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Mycoplasma pneumoniae-associated mucositis with minimal skin manifestations.
Am J Clin Dermatol. 2008; 9(6):399-403.AJ

Abstract

Mycoplasma pneumoniae-associated mucositis is a rarely described complication of M. pneumoniae infection presenting with ocular, oral, and genital involvement but without the typical skin lesions seen in Stevens-Johnson syndrome. A 27-year-old man with a past history of asthma presented at the emergency room with a 1-week history of cough (initially non-productive but subsequently associated with non-bloody mucopurulent sputum), fever, myalgias, headache, and progressive dyspnea. Two days before admission he had commenced amoxicillin/clavulanic acid with no improvement. The patient reported bilateral conjunctival injection and hemorrhagic ulcers on the lips commencing the day prior to admission. Physical examination revealed fever (39 degrees C), bilateral exudative conjunctivitis, painful hemorrhagic ulcers on the lips, tongue, and oral mucosa, small scrotal erosions, erythema of the penile meatus, and small erythematous bullae on the dorsum of each hand; subsequently, the patient developed bullae at the venipuncture site on his right arm. Laboratory tests revealed positive IgM serology for M. pneumoniae, with titer elevation. The patient was successfully treated with levofloxacin and prednisolone. Our case appears to be the first adult patient described with M. pneumoniae-associated mucositis, which has previously been reported only in pediatric patients. This is also the first reported instance of a case of M. pneumoniae-associated mucositis treated with levofloxacin and prednisolone. M. pneumoniae infection should be considered in all cases of mucositis, and treatment of this condition with levofloxacin and prednisolone seems to be effective.

Authors+Show Affiliations

Unit of Internal Medicine 1 - Hospital Curry Cabral, Lisbon, Portugal. jffcoelho@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

18973408

Citation

Figueira-Coelho, João, et al. "Mycoplasma Pneumoniae-associated Mucositis With Minimal Skin Manifestations." American Journal of Clinical Dermatology, vol. 9, no. 6, 2008, pp. 399-403.
Figueira-Coelho J, Lourenço S, Pires AC, et al. Mycoplasma pneumoniae-associated mucositis with minimal skin manifestations. Am J Clin Dermatol. 2008;9(6):399-403.
Figueira-Coelho, J., Lourenço, S., Pires, A. C., Mendonça, P., & Malhado, J. A. (2008). Mycoplasma pneumoniae-associated mucositis with minimal skin manifestations. American Journal of Clinical Dermatology, 9(6), 399-403. https://doi.org/10.2165/0128071-200809060-00008
Figueira-Coelho J, et al. Mycoplasma Pneumoniae-associated Mucositis With Minimal Skin Manifestations. Am J Clin Dermatol. 2008;9(6):399-403. PubMed PMID: 18973408.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mycoplasma pneumoniae-associated mucositis with minimal skin manifestations. AU - Figueira-Coelho,João, AU - Lourenço,Sofia, AU - Pires,Ana Cristina, AU - Mendonça,Paula, AU - Malhado,José António, PY - 2008/11/1/pubmed PY - 2009/2/20/medline PY - 2008/11/1/entrez SP - 399 EP - 403 JF - American journal of clinical dermatology JO - Am J Clin Dermatol VL - 9 IS - 6 N2 - Mycoplasma pneumoniae-associated mucositis is a rarely described complication of M. pneumoniae infection presenting with ocular, oral, and genital involvement but without the typical skin lesions seen in Stevens-Johnson syndrome. A 27-year-old man with a past history of asthma presented at the emergency room with a 1-week history of cough (initially non-productive but subsequently associated with non-bloody mucopurulent sputum), fever, myalgias, headache, and progressive dyspnea. Two days before admission he had commenced amoxicillin/clavulanic acid with no improvement. The patient reported bilateral conjunctival injection and hemorrhagic ulcers on the lips commencing the day prior to admission. Physical examination revealed fever (39 degrees C), bilateral exudative conjunctivitis, painful hemorrhagic ulcers on the lips, tongue, and oral mucosa, small scrotal erosions, erythema of the penile meatus, and small erythematous bullae on the dorsum of each hand; subsequently, the patient developed bullae at the venipuncture site on his right arm. Laboratory tests revealed positive IgM serology for M. pneumoniae, with titer elevation. The patient was successfully treated with levofloxacin and prednisolone. Our case appears to be the first adult patient described with M. pneumoniae-associated mucositis, which has previously been reported only in pediatric patients. This is also the first reported instance of a case of M. pneumoniae-associated mucositis treated with levofloxacin and prednisolone. M. pneumoniae infection should be considered in all cases of mucositis, and treatment of this condition with levofloxacin and prednisolone seems to be effective. SN - 1175-0561 UR - https://www.unboundmedicine.com/medline/citation/18973408/Mycoplasma_pneumoniae_associated_mucositis_with_minimal_skin_manifestations_ L2 - https://dx.doi.org/10.2165/0128071-200809060-00008 DB - PRIME DP - Unbound Medicine ER -