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Effects of exercise training on exercise aerobic capacity and quality of life in hemodialysis patients.
J Nephrol. 2008 Sep-Oct; 21(5):738-43.JN

Abstract

BACKGROUND

Physical and aerobic capacity are extremely limited in dialysis patients, but it is uncertain whether or not exercise training is safe or has beneficial effects. This study aimed to assess the effects of exercise training on functional capacity and quality of life of hemodialysis patients.

METHODS

Ten hemodialysis patients (7 men, 3 women, aged 37 +/- 7 years) free from severe comorbidities were recruited. They underwent training sessions (up to 90 minutes of submaximal exercise) twice a week, on nondialysis days, for 12 months. At baseline and after the physical training program, all patients underwent biochemistry, cardiopulmonary exercise test, echocardiography and a self-rated health test (SF-36).

RESULTS

At baseline, dialysis patients showed impaired VO2 uptake (20.6 +/- 5.0 ml/kg/min vs. 34.2 +/- 6.0 ml/kg/min, p<0.001) and peak working capacity (115 +/- 36 W vs. 192 +/- 46.7 W, p<0.001) compared with normal controls. Following the training program, both peak VO2 (20.4 +/- 4.9 ml/kg/min vs. 25.1 +/- 6.5 ml/kg/min, p<0.05), VO2 at anaerobic threshold (12.8 +/- 1.9 ml/kg/min vs. 15.1 +/- 3.8 ml/kg/min, p<0.05), peak working capacity (113 +/- 33 W vs. 134 +/- 37 W, p<0.01) and SF-36 scores improved. No side effects related to intervention occurred.

CONCLUSIONS

Dialysis patients showed impaired muscular exercise capacity, but 12 months of moderate exercise training was able to improve their physical function, aerobic capacity and quality of life. Our study suggests that mild, regular physical activity should be recommended and encouraged as an important aspect of the care of selected dialysis patients.

Authors+Show Affiliations

Capitanini A
Nephrology Unit, Pescia Hospital, Pescia - Italy. drcapitanini@excite.it
Cupisti A
No affiliation info available
Mochi N
No affiliation info available
Rossini D
No affiliation info available
Lupi A
No affiliation info available
Michelotti G
No affiliation info available
Rossi A
No affiliation info available

MeSH

AdultAnaerobic ThresholdExercise TestExercise TherapyExercise ToleranceFemaleHeart RateHumansKidney Failure, ChronicMaleOxygen ConsumptionQuality of LifeRenal Dialysis

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18949729

Citation

Capitanini, Alessandro, et al. "Effects of Exercise Training On Exercise Aerobic Capacity and Quality of Life in Hemodialysis Patients." Journal of Nephrology, vol. 21, no. 5, 2008, pp. 738-43.
Capitanini A, Cupisti A, Mochi N, et al. Effects of exercise training on exercise aerobic capacity and quality of life in hemodialysis patients. J Nephrol. 2008;21(5):738-43.
Capitanini, A., Cupisti, A., Mochi, N., Rossini, D., Lupi, A., Michelotti, G., & Rossi, A. (2008). Effects of exercise training on exercise aerobic capacity and quality of life in hemodialysis patients. Journal of Nephrology, 21(5), 738-43.
Capitanini A, et al. Effects of Exercise Training On Exercise Aerobic Capacity and Quality of Life in Hemodialysis Patients. J Nephrol. 2008 Sep-Oct;21(5):738-43. PubMed PMID: 18949729.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of exercise training on exercise aerobic capacity and quality of life in hemodialysis patients. AU - Capitanini,Alessandro, AU - Cupisti,Adamasco, AU - Mochi,Nicola, AU - Rossini,Duccio, AU - Lupi,Aldo, AU - Michelotti,Giampaolo, AU - Rossi,Arturo, PY - 2008/10/25/pubmed PY - 2009/4/1/medline PY - 2008/10/25/entrez SP - 738 EP - 43 JF - Journal of nephrology JO - J Nephrol VL - 21 IS - 5 N2 - BACKGROUND: Physical and aerobic capacity are extremely limited in dialysis patients, but it is uncertain whether or not exercise training is safe or has beneficial effects. This study aimed to assess the effects of exercise training on functional capacity and quality of life of hemodialysis patients. METHODS: Ten hemodialysis patients (7 men, 3 women, aged 37 +/- 7 years) free from severe comorbidities were recruited. They underwent training sessions (up to 90 minutes of submaximal exercise) twice a week, on nondialysis days, for 12 months. At baseline and after the physical training program, all patients underwent biochemistry, cardiopulmonary exercise test, echocardiography and a self-rated health test (SF-36). RESULTS: At baseline, dialysis patients showed impaired VO2 uptake (20.6 +/- 5.0 ml/kg/min vs. 34.2 +/- 6.0 ml/kg/min, p<0.001) and peak working capacity (115 +/- 36 W vs. 192 +/- 46.7 W, p<0.001) compared with normal controls. Following the training program, both peak VO2 (20.4 +/- 4.9 ml/kg/min vs. 25.1 +/- 6.5 ml/kg/min, p<0.05), VO2 at anaerobic threshold (12.8 +/- 1.9 ml/kg/min vs. 15.1 +/- 3.8 ml/kg/min, p<0.05), peak working capacity (113 +/- 33 W vs. 134 +/- 37 W, p<0.01) and SF-36 scores improved. No side effects related to intervention occurred. CONCLUSIONS: Dialysis patients showed impaired muscular exercise capacity, but 12 months of moderate exercise training was able to improve their physical function, aerobic capacity and quality of life. Our study suggests that mild, regular physical activity should be recommended and encouraged as an important aspect of the care of selected dialysis patients. SN - 1121-8428 UR - https://www.unboundmedicine.com/medline/citation/18949729/Effects_of_exercise_training_on_exercise_aerobic_capacity_and_quality_of_life_in_hemodialysis_patients_ L2 - https://medlineplus.gov/dialysis.html DB - PRIME DP - Unbound Medicine ER -