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Prevalence of exfoliation syndrome in central Sri Lanka: the Kandy Eye Study.
Br J Ophthalmol. 2008 Dec; 92(12):1595-8.BJ

Abstract

AIMS

To report the prevalence and correlates of exfoliation syndrome (XFS) in central, rural Sri Lanka.

METHODS

A population-based, cross-sectional ophthalmic survey of inhabitants 40 years of age and over from villages in the Kandy District was conducted. Selection was randomised using a cluster sampling process. 1721 eligible participants were identified, 1375 participated. A detailed ophthalmic history and examination including ocular biometry was made of each participant.

RESULTS

The prevalence of XFS was estimated to be 1.1% (95% CI 0.5 to 1.5%; 22 eyes). XFS was bilateral in eight subjects, unilateral in six subjects. Univariate analysis demonstrated a significant association between XFS and increasing age (p<0.001), increasing intraocular pressure (odds ratio 1.2; 95% CI 1.09 to 1.27; p<0.001), nuclear cataracts (odds ratio 1.92; 95% CI 1.47 to 2.51; p<0.001), visual impairment (odds ratio 9.72; 95% CI 3.01 to 31.44; p<0.001) and a history of hypertension (odds ratio 3.89; 95% CI 1.14 to 13.16; p = 0.030).

CONCLUSION

XFS in this Sri Lankan population was associated with advanced age, raised intraocular pressure, nuclear cataracts, hypertension and visual impairment.

Authors+Show Affiliations

South Australian Institute of Ophthalmology, Adelaide, 5000, South Australia, Australia. adam@rudkin.com.auNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18927228

Citation

Rudkin, A K., et al. "Prevalence of Exfoliation Syndrome in Central Sri Lanka: the Kandy Eye Study." The British Journal of Ophthalmology, vol. 92, no. 12, 2008, pp. 1595-8.
Rudkin AK, Edussuriya K, Sennanayake S, et al. Prevalence of exfoliation syndrome in central Sri Lanka: the Kandy Eye Study. Br J Ophthalmol. 2008;92(12):1595-8.
Rudkin, A. K., Edussuriya, K., Sennanayake, S., Senaratne, T., Selva, D., Sullivan, T. R., & Casson, R. J. (2008). Prevalence of exfoliation syndrome in central Sri Lanka: the Kandy Eye Study. The British Journal of Ophthalmology, 92(12), 1595-8. https://doi.org/10.1136/bjo.2008.146407
Rudkin AK, et al. Prevalence of Exfoliation Syndrome in Central Sri Lanka: the Kandy Eye Study. Br J Ophthalmol. 2008;92(12):1595-8. PubMed PMID: 18927228.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of exfoliation syndrome in central Sri Lanka: the Kandy Eye Study. AU - Rudkin,A K, AU - Edussuriya,K, AU - Sennanayake,S, AU - Senaratne,T, AU - Selva,D, AU - Sullivan,T R, AU - Casson,R J, Y1 - 2008/10/16/ PY - 2008/10/18/pubmed PY - 2009/1/8/medline PY - 2008/10/18/entrez SP - 1595 EP - 8 JF - The British journal of ophthalmology JO - Br J Ophthalmol VL - 92 IS - 12 N2 - AIMS: To report the prevalence and correlates of exfoliation syndrome (XFS) in central, rural Sri Lanka. METHODS: A population-based, cross-sectional ophthalmic survey of inhabitants 40 years of age and over from villages in the Kandy District was conducted. Selection was randomised using a cluster sampling process. 1721 eligible participants were identified, 1375 participated. A detailed ophthalmic history and examination including ocular biometry was made of each participant. RESULTS: The prevalence of XFS was estimated to be 1.1% (95% CI 0.5 to 1.5%; 22 eyes). XFS was bilateral in eight subjects, unilateral in six subjects. Univariate analysis demonstrated a significant association between XFS and increasing age (p<0.001), increasing intraocular pressure (odds ratio 1.2; 95% CI 1.09 to 1.27; p<0.001), nuclear cataracts (odds ratio 1.92; 95% CI 1.47 to 2.51; p<0.001), visual impairment (odds ratio 9.72; 95% CI 3.01 to 31.44; p<0.001) and a history of hypertension (odds ratio 3.89; 95% CI 1.14 to 13.16; p = 0.030). CONCLUSION: XFS in this Sri Lankan population was associated with advanced age, raised intraocular pressure, nuclear cataracts, hypertension and visual impairment. SN - 1468-2079 UR - https://www.unboundmedicine.com/medline/citation/18927228/Prevalence_of_exfoliation_syndrome_in_central_Sri_Lanka:_the_Kandy_Eye_Study_ L2 - http://bjo.bmj.com/cgi/pmidlookup?view=long&amp;pmid=18927228 DB - PRIME DP - Unbound Medicine ER -