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Evaluation of a phosphate management protocol to achieve optimum serum phosphate levels in hemodialysis patients.
J Ren Nutr. 2008 Nov; 18(6):521-9.JR

Abstract

OBJECTIVE

To evaluate the effectiveness of a protocol designed to optimize serum phosphate levels in patients undergoing regular hemodialysis (HD).

DESIGN

Randomized, controlled trial.

SETTING

Hemodialysis units at Barts and the London NHS Trust and satellite units.

PATIENTS

Thirty-four clinically stable adults undergoing regular HD with a serum phosphate level >1.8 mmol/L on at least one occasion within 4 months of starting the study.

INTERVENTION

Management of serum phosphate using a specially designed phosphate management protocol during a 4-month study period implemented by a renal dietitian and renal pharmacist compared with standard practice.

MAIN OUTCOME MEASURE

Change in serum phosphate levels in both groups after 4 months.

RESULTS

Patients managed using the phosphate management protocol had a significantly greater reduction in serum phosphate levels compared with patients receiving standard practice (-0.22 +/- 0.67 mmol/L vs. +0.19 +/- 0.32 mmol/L, P = 0.03).

CONCLUSION

The phosphate management protocol was effective, and its implementation was associated with significantly better serum phosphate control in patients undergoing regular HD.

Authors+Show Affiliations

Department of Health and Human Sciences, Barts and the London NHS Trust, London Metropolitan University, London, UK.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18940656

Citation

Yokum, Dawn, et al. "Evaluation of a Phosphate Management Protocol to Achieve Optimum Serum Phosphate Levels in Hemodialysis Patients." Journal of Renal Nutrition : the Official Journal of the Council On Renal Nutrition of the National Kidney Foundation, vol. 18, no. 6, 2008, pp. 521-9.
Yokum D, Glass G, Cheung CF, et al. Evaluation of a phosphate management protocol to achieve optimum serum phosphate levels in hemodialysis patients. J Ren Nutr. 2008;18(6):521-9.
Yokum, D., Glass, G., Cheung, C. F., Cunningham, J., Fan, S., & Madden, A. M. (2008). Evaluation of a phosphate management protocol to achieve optimum serum phosphate levels in hemodialysis patients. Journal of Renal Nutrition : the Official Journal of the Council On Renal Nutrition of the National Kidney Foundation, 18(6), 521-9. https://doi.org/10.1053/j.jrn.2008.05.003
Yokum D, et al. Evaluation of a Phosphate Management Protocol to Achieve Optimum Serum Phosphate Levels in Hemodialysis Patients. J Ren Nutr. 2008;18(6):521-9. PubMed PMID: 18940656.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of a phosphate management protocol to achieve optimum serum phosphate levels in hemodialysis patients. AU - Yokum,Dawn, AU - Glass,Georgina, AU - Cheung,Ching Fun, AU - Cunningham,John, AU - Fan,Stanley, AU - Madden,Angela M, PY - 2007/09/23/received PY - 2008/10/23/pubmed PY - 2009/2/21/medline PY - 2008/10/23/entrez SP - 521 EP - 9 JF - Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation JO - J Ren Nutr VL - 18 IS - 6 N2 - OBJECTIVE: To evaluate the effectiveness of a protocol designed to optimize serum phosphate levels in patients undergoing regular hemodialysis (HD). DESIGN: Randomized, controlled trial. SETTING: Hemodialysis units at Barts and the London NHS Trust and satellite units. PATIENTS: Thirty-four clinically stable adults undergoing regular HD with a serum phosphate level >1.8 mmol/L on at least one occasion within 4 months of starting the study. INTERVENTION: Management of serum phosphate using a specially designed phosphate management protocol during a 4-month study period implemented by a renal dietitian and renal pharmacist compared with standard practice. MAIN OUTCOME MEASURE: Change in serum phosphate levels in both groups after 4 months. RESULTS: Patients managed using the phosphate management protocol had a significantly greater reduction in serum phosphate levels compared with patients receiving standard practice (-0.22 +/- 0.67 mmol/L vs. +0.19 +/- 0.32 mmol/L, P = 0.03). CONCLUSION: The phosphate management protocol was effective, and its implementation was associated with significantly better serum phosphate control in patients undergoing regular HD. SN - 1532-8503 UR - https://www.unboundmedicine.com/medline/citation/18940656/Evaluation_of_a_phosphate_management_protocol_to_achieve_optimum_serum_phosphate_levels_in_hemodialysis_patients_ DB - PRIME DP - Unbound Medicine ER -