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Microbial metabolites of 8-prenylnaringenin, an estrogenic prenylflavanone.
Arch Pharm Res. 2008 Oct; 31(10):1241-6.AP

Abstract

Microbial metabolism studies of the phyto-estrogen (+/-)-8-prenylnaringenin (8-PN) (1) has led to the isolation of three pairs of metabolites (2-4). The structures of these compounds were identified as 5,4'-dihydroxy-7,8-[2-(1-hydroxy-1-methylethyl)-2,3-dihydrofurano]flavanones (2), 8-prenylnaringenin 7-O-beta-D-glucopyranosides (3), and 8-prenylnaringenin 7-O-beta-D-(6'''-O-alpha-hydroxypropionyl)-glucopyranosides (4) on the basis of the spectroscopic analysis.

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Authors+Show Affiliations

Kim HJ
College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 500-757, Korea.
Kim SH
No affiliation info available
Kang BY
No affiliation info available
Lee IS
No affiliation info available

MeSH

BacteriaCarbohydrate ConformationChromatography, High Pressure LiquidChromatography, Thin LayerCunninghamellaFermentationFlavanonesFungiHumulusHydrolysisMagnetic Resonance SpectroscopyMucorPhytoestrogensRhizopusSpectrophotometry, InfraredSpectrophotometry, Ultraviolet

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18958413

Citation

Kim, Hyun Jung, et al. "Microbial Metabolites of 8-prenylnaringenin, an Estrogenic Prenylflavanone." Archives of Pharmacal Research, vol. 31, no. 10, 2008, pp. 1241-6.
Kim HJ, Kim SH, Kang BY, et al. Microbial metabolites of 8-prenylnaringenin, an estrogenic prenylflavanone. Arch Pharm Res. 2008;31(10):1241-6.
Kim, H. J., Kim, S. H., Kang, B. Y., & Lee, I. S. (2008). Microbial metabolites of 8-prenylnaringenin, an estrogenic prenylflavanone. Archives of Pharmacal Research, 31(10), 1241-6. https://doi.org/10.1007/s12272-001-2102-5
Kim HJ, et al. Microbial Metabolites of 8-prenylnaringenin, an Estrogenic Prenylflavanone. Arch Pharm Res. 2008;31(10):1241-6. PubMed PMID: 18958413.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Microbial metabolites of 8-prenylnaringenin, an estrogenic prenylflavanone. AU - Kim,Hyun Jung, AU - Kim,So-Hyun, AU - Kang,Bok Yun, AU - Lee,Ik-Soo, Y1 - 2008/10/29/ PY - 2008/08/02/received PY - 2008/10/10/accepted PY - 2008/10/10/revised PY - 2008/10/30/pubmed PY - 2008/12/17/medline PY - 2008/10/30/entrez SP - 1241 EP - 6 JF - Archives of pharmacal research JO - Arch Pharm Res VL - 31 IS - 10 N2 - Microbial metabolism studies of the phyto-estrogen (+/-)-8-prenylnaringenin (8-PN) (1) has led to the isolation of three pairs of metabolites (2-4). The structures of these compounds were identified as 5,4'-dihydroxy-7,8-[2-(1-hydroxy-1-methylethyl)-2,3-dihydrofurano]flavanones (2), 8-prenylnaringenin 7-O-beta-D-glucopyranosides (3), and 8-prenylnaringenin 7-O-beta-D-(6'''-O-alpha-hydroxypropionyl)-glucopyranosides (4) on the basis of the spectroscopic analysis. SN - 0253-6269 UR - https://www.unboundmedicine.com/medline/citation/18958413/Microbial_metabolites_of_8_prenylnaringenin_an_estrogenic_prenylflavanone_ L2 - https://dx.doi.org/10.1007/s12272-001-2102-5 DB - PRIME DP - Unbound Medicine ER -