Construction of the adamantane core of plukenetione-type polycyclic polyprenylated acylphloroglucinols.
The construction of a highly functionalized adamantane core of plukenetione-type polycyclic polyprenylated acylphloroglucinols (PPAPs) is described. The method features the construction of the bicyclo[3.3.1]nonane core (3) by successive Michael reactions and the construction of the adamantane core of plukenetione-type PPAPs by acid-catalyzed cyclization of a bicyclo[3.3.1]nonane precursor (2).
Department of Chemistry, Graduate School of Science, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Japan. email@example.com,
Magnetic Resonance Spectroscopy
Pub Type(s)Journal Article
Research Support, Non-U.S. Gov't