Tags

Type your tag names separated by a space and hit enter

Silica-void-gold nanoparticles: temporally stable surface-enhanced Raman scattering substrates.
J Am Chem Soc. 2008 Oct 29; 130(43):14273-9.JA

Abstract

Reproducible detection of a target molecule is demonstrated using temporally stable solution-phase silica-void-gold nanoparticles and surface-enhanced Raman scattering (SERS). These composite nanostructures are homogeneous (diameter = 45 +/- 4 nm) and entrap single 13 nm gold nanoparticle cores inside porous silica membranes which prevent electromagnetic coupling and aggregation between adjacent nanoparticles. The optical properties of the gold nanoparticle cores and structural changes of the composite nanostructures are characterized using extinction spectroscopy and transmission electron microscopy, respectively, and both techniques are used to monitor the formation of the silica membrane. The resulting nanostructures exhibit temporally stable optical properties in the presence of salt and 2-naphthalenethiol. Similar SERS spectral features are observed when 2-naphthalenethiol is incubated with both bare and membrane-encapsulated gold nanoparticles. Disappearance of the S-H Raman vibrational band centered at 2566 cm(-1) with the composite nanoparticles indicates that the target molecule is binding directly to the metal surface. Furthermore, these nanostructures exhibit reproducible SERS signals for at least a 2 h period. This first demonstration of utilizing solution-phase silica-void-gold nanoparticles as reproducible SERS substrates will allow for future fundamental studies in understanding the mechanisms of SERS using solution-phase nanostructures as well as for applications that involve the direct and reproducible detection of biological and environmental molecules.

Authors+Show Affiliations

Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18831552

Citation

Roca, Maryuri, and Amanda J. Haes. "Silica-void-gold Nanoparticles: Temporally Stable Surface-enhanced Raman Scattering Substrates." Journal of the American Chemical Society, vol. 130, no. 43, 2008, pp. 14273-9.
Roca M, Haes AJ. Silica-void-gold nanoparticles: temporally stable surface-enhanced Raman scattering substrates. J Am Chem Soc. 2008;130(43):14273-9.
Roca, M., & Haes, A. J. (2008). Silica-void-gold nanoparticles: temporally stable surface-enhanced Raman scattering substrates. Journal of the American Chemical Society, 130(43), 14273-9. https://doi.org/10.1021/ja8059039
Roca M, Haes AJ. Silica-void-gold Nanoparticles: Temporally Stable Surface-enhanced Raman Scattering Substrates. J Am Chem Soc. 2008 Oct 29;130(43):14273-9. PubMed PMID: 18831552.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Silica-void-gold nanoparticles: temporally stable surface-enhanced Raman scattering substrates. AU - Roca,Maryuri, AU - Haes,Amanda J, Y1 - 2008/10/03/ PY - 2008/10/4/pubmed PY - 2009/1/29/medline PY - 2008/10/4/entrez SP - 14273 EP - 9 JF - Journal of the American Chemical Society JO - J Am Chem Soc VL - 130 IS - 43 N2 - Reproducible detection of a target molecule is demonstrated using temporally stable solution-phase silica-void-gold nanoparticles and surface-enhanced Raman scattering (SERS). These composite nanostructures are homogeneous (diameter = 45 +/- 4 nm) and entrap single 13 nm gold nanoparticle cores inside porous silica membranes which prevent electromagnetic coupling and aggregation between adjacent nanoparticles. The optical properties of the gold nanoparticle cores and structural changes of the composite nanostructures are characterized using extinction spectroscopy and transmission electron microscopy, respectively, and both techniques are used to monitor the formation of the silica membrane. The resulting nanostructures exhibit temporally stable optical properties in the presence of salt and 2-naphthalenethiol. Similar SERS spectral features are observed when 2-naphthalenethiol is incubated with both bare and membrane-encapsulated gold nanoparticles. Disappearance of the S-H Raman vibrational band centered at 2566 cm(-1) with the composite nanoparticles indicates that the target molecule is binding directly to the metal surface. Furthermore, these nanostructures exhibit reproducible SERS signals for at least a 2 h period. This first demonstration of utilizing solution-phase silica-void-gold nanoparticles as reproducible SERS substrates will allow for future fundamental studies in understanding the mechanisms of SERS using solution-phase nanostructures as well as for applications that involve the direct and reproducible detection of biological and environmental molecules. SN - 1520-5126 UR - https://www.unboundmedicine.com/medline/citation/18831552/Silica_void_gold_nanoparticles:_temporally_stable_surface_enhanced_Raman_scattering_substrates_ L2 - https://doi.org/10.1021/ja8059039 DB - PRIME DP - Unbound Medicine ER -