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Intake of paracetamol and risk of asthma in adults.
J Asthma 2008; 45(8):675-6JA

Abstract

Intake of paracetamol has been associated with development of asthma. The aim of this study was to address a possible association between intake of paracetamol and risk of adult-onset asthma. Using a multidisciplinary postal questionnaire survey concerning health and lifestyle we prospectively studied 19,349 adult twins enrolled in the nationwide Danish Twin Registry. There was a higher prevalence of new-onset asthma in subjects who reported frequent intake of paracetamol at baseline compared with subjects without this determinant (12.0% vs. 4.3%), OR = 3.03 (1.51-6.11), p = 0.005. The result remained significant after adjusting for sex, age, smoking, BMI, hay fever, eczema, and intake of medications other than paracetamol, OR = 2.16 (1.03-4.53), p = 0.041. Frequent intake of paracetamol is an independent risk factor for adult-onset asthma.

Authors+Show Affiliations

Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark. sft@city.dkNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Twin Study

Language

eng

PubMed ID

18951259

Citation

Thomsen, Simon Francis, et al. "Intake of Paracetamol and Risk of Asthma in Adults." The Journal of Asthma : Official Journal of the Association for the Care of Asthma, vol. 45, no. 8, 2008, pp. 675-6.
Thomsen SF, Kyvik KO, Skadhauge L, et al. Intake of paracetamol and risk of asthma in adults. J Asthma. 2008;45(8):675-6.
Thomsen, S. F., Kyvik, K. O., Skadhauge, L., Steffensen, I., & Backer, V. (2008). Intake of paracetamol and risk of asthma in adults. The Journal of Asthma : Official Journal of the Association for the Care of Asthma, 45(8), pp. 675-6. doi:10.1080/02770900802165998.
Thomsen SF, et al. Intake of Paracetamol and Risk of Asthma in Adults. J Asthma. 2008;45(8):675-6. PubMed PMID: 18951259.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intake of paracetamol and risk of asthma in adults. AU - Thomsen,Simon Francis, AU - Kyvik,Kirsten Ohm, AU - Skadhauge,Lars, AU - Steffensen,Ida, AU - Backer,Vibeke, PY - 2008/10/28/pubmed PY - 2008/11/13/medline PY - 2008/10/28/entrez SP - 675 EP - 6 JF - The Journal of asthma : official journal of the Association for the Care of Asthma JO - J Asthma VL - 45 IS - 8 N2 - Intake of paracetamol has been associated with development of asthma. The aim of this study was to address a possible association between intake of paracetamol and risk of adult-onset asthma. Using a multidisciplinary postal questionnaire survey concerning health and lifestyle we prospectively studied 19,349 adult twins enrolled in the nationwide Danish Twin Registry. There was a higher prevalence of new-onset asthma in subjects who reported frequent intake of paracetamol at baseline compared with subjects without this determinant (12.0% vs. 4.3%), OR = 3.03 (1.51-6.11), p = 0.005. The result remained significant after adjusting for sex, age, smoking, BMI, hay fever, eczema, and intake of medications other than paracetamol, OR = 2.16 (1.03-4.53), p = 0.041. Frequent intake of paracetamol is an independent risk factor for adult-onset asthma. SN - 1532-4303 UR - https://www.unboundmedicine.com/medline/citation/18951259/Intake_of_paracetamol_and_risk_of_asthma_in_adults_ L2 - http://www.tandfonline.com/doi/full/10.1080/02770900802165998 DB - PRIME DP - Unbound Medicine ER -