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Changes in amino acid concentration in plasma and type I and type II fibres during resistance exercise and recovery in human subjects.
Amino Acids. 2009 Oct; 37(4):629-36.AA

Abstract

Eight male subjects performed leg press exercise, 4 x 10 repetitions at 80% of their maximum. Venous blood samples were taken before, during exercise and repeatedly during 2 h of recovery. From four subjects, biopsies were taken from the vastus lateralis muscle prior to, immediately after and following one and 2 h of recovery. Samples were freeze-dried, individual muscle fibres were dissected out and identified as type I or type II. Resistance exercise led to pronounced reductions in the glutamate concentration in both type I (32%) and type II fibres (70%). Alanine concentration was elevated 60-75% in both fibre types and 29% in plasma. Glutamine concentration remained unchanged after exercise; although 2 h later the concentrations in both types of fibres were reduced 30-35%. Two hours after exercise, the plasma levels of glutamate and six of the essential amino acids, including the branched-chain amino acids were reduced 5-30%. The data suggest that glutamate acts as an important intermediate in muscle energy metabolism during resistance exercise, especially in type II fibres.

Authors+Show Affiliations

Swedish School of Sport and Health Sciences, Box 5626, 114 86, Stockholm, Sweden. eva.blomstrand@gih.seNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18931969

Citation

Blomstrand, Eva, and Birgitta Essén-Gustavsson. "Changes in Amino Acid Concentration in Plasma and Type I and Type II Fibres During Resistance Exercise and Recovery in Human Subjects." Amino Acids, vol. 37, no. 4, 2009, pp. 629-36.
Blomstrand E, Essén-Gustavsson B. Changes in amino acid concentration in plasma and type I and type II fibres during resistance exercise and recovery in human subjects. Amino Acids. 2009;37(4):629-36.
Blomstrand, E., & Essén-Gustavsson, B. (2009). Changes in amino acid concentration in plasma and type I and type II fibres during resistance exercise and recovery in human subjects. Amino Acids, 37(4), 629-36. https://doi.org/10.1007/s00726-008-0182-y
Blomstrand E, Essén-Gustavsson B. Changes in Amino Acid Concentration in Plasma and Type I and Type II Fibres During Resistance Exercise and Recovery in Human Subjects. Amino Acids. 2009;37(4):629-36. PubMed PMID: 18931969.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Changes in amino acid concentration in plasma and type I and type II fibres during resistance exercise and recovery in human subjects. AU - Blomstrand,Eva, AU - Essén-Gustavsson,Birgitta, Y1 - 2008/10/19/ PY - 2008/07/08/received PY - 2008/09/11/accepted PY - 2008/10/22/pubmed PY - 2010/1/15/medline PY - 2008/10/22/entrez SP - 629 EP - 36 JF - Amino acids JO - Amino Acids VL - 37 IS - 4 N2 - Eight male subjects performed leg press exercise, 4 x 10 repetitions at 80% of their maximum. Venous blood samples were taken before, during exercise and repeatedly during 2 h of recovery. From four subjects, biopsies were taken from the vastus lateralis muscle prior to, immediately after and following one and 2 h of recovery. Samples were freeze-dried, individual muscle fibres were dissected out and identified as type I or type II. Resistance exercise led to pronounced reductions in the glutamate concentration in both type I (32%) and type II fibres (70%). Alanine concentration was elevated 60-75% in both fibre types and 29% in plasma. Glutamine concentration remained unchanged after exercise; although 2 h later the concentrations in both types of fibres were reduced 30-35%. Two hours after exercise, the plasma levels of glutamate and six of the essential amino acids, including the branched-chain amino acids were reduced 5-30%. The data suggest that glutamate acts as an important intermediate in muscle energy metabolism during resistance exercise, especially in type II fibres. SN - 1438-2199 UR - https://www.unboundmedicine.com/medline/citation/18931969/Changes_in_amino_acid_concentration_in_plasma_and_type_I_and_type_II_fibres_during_resistance_exercise_and_recovery_in_human_subjects_ L2 - https://dx.doi.org/10.1007/s00726-008-0182-y DB - PRIME DP - Unbound Medicine ER -