Tags

Type your tag names separated by a space and hit enter

Severity scoring of atopic dermatitis: a comparison of two scoring systems.
Allergol Immunopathol (Madr) 2008 Jul-Aug; 36(4):205-11AI

Abstract

BACKGROUND

Atopic dermatitis (AD) is a chronic inflammatory pruritic skin heterogeneous disease, which does not have an objective tool able to permit comparison between patients and to monitor changes due to a specific treatment. Several assessment methods have been developed to evaluate the AD.

OBJECTIVES

The aim of this study was to investigate the agreement between two observers in the assessment of the severity of AD applying SCORAD index and EASI in infants and young children with AD. The variations of parameters that compose each score, as well as the inter-observer variation for both scores, were also studied.

METHODS

We evaluated 42 infants and young children admitted and followed in a paediatric allergy centre (UNIFESP-EPM). All children met the diagnostic criteria for clinical AD established by Hanifin and Rajka. Two investigators graded the severity of AD, applying the SCORAD index and EASI. The two scoring systems assessed the variation between baseline evaluation and one month after treatment.

RESULTS

Significant correlations were observed comparing both scores for each physician and each evaluation. There were no differences between the mean SCORAD and EASI scores for each physician, in the two evaluations. There was a significant decrease in the mean total SCORAD and EASI score and its components, except for the item Upper Extremities EASI CONCLUSION: Both scoring systems for AD are valid, reproducible and responsive in monitoring AD patients. Further studies will be necessary to investigate the development of AD and the best evaluation. SCORAD showed itself to be an excellent score to detect the development of AD, whereas the EASI are suitable to follow up in drug-effect studies of AD for research purposes.

Authors+Show Affiliations

Department of Pediatrics. Federal University of São Paulo-Escola Paulista de Medicina. São Paulo. Brasil. alergia.reumato@terra.com.brNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

18928687

Citation

Rullo, V E V., et al. "Severity Scoring of Atopic Dermatitis: a Comparison of Two Scoring Systems." Allergologia Et Immunopathologia, vol. 36, no. 4, 2008, pp. 205-11.
Rullo VE, Segato A, Kirsh A, et al. Severity scoring of atopic dermatitis: a comparison of two scoring systems. Allergol Immunopathol (Madr). 2008;36(4):205-11.
Rullo, V. E., Segato, A., Kirsh, A., & Sole, D. (2008). Severity scoring of atopic dermatitis: a comparison of two scoring systems. Allergologia Et Immunopathologia, 36(4), pp. 205-11.
Rullo VE, et al. Severity Scoring of Atopic Dermatitis: a Comparison of Two Scoring Systems. Allergol Immunopathol (Madr). 2008;36(4):205-11. PubMed PMID: 18928687.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Severity scoring of atopic dermatitis: a comparison of two scoring systems. AU - Rullo,V E V, AU - Segato,A, AU - Kirsh,A, AU - Sole,D, PY - 2008/10/22/pubmed PY - 2009/2/20/medline PY - 2008/10/22/entrez SP - 205 EP - 11 JF - Allergologia et immunopathologia JO - Allergol Immunopathol (Madr) VL - 36 IS - 4 N2 - BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory pruritic skin heterogeneous disease, which does not have an objective tool able to permit comparison between patients and to monitor changes due to a specific treatment. Several assessment methods have been developed to evaluate the AD. OBJECTIVES: The aim of this study was to investigate the agreement between two observers in the assessment of the severity of AD applying SCORAD index and EASI in infants and young children with AD. The variations of parameters that compose each score, as well as the inter-observer variation for both scores, were also studied. METHODS: We evaluated 42 infants and young children admitted and followed in a paediatric allergy centre (UNIFESP-EPM). All children met the diagnostic criteria for clinical AD established by Hanifin and Rajka. Two investigators graded the severity of AD, applying the SCORAD index and EASI. The two scoring systems assessed the variation between baseline evaluation and one month after treatment. RESULTS: Significant correlations were observed comparing both scores for each physician and each evaluation. There were no differences between the mean SCORAD and EASI scores for each physician, in the two evaluations. There was a significant decrease in the mean total SCORAD and EASI score and its components, except for the item Upper Extremities EASI CONCLUSION: Both scoring systems for AD are valid, reproducible and responsive in monitoring AD patients. Further studies will be necessary to investigate the development of AD and the best evaluation. SCORAD showed itself to be an excellent score to detect the development of AD, whereas the EASI are suitable to follow up in drug-effect studies of AD for research purposes. SN - 0301-0546 UR - https://www.unboundmedicine.com/medline/citation/18928687/Severity_scoring_of_atopic_dermatitis:_a_comparison_of_two_scoring_systems_ L2 - http://www.elsevier.es/en/linksolver/ft/ivp/0301-0546/36/205 DB - PRIME DP - Unbound Medicine ER -