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Increased stroke risk is related to a binge-drinking habit.

Abstract

BACKGROUND AND PURPOSE

Heavy alcohol consumption increases the risk for all strokes, whereas moderate regular alcohol consumption is associated with a lower risk for ischemic stroke. The purpose of this study was to evaluate the effect of different drinking patterns on stroke risk, independent of average alcohol intake.

METHODS

A prospective cohort study of 15 965 Finnish men and women age 25 to 64 years who participated in a national risk factor survey and had no history of stroke at baseline were followed up for a 10-year period. The first stroke event during follow-up served as the outcome of interest (N=249 strokes). A binge drinking pattern was defined as consuming 6 or more drinks of the same alcoholic beverage in men or 4 or more drinks in women in 1 session. Cox proportional-hazards models were adjusted for average alcohol consumption, age, sex, hypertension, smoking, diabetes, body mass index, educational status, study area, study year, and history of myocardial infarction.

RESULTS

Binge drinking was an independent risk factor for total and ischemic strokes. Compared with non-binge drinkers, the hazard ratio for total strokes among binge drinkers was 1.85 (95% CI, 1.35 to 2.54) after adjusting for average alcohol consumption, age, and sex; the association was diluted after adjustment for other risk factors. Compared with non-binge drinkers, the risk for ischemic stroke was 1.99 (95% CI, 1.39 to 2.87) among binge drinkers; the association remained statistically significant after adjustment for potential confounders.

CONCLUSIONS

This study found that a pattern of binge drinking is an independent risk factor for all strokes and ischemic stroke.

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  • Authors+Show Affiliations

    ,

    National Public Health Institute, Helsinki, Finland.

    , , ,

    Source

    Stroke 39:12 2008 Dec pg 3179-84

    MeSH

    Adult
    Alcohol Drinking
    Anthropometry
    Cause of Death
    Cerebral Hemorrhage
    Cohort Studies
    Educational Status
    Female
    Finland
    Habits
    Humans
    Male
    Middle Aged
    Prospective Studies
    Sampling Studies
    Smoking
    Stroke

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    18832741

    Citation

    Sundell, Laura, et al. "Increased Stroke Risk Is Related to a Binge-drinking Habit." Stroke, vol. 39, no. 12, 2008, pp. 3179-84.
    Sundell L, Salomaa V, Vartiainen E, et al. Increased stroke risk is related to a binge-drinking habit. Stroke. 2008;39(12):3179-84.
    Sundell, L., Salomaa, V., Vartiainen, E., Poikolainen, K., & Laatikainen, T. (2008). Increased stroke risk is related to a binge-drinking habit. Stroke, 39(12), pp. 3179-84. doi:10.1161/STROKEAHA.108.520817.
    Sundell L, et al. Increased Stroke Risk Is Related to a Binge-drinking Habit. Stroke. 2008;39(12):3179-84. PubMed PMID: 18832741.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Increased stroke risk is related to a binge-drinking habit. AU - Sundell,Laura, AU - Salomaa,Veikko, AU - Vartiainen,Erkki, AU - Poikolainen,Kari, AU - Laatikainen,Tiina, Y1 - 2008/10/02/ PY - 2008/10/4/pubmed PY - 2009/1/7/medline PY - 2008/10/4/entrez SP - 3179 EP - 84 JF - Stroke JO - Stroke VL - 39 IS - 12 N2 - BACKGROUND AND PURPOSE: Heavy alcohol consumption increases the risk for all strokes, whereas moderate regular alcohol consumption is associated with a lower risk for ischemic stroke. The purpose of this study was to evaluate the effect of different drinking patterns on stroke risk, independent of average alcohol intake. METHODS: A prospective cohort study of 15 965 Finnish men and women age 25 to 64 years who participated in a national risk factor survey and had no history of stroke at baseline were followed up for a 10-year period. The first stroke event during follow-up served as the outcome of interest (N=249 strokes). A binge drinking pattern was defined as consuming 6 or more drinks of the same alcoholic beverage in men or 4 or more drinks in women in 1 session. Cox proportional-hazards models were adjusted for average alcohol consumption, age, sex, hypertension, smoking, diabetes, body mass index, educational status, study area, study year, and history of myocardial infarction. RESULTS: Binge drinking was an independent risk factor for total and ischemic strokes. Compared with non-binge drinkers, the hazard ratio for total strokes among binge drinkers was 1.85 (95% CI, 1.35 to 2.54) after adjusting for average alcohol consumption, age, and sex; the association was diluted after adjustment for other risk factors. Compared with non-binge drinkers, the risk for ischemic stroke was 1.99 (95% CI, 1.39 to 2.87) among binge drinkers; the association remained statistically significant after adjustment for potential confounders. CONCLUSIONS: This study found that a pattern of binge drinking is an independent risk factor for all strokes and ischemic stroke. SN - 1524-4628 UR - https://www.unboundmedicine.com/medline/citation/18832741/Increased_stroke_risk_is_related_to_a_binge_drinking_habit_ L2 - http://www.ahajournals.org/doi/full/10.1161/STROKEAHA.108.520817?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -