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[Fungal allergy in chronic rhinosinusitis with or without polyps].
Kulak Burun Bogaz Ihtis Derg. 2008 May-Jun; 18(3):153-6.KB

Abstract

OBJECTIVES

Fungi, by systemic or local allergic effect, may play a role in the pathogenesis of chronic rhinosinusitis (CRS). We investigated the incidence of fungal allergy in patients with CRS and its effect on the clinical characteristics of the disease.

PATIENTS AND METHODS

The study included 127 patients, aged 18 years or over, with CRS (42 females, 85 males; mean age 43+/-12 years; range 19 to 78 years). Fungal allergy was determined by skin prick test and its effect was analyzed on blood eosinophil and total immunoglobulin E levels, the presence of polyps, and paranasal sinus computed tomography scores.

RESULTS

Eighty-five patients (66.9%) were found to have allergy. The incidence of allergy did not differ between patients with and without polyps (p>0.05). House dust mites (62.2%) were the most frequent allergens. The incidence of fungal allergy was 38.8% in allergic patients. Isolated fungal allergy was detected in two patients (1.6%). The most frequent fungal allergens were Aspergillus, followed by Alternaria, and Penicillium. No association was found between fungal allergy and blood eosinophil and total immunoglobulin E levels, presence of polyps, or paranasal sinus computed tomography scores (p>0.05).

CONCLUSION

The incidence of fungal allergy in patients with CRS was found to be high in this study. Tissue culture studies are required to determine the definitive relationship between fungal allergy and clinical features of CRS.

Authors+Show Affiliations

Department of Otolaryngology, Medicine Faculty of Başkent University, Ankara, Turkey. selimerbek@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

tur

PubMed ID

18984996

Citation

Erbek, Selim S., et al. "[Fungal Allergy in Chronic Rhinosinusitis With or Without Polyps]." Kulak Burun Bogaz Ihtisas Dergisi : KBB = Journal of Ear, Nose, and Throat, vol. 18, no. 3, 2008, pp. 153-6.
Erbek SS, Topal O, Erbek S, et al. [Fungal allergy in chronic rhinosinusitis with or without polyps]. Kulak Burun Bogaz Ihtis Derg. 2008;18(3):153-6.
Erbek, S. S., Topal, O., Erbek, S., & Cakmak, O. (2008). [Fungal allergy in chronic rhinosinusitis with or without polyps]. Kulak Burun Bogaz Ihtisas Dergisi : KBB = Journal of Ear, Nose, and Throat, 18(3), 153-6.
Erbek SS, et al. [Fungal Allergy in Chronic Rhinosinusitis With or Without Polyps]. Kulak Burun Bogaz Ihtis Derg. 2008 May-Jun;18(3):153-6. PubMed PMID: 18984996.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Fungal allergy in chronic rhinosinusitis with or without polyps]. AU - Erbek,Selim S, AU - Topal,Ozgül, AU - Erbek,Seyra, AU - Cakmak,Ozcan, PY - 2008/11/6/pubmed PY - 2010/5/12/medline PY - 2008/11/6/entrez SP - 153 EP - 6 JF - Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat JO - Kulak Burun Bogaz Ihtis Derg VL - 18 IS - 3 N2 - OBJECTIVES: Fungi, by systemic or local allergic effect, may play a role in the pathogenesis of chronic rhinosinusitis (CRS). We investigated the incidence of fungal allergy in patients with CRS and its effect on the clinical characteristics of the disease. PATIENTS AND METHODS: The study included 127 patients, aged 18 years or over, with CRS (42 females, 85 males; mean age 43+/-12 years; range 19 to 78 years). Fungal allergy was determined by skin prick test and its effect was analyzed on blood eosinophil and total immunoglobulin E levels, the presence of polyps, and paranasal sinus computed tomography scores. RESULTS: Eighty-five patients (66.9%) were found to have allergy. The incidence of allergy did not differ between patients with and without polyps (p>0.05). House dust mites (62.2%) were the most frequent allergens. The incidence of fungal allergy was 38.8% in allergic patients. Isolated fungal allergy was detected in two patients (1.6%). The most frequent fungal allergens were Aspergillus, followed by Alternaria, and Penicillium. No association was found between fungal allergy and blood eosinophil and total immunoglobulin E levels, presence of polyps, or paranasal sinus computed tomography scores (p>0.05). CONCLUSION: The incidence of fungal allergy in patients with CRS was found to be high in this study. Tissue culture studies are required to determine the definitive relationship between fungal allergy and clinical features of CRS. SN - 1300-7475 UR - https://www.unboundmedicine.com/medline/citation/18984996/[Fungal_allergy_in_chronic_rhinosinusitis_with_or_without_polyps]_ L2 - https://medlineplus.gov/sinusitis.html DB - PRIME DP - Unbound Medicine ER -