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Prevention of rickets and vitamin D deficiency in infants, children, and adolescents.
Pediatrics 2008; 122(5):1142-52Ped

Abstract

Rickets in infants attributable to inadequate vitamin D intake and decreased exposure to sunlight continues to be reported in the United States. There are also concerns for vitamin D deficiency in older children and adolescents. Because there are limited natural dietary sources of vitamin D and adequate sunshine exposure for the cutaneous synthesis of vitamin D is not easily determined for a given individual and may increase the risk of skin cancer, the recommendations to ensure adequate vitamin D status have been revised to include all infants, including those who are exclusively breastfed and older children and adolescents. It is now recommended that all infants and children, including adolescents, have a minimum daily intake of 400 IU of vitamin D beginning soon after birth. The current recommendation replaces the previous recommendation of a minimum daily intake of 200 IU/day of vitamin D supplementation beginning in the first 2 months after birth and continuing through adolescence. These revised guidelines for vitamin D intake for healthy infants, children, and adolescents are based on evidence from new clinical trials and the historical precedence of safely giving 400 IU of vitamin D per day in the pediatric and adolescent population. New evidence supports a potential role for vitamin D in maintaining innate immunity and preventing diseases such as diabetes and cancer. The new data may eventually refine what constitutes vitamin D sufficiency or deficiency.

Authors+Show Affiliations

American College of Obstetrics and Gynecology.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18977996

Citation

Wagner, Carol L., et al. "Prevention of Rickets and Vitamin D Deficiency in Infants, Children, and Adolescents." Pediatrics, vol. 122, no. 5, 2008, pp. 1142-52.
Wagner CL, Greer FR, American Academy of Pediatrics Section on Breastfeeding, et al. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics. 2008;122(5):1142-52.
Wagner, C. L., & Greer, F. R. (2008). Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics, 122(5), pp. 1142-52. doi:10.1542/peds.2008-1862.
Wagner CL, et al. Prevention of Rickets and Vitamin D Deficiency in Infants, Children, and Adolescents. Pediatrics. 2008;122(5):1142-52. PubMed PMID: 18977996.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. AU - Wagner,Carol L, AU - Greer,Frank R, AU - ,, AU - ,, PY - 2008/11/4/pubmed PY - 2008/12/17/medline PY - 2008/11/4/entrez SP - 1142 EP - 52 JF - Pediatrics JO - Pediatrics VL - 122 IS - 5 N2 - Rickets in infants attributable to inadequate vitamin D intake and decreased exposure to sunlight continues to be reported in the United States. There are also concerns for vitamin D deficiency in older children and adolescents. Because there are limited natural dietary sources of vitamin D and adequate sunshine exposure for the cutaneous synthesis of vitamin D is not easily determined for a given individual and may increase the risk of skin cancer, the recommendations to ensure adequate vitamin D status have been revised to include all infants, including those who are exclusively breastfed and older children and adolescents. It is now recommended that all infants and children, including adolescents, have a minimum daily intake of 400 IU of vitamin D beginning soon after birth. The current recommendation replaces the previous recommendation of a minimum daily intake of 200 IU/day of vitamin D supplementation beginning in the first 2 months after birth and continuing through adolescence. These revised guidelines for vitamin D intake for healthy infants, children, and adolescents are based on evidence from new clinical trials and the historical precedence of safely giving 400 IU of vitamin D per day in the pediatric and adolescent population. New evidence supports a potential role for vitamin D in maintaining innate immunity and preventing diseases such as diabetes and cancer. The new data may eventually refine what constitutes vitamin D sufficiency or deficiency. SN - 1098-4275 UR - https://www.unboundmedicine.com/medline/citation/18977996/Prevention_of_rickets_and_vitamin_D_deficiency_in_infants_children_and_adolescents_ L2 - http://pediatrics.aappublications.org/cgi/pmidlookup?view=long&pmid=18977996 DB - PRIME DP - Unbound Medicine ER -