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Increased stroke risk is related to a binge-drinking habit.
Stroke 2008; 39(12):3179-84S

Abstract

BACKGROUND AND PURPOSE

Heavy alcohol consumption increases the risk for all strokes, whereas moderate regular alcohol consumption is associated with a lower risk for ischemic stroke. The purpose of this study was to evaluate the effect of different drinking patterns on stroke risk, independent of average alcohol intake.

METHODS

A prospective cohort study of 15 965 Finnish men and women age 25 to 64 years who participated in a national risk factor survey and had no history of stroke at baseline were followed up for a 10-year period. The first stroke event during follow-up served as the outcome of interest (N=249 strokes). A binge drinking pattern was defined as consuming 6 or more drinks of the same alcoholic beverage in men or 4 or more drinks in women in 1 session. Cox proportional-hazards models were adjusted for average alcohol consumption, age, sex, hypertension, smoking, diabetes, body mass index, educational status, study area, study year, and history of myocardial infarction.

RESULTS

Binge drinking was an independent risk factor for total and ischemic strokes. Compared with non-binge drinkers, the hazard ratio for total strokes among binge drinkers was 1.85 (95% CI, 1.35 to 2.54) after adjusting for average alcohol consumption, age, and sex; the association was diluted after adjustment for other risk factors. Compared with non-binge drinkers, the risk for ischemic stroke was 1.99 (95% CI, 1.39 to 2.87) among binge drinkers; the association remained statistically significant after adjustment for potential confounders.

CONCLUSIONS

This study found that a pattern of binge drinking is an independent risk factor for all strokes and ischemic stroke.

Authors+Show Affiliations

National Public Health Institute, Helsinki, Finland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18832741

Citation

Sundell, Laura, et al. "Increased Stroke Risk Is Related to a Binge-drinking Habit." Stroke, vol. 39, no. 12, 2008, pp. 3179-84.
Sundell L, Salomaa V, Vartiainen E, et al. Increased stroke risk is related to a binge-drinking habit. Stroke. 2008;39(12):3179-84.
Sundell, L., Salomaa, V., Vartiainen, E., Poikolainen, K., & Laatikainen, T. (2008). Increased stroke risk is related to a binge-drinking habit. Stroke, 39(12), pp. 3179-84. doi:10.1161/STROKEAHA.108.520817.
Sundell L, et al. Increased Stroke Risk Is Related to a Binge-drinking Habit. Stroke. 2008;39(12):3179-84. PubMed PMID: 18832741.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Increased stroke risk is related to a binge-drinking habit. AU - Sundell,Laura, AU - Salomaa,Veikko, AU - Vartiainen,Erkki, AU - Poikolainen,Kari, AU - Laatikainen,Tiina, Y1 - 2008/10/02/ PY - 2008/10/4/pubmed PY - 2009/1/7/medline PY - 2008/10/4/entrez SP - 3179 EP - 84 JF - Stroke JO - Stroke VL - 39 IS - 12 N2 - BACKGROUND AND PURPOSE: Heavy alcohol consumption increases the risk for all strokes, whereas moderate regular alcohol consumption is associated with a lower risk for ischemic stroke. The purpose of this study was to evaluate the effect of different drinking patterns on stroke risk, independent of average alcohol intake. METHODS: A prospective cohort study of 15 965 Finnish men and women age 25 to 64 years who participated in a national risk factor survey and had no history of stroke at baseline were followed up for a 10-year period. The first stroke event during follow-up served as the outcome of interest (N=249 strokes). A binge drinking pattern was defined as consuming 6 or more drinks of the same alcoholic beverage in men or 4 or more drinks in women in 1 session. Cox proportional-hazards models were adjusted for average alcohol consumption, age, sex, hypertension, smoking, diabetes, body mass index, educational status, study area, study year, and history of myocardial infarction. RESULTS: Binge drinking was an independent risk factor for total and ischemic strokes. Compared with non-binge drinkers, the hazard ratio for total strokes among binge drinkers was 1.85 (95% CI, 1.35 to 2.54) after adjusting for average alcohol consumption, age, and sex; the association was diluted after adjustment for other risk factors. Compared with non-binge drinkers, the risk for ischemic stroke was 1.99 (95% CI, 1.39 to 2.87) among binge drinkers; the association remained statistically significant after adjustment for potential confounders. CONCLUSIONS: This study found that a pattern of binge drinking is an independent risk factor for all strokes and ischemic stroke. SN - 1524-4628 UR - https://www.unboundmedicine.com/medline/citation/18832741/Increased_stroke_risk_is_related_to_a_binge_drinking_habit_ L2 - http://www.ahajournals.org/doi/full/10.1161/STROKEAHA.108.520817?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -