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[24-hour urinary oxalate excretion in healthy children and in children with calcium urolithiasis].
Pol Merkur Lekarski. 2008; 24 Suppl 4:76-9.PM

Abstract

Hyperoxaluria is one of the crucial risk factors for calcium stone formation.

AIM

Estimation of own reference range for 24-hour urinary oxalate (OX) excretion and evaluation of incidence of primary and secondary hyperoxaluria in children with calcium urolithiasis.

MATERIALS AND METHODS

The study comprised 128 healthy children aged 4-17,9 years and 137 children aged 3.7-18 years with calcium urolithiasis.

RESULTS

In healthy children, the mean 24-hour urinary OX excretion was 0.305 +/- 0.109 mmol/ 1.73 m2/ 24 h. An upper normal limit for urinary OX excretion was assumed at 0.474 mmol/1, 73 m2 / 24 h (95th percentile). Patients with stones had significantly higher urinary OX excretion (0.381 +/- 0.173 mmol / 1.73 m/ 24 h) in comparison to healthy children. Secondary hyperoxaluria was revealed in 37 (27%) children, whereas primary hyperoxaluria type I was diagnosed in only 1 (0.7%).

CONCLUSIONS

Secondary hyperoxaluria occurred in a significant percentage of children with calcium urolithiasis, predominantly in males, whereas primary hyperoxaluria is casuistic.

Authors+Show Affiliations

Klinika Nefrologii Dzieciecej Uniwersytetu Medycznego w Lublinie. sikoraprzem@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

pol

PubMed ID

18924510

Citation

Sikora, Przemysław, et al. "[24-hour Urinary Oxalate Excretion in Healthy Children and in Children With Calcium Urolithiasis]." Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego, vol. 24 Suppl 4, 2008, pp. 76-9.
Sikora P, Bieniaś B, Wawrzyszuk M, et al. [24-hour urinary oxalate excretion in healthy children and in children with calcium urolithiasis]. Pol Merkur Lekarski. 2008;24 Suppl 4:76-9.
Sikora, P., Bieniaś, B., Wawrzyszuk, M., & Zajaczkowska, M. (2008). [24-hour urinary oxalate excretion in healthy children and in children with calcium urolithiasis]. Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego, 24 Suppl 4, 76-9.
Sikora P, et al. [24-hour Urinary Oxalate Excretion in Healthy Children and in Children With Calcium Urolithiasis]. Pol Merkur Lekarski. 2008;24 Suppl 4:76-9. PubMed PMID: 18924510.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [24-hour urinary oxalate excretion in healthy children and in children with calcium urolithiasis]. AU - Sikora,Przemysław, AU - Bieniaś,Beata, AU - Wawrzyszuk,Mirosława, AU - Zajaczkowska,Małgorzata, PY - 2008/10/18/pubmed PY - 2008/10/31/medline PY - 2008/10/18/entrez SP - 76 EP - 9 JF - Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego JO - Pol. Merkur. Lekarski VL - 24 Suppl 4 N2 - UNLABELLED: Hyperoxaluria is one of the crucial risk factors for calcium stone formation. AIM: Estimation of own reference range for 24-hour urinary oxalate (OX) excretion and evaluation of incidence of primary and secondary hyperoxaluria in children with calcium urolithiasis. MATERIALS AND METHODS: The study comprised 128 healthy children aged 4-17,9 years and 137 children aged 3.7-18 years with calcium urolithiasis. RESULTS: In healthy children, the mean 24-hour urinary OX excretion was 0.305 +/- 0.109 mmol/ 1.73 m2/ 24 h. An upper normal limit for urinary OX excretion was assumed at 0.474 mmol/1, 73 m2 / 24 h (95th percentile). Patients with stones had significantly higher urinary OX excretion (0.381 +/- 0.173 mmol / 1.73 m/ 24 h) in comparison to healthy children. Secondary hyperoxaluria was revealed in 37 (27%) children, whereas primary hyperoxaluria type I was diagnosed in only 1 (0.7%). CONCLUSIONS: Secondary hyperoxaluria occurred in a significant percentage of children with calcium urolithiasis, predominantly in males, whereas primary hyperoxaluria is casuistic. SN - 1426-9686 UR - https://www.unboundmedicine.com/medline/citation/18924510/[24_hour_urinary_oxalate_excretion_in_healthy_children_and_in_children_with_calcium_urolithiasis]_ DB - PRIME DP - Unbound Medicine ER -