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Adverse drug reactions in patients with cardiovascular disease.
Curr Probl Cardiol 2008; 33(12):703-68CP

Abstract

Adverse drug reactions (ADRs) occur frequently in modern medical practice, increasing morbidity and mortality and inflating the cost of care. Patients with cardiovascular disease are particularly vulnerable to ADRs due to their advanced age, polypharmacy, and the influence of heart disease on drug metabolism. The ADR potential for a particular cardiovascular drug varies with the individual, the disease being treated, and the extent of exposure to other drugs. Knowledge of this complex interplay between patient, drug, and disease is a critical component of safe and effective cardiovascular disease management. The majority of significant ADRs involving cardiovascular drugs are predictable and therefore preventable. Better patient education, avoidance of polypharmacy, and clear communication between physicians, pharmacists, and patients, particularly during the transition between the inpatient to outpatient settings, can substantially reduce ADR risk.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19000586

Citation

Faulx, Michael D., and Gary S. Francis. "Adverse Drug Reactions in Patients With Cardiovascular Disease." Current Problems in Cardiology, vol. 33, no. 12, 2008, pp. 703-68.
Faulx MD, Francis GS. Adverse drug reactions in patients with cardiovascular disease. Curr Probl Cardiol. 2008;33(12):703-68.
Faulx, M. D., & Francis, G. S. (2008). Adverse drug reactions in patients with cardiovascular disease. Current Problems in Cardiology, 33(12), pp. 703-68. doi:10.1016/j.cpcardiol.2008.08.002.
Faulx MD, Francis GS. Adverse Drug Reactions in Patients With Cardiovascular Disease. Curr Probl Cardiol. 2008;33(12):703-68. PubMed PMID: 19000586.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adverse drug reactions in patients with cardiovascular disease. AU - Faulx,Michael D, AU - Francis,Gary S, Y1 - 2008/09/27/ PY - 2008/11/13/pubmed PY - 2009/1/23/medline PY - 2008/11/13/entrez SP - 703 EP - 68 JF - Current problems in cardiology JO - Curr Probl Cardiol VL - 33 IS - 12 N2 - Adverse drug reactions (ADRs) occur frequently in modern medical practice, increasing morbidity and mortality and inflating the cost of care. Patients with cardiovascular disease are particularly vulnerable to ADRs due to their advanced age, polypharmacy, and the influence of heart disease on drug metabolism. The ADR potential for a particular cardiovascular drug varies with the individual, the disease being treated, and the extent of exposure to other drugs. Knowledge of this complex interplay between patient, drug, and disease is a critical component of safe and effective cardiovascular disease management. The majority of significant ADRs involving cardiovascular drugs are predictable and therefore preventable. Better patient education, avoidance of polypharmacy, and clear communication between physicians, pharmacists, and patients, particularly during the transition between the inpatient to outpatient settings, can substantially reduce ADR risk. SN - 1535-6280 UR - https://www.unboundmedicine.com/medline/citation/19000586/Adverse_drug_reactions_in_patients_with_cardiovascular_disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0146-2806(08)00125-4 DB - PRIME DP - Unbound Medicine ER -