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Antioxidant C-glucosylxanthones from the leaves of Arrabidaea patellifera.
J Nat Prod. 2008 Nov; 71(11):1887-90.JN

Abstract

Chemical investigation of the methanol extract from the leaves of Arrabidaea patellifera, a Bignoniaceae from Panama, afforded mangiferin, isomangiferin, and six new derivatives (3'-O-p-hydroxybenzoylmangiferin, 3'-O-trans-coumaroylmangiferin, 6'-O-trans-coumaroylmangiferin, 3'-O-trans-cinnamoylmangiferin, 3'-O-trans-caffeoylmangiferin, and 3'-O-benzoylmangiferin). All these compounds had antioxidant and radical-scavenging activities, and four of them were relatively active in vitro against Plasmodium falciparum. The structures were determined by spectrometric and chemical methods, including 1D and 2D NMR experiments and MS analysis.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Martin F
Laboratory of Pharmacognosy and Phytochemistry, School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Quai Ernest-Ansermet 30, CH-1211 Geneva 4, Switzerland.
Hay AE
No affiliation info available
Cressend D
No affiliation info available
Reist M
No affiliation info available
Vivas L
No affiliation info available
Gupta MP
No affiliation info available
Carrupt PA
No affiliation info available
Hostettmann K
No affiliation info available

MeSH

AntimalarialsAntioxidantsBignoniaceaeBiphenyl CompoundsFree Radical ScavengersNuclear Magnetic Resonance, BiomolecularPanamaPicratesPlant LeavesPlasmodium falciparumXanthones

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18950229

Citation

Martin, Frédéric, et al. "Antioxidant C-glucosylxanthones From the Leaves of Arrabidaea Patellifera." Journal of Natural Products, vol. 71, no. 11, 2008, pp. 1887-90.
Martin F, Hay AE, Cressend D, et al. Antioxidant C-glucosylxanthones from the leaves of Arrabidaea patellifera. J Nat Prod. 2008;71(11):1887-90.
Martin, F., Hay, A. E., Cressend, D., Reist, M., Vivas, L., Gupta, M. P., Carrupt, P. A., & Hostettmann, K. (2008). Antioxidant C-glucosylxanthones from the leaves of Arrabidaea patellifera. Journal of Natural Products, 71(11), 1887-90. https://doi.org/10.1021/np800406q
Martin F, et al. Antioxidant C-glucosylxanthones From the Leaves of Arrabidaea Patellifera. J Nat Prod. 2008;71(11):1887-90. PubMed PMID: 18950229.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant C-glucosylxanthones from the leaves of Arrabidaea patellifera. AU - Martin,Frédéric, AU - Hay,Anne-Emmanuelle, AU - Cressend,Delphine, AU - Reist,Marianne, AU - Vivas,Livia, AU - Gupta,Mahabir P, AU - Carrupt,Pierre-Alain, AU - Hostettmann,Kurt, Y1 - 2008/10/25/ PY - 2008/10/28/pubmed PY - 2011/12/13/medline PY - 2008/10/28/entrez SP - 1887 EP - 90 JF - Journal of natural products JO - J Nat Prod VL - 71 IS - 11 N2 - Chemical investigation of the methanol extract from the leaves of Arrabidaea patellifera, a Bignoniaceae from Panama, afforded mangiferin, isomangiferin, and six new derivatives (3'-O-p-hydroxybenzoylmangiferin, 3'-O-trans-coumaroylmangiferin, 6'-O-trans-coumaroylmangiferin, 3'-O-trans-cinnamoylmangiferin, 3'-O-trans-caffeoylmangiferin, and 3'-O-benzoylmangiferin). All these compounds had antioxidant and radical-scavenging activities, and four of them were relatively active in vitro against Plasmodium falciparum. The structures were determined by spectrometric and chemical methods, including 1D and 2D NMR experiments and MS analysis. SN - 1520-6025 UR - https://www.unboundmedicine.com/medline/citation/18950229/Antioxidant_C_glucosylxanthones_from_the_leaves_of_Arrabidaea_patellifera_ L2 - https://doi.org/10.1021/np800406q DB - PRIME DP - Unbound Medicine ER -