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Additive effect between quinine oxidoreductase gene (NQO1: Pro187Ser) and manganese superoxide dismutase gene (MnSOD: Ala-9Val) polymorphisms on tardive dyskinesia in patients with schizophrenia.
Psychiatry Res. 2008 Dec 15; 161(3):336-8.PR

Abstract

This study investigated whether there was an interaction between the NQO1 Pro187Ser and MnSOD Ala-9Val gene polymorphisms in the development of tardive dyskinesia (TD). The combined genotypes of T/T in NQO1 Pro187Ser and Val/Val in MnSOD Ala-9Val polymorphisms were found to be independently associated with a significantly higher risk of TD. However, further adequately powered studies will be needed to confirm these preliminary findings.

Authors+Show Affiliations

Department of Psychiatry, Kangnam St Mary's Hospital, The Catholic University of Korea, College of Medicine, Seocho-Gu, Seoul, Republic of Korea. pae@catholic.ac.kr

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18977034

Citation

Pae, Chi-Un. "Additive Effect Between Quinine Oxidoreductase Gene (NQO1: Pro187Ser) and Manganese Superoxide Dismutase Gene (MnSOD: Ala-9Val) Polymorphisms On Tardive Dyskinesia in Patients With Schizophrenia." Psychiatry Research, vol. 161, no. 3, 2008, pp. 336-8.
Pae CU. Additive effect between quinine oxidoreductase gene (NQO1: Pro187Ser) and manganese superoxide dismutase gene (MnSOD: Ala-9Val) polymorphisms on tardive dyskinesia in patients with schizophrenia. Psychiatry Res. 2008;161(3):336-8.
Pae, C. U. (2008). Additive effect between quinine oxidoreductase gene (NQO1: Pro187Ser) and manganese superoxide dismutase gene (MnSOD: Ala-9Val) polymorphisms on tardive dyskinesia in patients with schizophrenia. Psychiatry Research, 161(3), 336-8. https://doi.org/10.1016/j.psychres.2006.10.005
Pae CU. Additive Effect Between Quinine Oxidoreductase Gene (NQO1: Pro187Ser) and Manganese Superoxide Dismutase Gene (MnSOD: Ala-9Val) Polymorphisms On Tardive Dyskinesia in Patients With Schizophrenia. Psychiatry Res. 2008 Dec 15;161(3):336-8. PubMed PMID: 18977034.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Additive effect between quinine oxidoreductase gene (NQO1: Pro187Ser) and manganese superoxide dismutase gene (MnSOD: Ala-9Val) polymorphisms on tardive dyskinesia in patients with schizophrenia. A1 - Pae,Chi-Un, Y1 - 2008/10/31/ PY - 2006/04/27/received PY - 2006/08/04/revised PY - 2006/10/02/accepted PY - 2008/11/4/pubmed PY - 2009/2/5/medline PY - 2008/11/4/entrez SP - 336 EP - 8 JF - Psychiatry research JO - Psychiatry Res VL - 161 IS - 3 N2 - This study investigated whether there was an interaction between the NQO1 Pro187Ser and MnSOD Ala-9Val gene polymorphisms in the development of tardive dyskinesia (TD). The combined genotypes of T/T in NQO1 Pro187Ser and Val/Val in MnSOD Ala-9Val polymorphisms were found to be independently associated with a significantly higher risk of TD. However, further adequately powered studies will be needed to confirm these preliminary findings. SN - 0165-1781 UR - https://www.unboundmedicine.com/medline/citation/18977034/Additive_effect_between_quinine_oxidoreductase_gene__NQO1:_Pro187Ser__and_manganese_superoxide_dismutase_gene__MnSOD:_Ala_9Val__polymorphisms_on_tardive_dyskinesia_in_patients_with_schizophrenia_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-1781(06)00319-2 DB - PRIME DP - Unbound Medicine ER -