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Effect of carbaryl on some biochemical changes in rats: the ameliorative effect of bee pollen.
Food Chem Toxicol 2009; 47(1):86-91FC

Abstract

In this study, 42 female Wistar albino rats, weighing between 200 and 250 g, were used and they were divided into six equal groups. Group 1 was allocated as the control group. Rats included in groups 2 and 3 were administered a water-solubilized extract of bee pollen at a dose of 50 mg/kg bw/day and 100 mg/kg bw/day, respectively. Group 4 received 225 mg/kg bw/day carbaryl. Groups 5 and 6 were given a water-solubilized extract of bee pollen at a dose of 50 mg/kg bw/day and 100mg/kg bw/day, respectively, plus 225 mg/kg bw/day carbaryl. The indicated administrations were continued for 21 days for groups 1-6 by gavage. MDA levels and the activities of CAT, SOD and GSH-Px were analysed in blood and tissues (liver, kidney, brain and heart). At the same time, levels/activities of total protein, albumin, glucose, triglyceride, T-cholesterol, T-bilirubin, BUN, creatinine, uric acid, GGT, LDH, AST, ALT and ALP, magnesium, sodium, potassium and chloride were evaluated in serum samples. In conclusion, carbaryl was determined to cause negative changes in most of the oxidative stress markers and serum biochemical parameters investigated. These effects were observed to alleviate with the administration of bee pollen.

Authors+Show Affiliations

University of Erciyes, Faculty of Veterinary Medicine, Department of Pharmacology and Toxicology, 38090, Kocasinan, Kayseri, Turkey. geraslan38@hotmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18996165

Citation

Eraslan, Gökhan, et al. "Effect of Carbaryl On some Biochemical Changes in Rats: the Ameliorative Effect of Bee Pollen." Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association, vol. 47, no. 1, 2009, pp. 86-91.
Eraslan G, Kanbur M, Silici S. Effect of carbaryl on some biochemical changes in rats: the ameliorative effect of bee pollen. Food Chem Toxicol. 2009;47(1):86-91.
Eraslan, G., Kanbur, M., & Silici, S. (2009). Effect of carbaryl on some biochemical changes in rats: the ameliorative effect of bee pollen. Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association, 47(1), pp. 86-91. doi:10.1016/j.fct.2008.10.013.
Eraslan G, Kanbur M, Silici S. Effect of Carbaryl On some Biochemical Changes in Rats: the Ameliorative Effect of Bee Pollen. Food Chem Toxicol. 2009;47(1):86-91. PubMed PMID: 18996165.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of carbaryl on some biochemical changes in rats: the ameliorative effect of bee pollen. AU - Eraslan,Gökhan, AU - Kanbur,Murat, AU - Silici,Sibel, Y1 - 2008/10/21/ PY - 2008/01/18/received PY - 2008/10/04/revised PY - 2008/10/13/accepted PY - 2008/11/11/pubmed PY - 2009/3/17/medline PY - 2008/11/11/entrez SP - 86 EP - 91 JF - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association JO - Food Chem. Toxicol. VL - 47 IS - 1 N2 - In this study, 42 female Wistar albino rats, weighing between 200 and 250 g, were used and they were divided into six equal groups. Group 1 was allocated as the control group. Rats included in groups 2 and 3 were administered a water-solubilized extract of bee pollen at a dose of 50 mg/kg bw/day and 100 mg/kg bw/day, respectively. Group 4 received 225 mg/kg bw/day carbaryl. Groups 5 and 6 were given a water-solubilized extract of bee pollen at a dose of 50 mg/kg bw/day and 100mg/kg bw/day, respectively, plus 225 mg/kg bw/day carbaryl. The indicated administrations were continued for 21 days for groups 1-6 by gavage. MDA levels and the activities of CAT, SOD and GSH-Px were analysed in blood and tissues (liver, kidney, brain and heart). At the same time, levels/activities of total protein, albumin, glucose, triglyceride, T-cholesterol, T-bilirubin, BUN, creatinine, uric acid, GGT, LDH, AST, ALT and ALP, magnesium, sodium, potassium and chloride were evaluated in serum samples. In conclusion, carbaryl was determined to cause negative changes in most of the oxidative stress markers and serum biochemical parameters investigated. These effects were observed to alleviate with the administration of bee pollen. SN - 1873-6351 UR - http://www.unboundmedicine.com/medline/citation/18996165/Effect_of_carbaryl_on_some_biochemical_changes_in_rats:_the_ameliorative_effect_of_bee_pollen_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0278-6915(08)00595-4 DB - PRIME DP - Unbound Medicine ER -