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A study of clinico-haematological profiles of pancytopenia in children.
Trop Doct. 2008 Oct; 38(4):241-3.TD

Abstract

We report on the clinico-haematological profile of pancytopenia in children from the Departments of Pediatrics and Pathology, Institute of Medical Sciences, Banaras Hindu University, India, over a period of 30 months. Pancytopenia was defined as: haemoglobin <10 g/dL, absolute neutrophil count 1.5 x 10(9)/L and platelet count <100 x 10(9)/L. A detailed history, clinical examination and haematological parameters were recorded. Bone marrow aspiration and trephine biopsy were carried out in all cases. One hundred and five cases aged 1.5-18 years, with a mean age of 8.6 years, were included in the study. Aplastic anaemia was the most common cause of pancytopenia (43%) followed by acute leukaemia (25%). Infections were the third most common cause of pancytopenia of which kala azar was the most common. Megaloblastic anaemia was seen in 6.7%.

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Authors+Show Affiliations

Gupta V
Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India. vineetaguptabhu@gmail.com
Tripathi S
No affiliation info available
Tilak V
No affiliation info available
Bhatia BD
No affiliation info available

MeSH

AdolescentAnemia, AplasticChildChild, PreschoolFemaleHumansInfantLeishmaniasis, VisceralLeukemiaMalePancytopenia

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18820199

Citation

Gupta, V, et al. "A Study of Clinico-haematological Profiles of Pancytopenia in Children." Tropical Doctor, vol. 38, no. 4, 2008, pp. 241-3.
Gupta V, Tripathi S, Tilak V, et al. A study of clinico-haematological profiles of pancytopenia in children. Trop Doct. 2008;38(4):241-3.
Gupta, V., Tripathi, S., Tilak, V., & Bhatia, B. D. (2008). A study of clinico-haematological profiles of pancytopenia in children. Tropical Doctor, 38(4), 241-3. https://doi.org/10.1258/td.2008.070422
Gupta V, et al. A Study of Clinico-haematological Profiles of Pancytopenia in Children. Trop Doct. 2008;38(4):241-3. PubMed PMID: 18820199.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A study of clinico-haematological profiles of pancytopenia in children. AU - Gupta,V, AU - Tripathi,S, AU - Tilak,V, AU - Bhatia,B D, PY - 2008/9/30/pubmed PY - 2008/12/17/medline PY - 2008/9/30/entrez SP - 241 EP - 3 JF - Tropical doctor JO - Trop Doct VL - 38 IS - 4 N2 - We report on the clinico-haematological profile of pancytopenia in children from the Departments of Pediatrics and Pathology, Institute of Medical Sciences, Banaras Hindu University, India, over a period of 30 months. Pancytopenia was defined as: haemoglobin <10 g/dL, absolute neutrophil count 1.5 x 10(9)/L and platelet count <100 x 10(9)/L. A detailed history, clinical examination and haematological parameters were recorded. Bone marrow aspiration and trephine biopsy were carried out in all cases. One hundred and five cases aged 1.5-18 years, with a mean age of 8.6 years, were included in the study. Aplastic anaemia was the most common cause of pancytopenia (43%) followed by acute leukaemia (25%). Infections were the third most common cause of pancytopenia of which kala azar was the most common. Megaloblastic anaemia was seen in 6.7%. SN - 0049-4755 UR - https://www.unboundmedicine.com/medline/citation/18820199/A_study_of_clinico_haematological_profiles_of_pancytopenia_in_children_ L2 - https://journals.sagepub.com/doi/10.1258/td.2008.070422?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -