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Antibiotic use in sexually transmissible diseases.
Dermatol Clin. 2009 Jan; 27(1):49-61.DC

Abstract

Sexually transmissible diseases (STDs) remain a major health issue worldwide, with approximately 300 million new cases annually. STDs caused by bacteria can be treated with antibiotics, although the susceptibility pattern of many etiologic microbes has changed over the past few decades. Syphilis remains best managed with single-dose benzathine penicillin G. Other single-dose antibiotic regimens for lues are either associated with clinical failure or of uncertain dosage. However, single-dose azithromycin and ceftriaxone are suitable for chancroid. Lymphogranuloma venereum, reemergent as a cause of proctitis, is treated with prolonged courses of doxycycline or minocycline. Trimethoprim-sulfamethoxazole has replaced tetracycline derivatives as preferred treatment for donovanosis in many regions. Parenteral cephalosporins, such as ceftriaxone, cefotaxime, and ceftizoxime, are initial interventions for disseminated gonococcemia. Pending culture results, genital bite wounds (often consisting of deep, painful ulcerations) should be treated with high-dose amoxicillin-clavulanic acid.

Authors+Show Affiliations

Department of Dermatology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA. vampireted@aol.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

18984368

Citation

Rosen, Ted, et al. "Antibiotic Use in Sexually Transmissible Diseases." Dermatologic Clinics, vol. 27, no. 1, 2009, pp. 49-61.
Rosen T, Vandergriff T, Harting M. Antibiotic use in sexually transmissible diseases. Dermatol Clin. 2009;27(1):49-61.
Rosen, T., Vandergriff, T., & Harting, M. (2009). Antibiotic use in sexually transmissible diseases. Dermatologic Clinics, 27(1), 49-61. https://doi.org/10.1016/j.det.2008.07.002
Rosen T, Vandergriff T, Harting M. Antibiotic Use in Sexually Transmissible Diseases. Dermatol Clin. 2009;27(1):49-61. PubMed PMID: 18984368.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antibiotic use in sexually transmissible diseases. AU - Rosen,Ted, AU - Vandergriff,Travis, AU - Harting,Mandy, PY - 2008/11/6/pubmed PY - 2009/4/25/medline PY - 2008/11/6/entrez SP - 49 EP - 61 JF - Dermatologic clinics JO - Dermatol Clin VL - 27 IS - 1 N2 - Sexually transmissible diseases (STDs) remain a major health issue worldwide, with approximately 300 million new cases annually. STDs caused by bacteria can be treated with antibiotics, although the susceptibility pattern of many etiologic microbes has changed over the past few decades. Syphilis remains best managed with single-dose benzathine penicillin G. Other single-dose antibiotic regimens for lues are either associated with clinical failure or of uncertain dosage. However, single-dose azithromycin and ceftriaxone are suitable for chancroid. Lymphogranuloma venereum, reemergent as a cause of proctitis, is treated with prolonged courses of doxycycline or minocycline. Trimethoprim-sulfamethoxazole has replaced tetracycline derivatives as preferred treatment for donovanosis in many regions. Parenteral cephalosporins, such as ceftriaxone, cefotaxime, and ceftizoxime, are initial interventions for disseminated gonococcemia. Pending culture results, genital bite wounds (often consisting of deep, painful ulcerations) should be treated with high-dose amoxicillin-clavulanic acid. SN - 1558-0520 UR - https://www.unboundmedicine.com/medline/citation/18984368/Antibiotic_use_in_sexually_transmissible_diseases L2 - https://linkinghub.elsevier.com/retrieve/pii/S0733-8635(08)00066-1 DB - PRIME DP - Unbound Medicine ER -