Tags

Type your tag names separated by a space and hit enter

Highly enantioselective aza-Henry reaction of ketoimines catalyzed by chiral N,N'-dioxide-copper(I) complexes.
Org Lett. 2008 Nov 20; 10(22):5305-8.OL

Abstract

The first example of catalytic enantioselective aza-Henry reaction of ketoimines has been realized using a simple chiral N,N'-dioxide-Cu(I) complex as catalyst. It performs well over a range of substrates to give the corresponding products in moderate to good yields (up to 83%) with high enantioselectivities (up to 96% ee).

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Tan C
Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, PR China.
Liu X
No affiliation info available
Wang L
No affiliation info available
Wang J
No affiliation info available
Feng X
No affiliation info available

MeSH

CatalysisCopperIminesNitrogen DioxideStereoisomerismSubstrate Specificity

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18954056

Citation

Tan, Cheng, et al. "Highly Enantioselective aza-Henry Reaction of Ketoimines Catalyzed By Chiral N,N'-dioxide-copper(I) Complexes." Organic Letters, vol. 10, no. 22, 2008, pp. 5305-8.
Tan C, Liu X, Wang L, et al. Highly enantioselective aza-Henry reaction of ketoimines catalyzed by chiral N,N'-dioxide-copper(I) complexes. Org Lett. 2008;10(22):5305-8.
Tan, C., Liu, X., Wang, L., Wang, J., & Feng, X. (2008). Highly enantioselective aza-Henry reaction of ketoimines catalyzed by chiral N,N'-dioxide-copper(I) complexes. Organic Letters, 10(22), 5305-8. https://doi.org/10.1021/ol802236h
Tan C, et al. Highly Enantioselective aza-Henry Reaction of Ketoimines Catalyzed By Chiral N,N'-dioxide-copper(I) Complexes. Org Lett. 2008 Nov 20;10(22):5305-8. PubMed PMID: 18954056.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Highly enantioselective aza-Henry reaction of ketoimines catalyzed by chiral N,N'-dioxide-copper(I) complexes. AU - Tan,Cheng, AU - Liu,Xiaohua, AU - Wang,Liwei, AU - Wang,Jun, AU - Feng,Xiaoming, Y1 - 2008/10/28/ PY - 2008/10/29/pubmed PY - 2008/12/17/medline PY - 2008/10/29/entrez SP - 5305 EP - 8 JF - Organic letters JO - Org Lett VL - 10 IS - 22 N2 - The first example of catalytic enantioselective aza-Henry reaction of ketoimines has been realized using a simple chiral N,N'-dioxide-Cu(I) complex as catalyst. It performs well over a range of substrates to give the corresponding products in moderate to good yields (up to 83%) with high enantioselectivities (up to 96% ee). SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/18954056/Highly_enantioselective_aza_Henry_reaction_of_ketoimines_catalyzed_by_chiral_NN'_dioxide_copper_I__complexes_ DB - PRIME DP - Unbound Medicine ER -