Tags

Type your tag names separated by a space and hit enter

Endemic and epidemic lineages of Escherichia coli that cause urinary tract infections.
Emerg Infect Dis. 2008 Oct; 14(10):1575-83.EI

Abstract

Women with urinary tract infections (UTIs) in California, USA (1999-2001), were infected with closely related or indistinguishable strains of Escherichia coli (clonal groups), which suggests point source dissemination. We compared strains of UTI-causing E. coli in California with strains causing such infections in Montréal, Québec, Canada. Urine specimens from women with community-acquired UTIs in Montréal (2006) were cultured for E. coli. Isolates that caused 256 consecutive episodes of UTI were characterized by antimicrobial drug susceptibility profile, enterobacterial repetitive intergenic consensus 2 PCR, serotyping, XbaI and NotI pulsed-field gel electrophoresis, multilocus sequence typing, and phylogenetic typing. We confirmed the presence of drug-resistant, genetically related, and temporally clustered E. coli clonal groups that caused community-acquired UTIs in unrelated women in 2 locations and 2 different times. Two clonal groups were identified in both locations. Epidemic transmission followed by endemic transmission of UTI-causing clonal groups may explain these clusters of UTI cases.

Authors+Show Affiliations

Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada. amee.manges@mcgill.caNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18826822

Citation

Manges, Amee R., et al. "Endemic and Epidemic Lineages of Escherichia Coli That Cause Urinary Tract Infections." Emerging Infectious Diseases, vol. 14, no. 10, 2008, pp. 1575-83.
Manges AR, Tabor H, Tellis P, et al. Endemic and epidemic lineages of Escherichia coli that cause urinary tract infections. Emerg Infect Dis. 2008;14(10):1575-83.
Manges, A. R., Tabor, H., Tellis, P., Vincent, C., & Tellier, P. P. (2008). Endemic and epidemic lineages of Escherichia coli that cause urinary tract infections. Emerging Infectious Diseases, 14(10), 1575-83. https://doi.org/10.3201/eid1410.080102
Manges AR, et al. Endemic and Epidemic Lineages of Escherichia Coli That Cause Urinary Tract Infections. Emerg Infect Dis. 2008;14(10):1575-83. PubMed PMID: 18826822.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endemic and epidemic lineages of Escherichia coli that cause urinary tract infections. AU - Manges,Amee R, AU - Tabor,Helen, AU - Tellis,Patricia, AU - Vincent,Caroline, AU - Tellier,Pierre-Paul, PY - 2008/10/2/pubmed PY - 2008/11/15/medline PY - 2008/10/2/entrez SP - 1575 EP - 83 JF - Emerging infectious diseases JO - Emerg Infect Dis VL - 14 IS - 10 N2 - Women with urinary tract infections (UTIs) in California, USA (1999-2001), were infected with closely related or indistinguishable strains of Escherichia coli (clonal groups), which suggests point source dissemination. We compared strains of UTI-causing E. coli in California with strains causing such infections in Montréal, Québec, Canada. Urine specimens from women with community-acquired UTIs in Montréal (2006) were cultured for E. coli. Isolates that caused 256 consecutive episodes of UTI were characterized by antimicrobial drug susceptibility profile, enterobacterial repetitive intergenic consensus 2 PCR, serotyping, XbaI and NotI pulsed-field gel electrophoresis, multilocus sequence typing, and phylogenetic typing. We confirmed the presence of drug-resistant, genetically related, and temporally clustered E. coli clonal groups that caused community-acquired UTIs in unrelated women in 2 locations and 2 different times. Two clonal groups were identified in both locations. Epidemic transmission followed by endemic transmission of UTI-causing clonal groups may explain these clusters of UTI cases. SN - 1080-6059 UR - https://www.unboundmedicine.com/medline/citation/18826822/Endemic_and_epidemic_lineages_of_Escherichia_coli_that_cause_urinary_tract_infections_ L2 - https://dx.doi.org/10.3201/eid1410.080102 DB - PRIME DP - Unbound Medicine ER -