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Le Fort I osteotomy for extensive juvenile nasopharyngeal angiofibroma: a retrospective study.
Adv Ther. 2008 Oct; 25(10):1057-64.AT

Abstract

INTRODUCTION

Juvenile nasopharyngeal angiofibroma (JNA) is a rare, nonencapsulated, benign neoplasm typically diagnosed in adolescent boys. Surgery is the usual treatment modality for JNA. The optimal surgical procedure should allow maximal exposure of the tumor for complete excision with minimum morbidity. One possible surgical approach is Le Fort I maxillary osteotomy. The aim of this study was to review our experience with the Le Fort I osteotomy and to investigate the feasibility of this approach for extensive JNA invaded into pterygopalatine and infratemporal fossae.

METHODS

We retrospectively studied patients who had undergone JNA resection via the Le Fort I osteotomy approach from July 2000 to September 2007, considering tumor location and size, complications, and tumor recurrence associated with the surgical approach.

RESULTS

Six patients of JNA (all boys; mean age, 15.5 years) were identified through the chart review. All the angiofibromas had extended into the pterygomaxillary space and infratemporal fossa. The mean follow-up for this cohort was 50.1 months. No intraoperative and postoperative complications were noted, except for slight diplopia in one patient due to injury of the left medial rectus muscle. There were no cases of tumor recurrence that could be attributed to the procedure.

CONCLUSION

Our experience suggests that the Le Fort I osteotomy approach is a useful technique for the removal of extensive JNA invaded into pterygopalatine and infratemporal fossae. It has distinct advantages over traditional anterior or lateral approaches, providing a more direct vision, improved exposure, and cosmesis.

Authors+Show Affiliations

Department of Otorhinolaryngology, Xijing Hospital, The Fourth Military Medical University, Xi'an, People's Republic of China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18836867

Citation

Lin, Ying, et al. "Le Fort I Osteotomy for Extensive Juvenile Nasopharyngeal Angiofibroma: a Retrospective Study." Advances in Therapy, vol. 25, no. 10, 2008, pp. 1057-64.
Lin Y, Qiu JH, Qiao L, et al. Le Fort I osteotomy for extensive juvenile nasopharyngeal angiofibroma: a retrospective study. Adv Ther. 2008;25(10):1057-64.
Lin, Y., Qiu, J. H., Qiao, L., He, L. S., & Zha, D. J. (2008). Le Fort I osteotomy for extensive juvenile nasopharyngeal angiofibroma: a retrospective study. Advances in Therapy, 25(10), 1057-64. https://doi.org/10.1007/s12325-008-0104-0
Lin Y, et al. Le Fort I Osteotomy for Extensive Juvenile Nasopharyngeal Angiofibroma: a Retrospective Study. Adv Ther. 2008;25(10):1057-64. PubMed PMID: 18836867.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Le Fort I osteotomy for extensive juvenile nasopharyngeal angiofibroma: a retrospective study. AU - Lin,Ying, AU - Qiu,Jian-Hua, AU - Qiao,Li, AU - He,Li-Sheng, AU - Zha,Ding-Jun, PY - 2008/10/7/pubmed PY - 2009/3/10/medline PY - 2008/10/7/entrez SP - 1057 EP - 64 JF - Advances in therapy JO - Adv Ther VL - 25 IS - 10 N2 - INTRODUCTION: Juvenile nasopharyngeal angiofibroma (JNA) is a rare, nonencapsulated, benign neoplasm typically diagnosed in adolescent boys. Surgery is the usual treatment modality for JNA. The optimal surgical procedure should allow maximal exposure of the tumor for complete excision with minimum morbidity. One possible surgical approach is Le Fort I maxillary osteotomy. The aim of this study was to review our experience with the Le Fort I osteotomy and to investigate the feasibility of this approach for extensive JNA invaded into pterygopalatine and infratemporal fossae. METHODS: We retrospectively studied patients who had undergone JNA resection via the Le Fort I osteotomy approach from July 2000 to September 2007, considering tumor location and size, complications, and tumor recurrence associated with the surgical approach. RESULTS: Six patients of JNA (all boys; mean age, 15.5 years) were identified through the chart review. All the angiofibromas had extended into the pterygomaxillary space and infratemporal fossa. The mean follow-up for this cohort was 50.1 months. No intraoperative and postoperative complications were noted, except for slight diplopia in one patient due to injury of the left medial rectus muscle. There were no cases of tumor recurrence that could be attributed to the procedure. CONCLUSION: Our experience suggests that the Le Fort I osteotomy approach is a useful technique for the removal of extensive JNA invaded into pterygopalatine and infratemporal fossae. It has distinct advantages over traditional anterior or lateral approaches, providing a more direct vision, improved exposure, and cosmesis. SN - 0741-238X UR - https://www.unboundmedicine.com/medline/citation/18836867/Le_Fort_I_osteotomy_for_extensive_juvenile_nasopharyngeal_angiofibroma:_a_retrospective_study_ L2 - https://dx.doi.org/10.1007/s12325-008-0104-0 DB - PRIME DP - Unbound Medicine ER -