Tags

Type your tag names separated by a space and hit enter

New vernocuminosides from the stem barks of Vernonia cumingiana Benth.
Steroids. 2009 Jan; 74(1):51-61.S

Abstract

Seven new stigmastane-type steroidal glycosides, vernocuminosides A-G (1-7), have been isolated from the stem barks of Vernonia cumingiana Benth. The structural elucidation and stereochemistry determination were achieved by spectroscopic and chemical methods including 1D and 2D NMR ((1)H-(1)H COSY, HSQC, HMBC, and NOE) experiments, especially the employment of Snatzke's method expressed by the induced circular dichroism spectra. Anti-inflammatory activities and cytotoxicities of compounds 1-7 were evaluated.

Links

Publisher Full Text
Aggregator Full Text

Authors+Show Affiliations

Liu J
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education & Institute of Materia Medica, Beijing 100050, People's Republic of China.
Liu Y
No affiliation info available
Si Y
No affiliation info available
Yu S
No affiliation info available
Qu J
No affiliation info available
Xu S
No affiliation info available
Hu Y
No affiliation info available
Ma S
No affiliation info available

MeSH

AnimalsAnti-Inflammatory AgentsDrug Evaluation, PreclinicalGlucosidesGlucuronidaseLeukocytesPlant StemsPlatelet Activating FactorRatsSteroidsVernonia

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18840454

Citation

Liu, Jing, et al. "New Vernocuminosides From the Stem Barks of Vernonia Cumingiana Benth." Steroids, vol. 74, no. 1, 2009, pp. 51-61.
Liu J, Liu Y, Si Y, et al. New vernocuminosides from the stem barks of Vernonia cumingiana Benth. Steroids. 2009;74(1):51-61.
Liu, J., Liu, Y., Si, Y., Yu, S., Qu, J., Xu, S., Hu, Y., & Ma, S. (2009). New vernocuminosides from the stem barks of Vernonia cumingiana Benth. Steroids, 74(1), 51-61. https://doi.org/10.1016/j.steroids.2008.09.005
Liu J, et al. New Vernocuminosides From the Stem Barks of Vernonia Cumingiana Benth. Steroids. 2009;74(1):51-61. PubMed PMID: 18840454.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New vernocuminosides from the stem barks of Vernonia cumingiana Benth. AU - Liu,Jing, AU - Liu,Yunbao, AU - Si,Yikang, AU - Yu,Shishan, AU - Qu,Jing, AU - Xu,Song, AU - Hu,Youcai, AU - Ma,Shuanggang, Y1 - 2008/09/16/ PY - 2008/01/30/received PY - 2008/09/04/revised PY - 2008/09/05/accepted PY - 2008/10/9/entrez PY - 2008/10/9/pubmed PY - 2009/3/4/medline SP - 51 EP - 61 JF - Steroids JO - Steroids VL - 74 IS - 1 N2 - Seven new stigmastane-type steroidal glycosides, vernocuminosides A-G (1-7), have been isolated from the stem barks of Vernonia cumingiana Benth. The structural elucidation and stereochemistry determination were achieved by spectroscopic and chemical methods including 1D and 2D NMR ((1)H-(1)H COSY, HSQC, HMBC, and NOE) experiments, especially the employment of Snatzke's method expressed by the induced circular dichroism spectra. Anti-inflammatory activities and cytotoxicities of compounds 1-7 were evaluated. SN - 0039-128X UR - https://www.unboundmedicine.com/medline/citation/18840454/New_vernocuminosides_from_the_stem_barks_of_Vernonia_cumingiana_Benth_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0039-128X(08)00238-9 DB - PRIME DP - Unbound Medicine ER -