/Tsukamurella:_a_cause_of_catheter_related_bloodstream_infections_ L2 - https://dx.doi.org/10.1007/s10096-008-0607-2 DB - PRIME DP - Unbound Medicine ER -