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Long-term predictors of increased mortality risk in screened men with new hypertension; the Malmo preventive project.
J Hypertens 2008; 26(12):2288-94JH

Abstract

OBJECTIVE

Regular blood pressure control has been advocated for early detection and treatment of patients with hypertension. We aimed to study whether long-term survival rate is related to socioeconomic circumstances and biological factors among middle-aged men with screened new hypertension.

METHODS

Of the 22,444 men who attended a general health examination in Malmo, Sweden during 1974--1984, in total, 2033 had a systolic or diastolic blood pressure of at least 160 or 100 mmHg and were without treatment for hypertension. Mean age was 45.8 (SD: 5.3) years. All-cause mortality was studied in relation to smoking, diabetes, hyperlipidaemia, being overweight, marital status, problematic alcohol drinking, and occupation over a mean follow-up of 18.6 (3.6) years.

RESULTS

Screened hypertension (> or = 160/ > or = 100 mmHg) was significantly more common among men with low occupational level and among single men. Higher risk factor levels were associated with an adverse social background. Of the men with screened hypertension, 479 (24%) died during the follow-up, half of them from cardiovascular diseases. Compared with married men with normal blood pressure, married men with screened hypertension had a relative mortality risk of 1.5 (95% confidence interval = 1.3-1.7), whereas the relative risk for corresponding single men was 3.0 (2.6-3.4) adjusted for confounders. Among men with screened hypertension, marital status, systolic blood pressure at baseline, smoking, diabetes, hyperlipidaemia, and low occupation level (manual) remained significantly associated with total mortality in the multivariate analysis.

CONCLUSION

Marital status contributes substantially to the survival prognosis for men with screened new hypertension. Systolic blood pressure at baseline and other known risk factors for atherosclerosis were also associated with increased mortality in this group.

Authors+Show Affiliations

Department of Clinical Sciences, Cardiovascular Group, Malmö University Hospital, Lund University, Malmo, Sweden. Peter.Nilsson@med.lu.seNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19008707

Citation

Nilsson, Peter M., et al. "Long-term Predictors of Increased Mortality Risk in Screened Men With New Hypertension; the Malmo Preventive Project." Journal of Hypertension, vol. 26, no. 12, 2008, pp. 2288-94.
Nilsson PM, Engström G, Hedblad B. Long-term predictors of increased mortality risk in screened men with new hypertension; the Malmo preventive project. J Hypertens. 2008;26(12):2288-94.
Nilsson, P. M., Engström, G., & Hedblad, B. (2008). Long-term predictors of increased mortality risk in screened men with new hypertension; the Malmo preventive project. Journal of Hypertension, 26(12), pp. 2288-94. doi:10.1097/HJH.0b013e32831313b1.
Nilsson PM, Engström G, Hedblad B. Long-term Predictors of Increased Mortality Risk in Screened Men With New Hypertension; the Malmo Preventive Project. J Hypertens. 2008;26(12):2288-94. PubMed PMID: 19008707.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term predictors of increased mortality risk in screened men with new hypertension; the Malmo preventive project. AU - Nilsson,Peter M, AU - Engström,Gunnar, AU - Hedblad,Bo, PY - 2008/11/15/pubmed PY - 2009/2/14/medline PY - 2008/11/15/entrez SP - 2288 EP - 94 JF - Journal of hypertension JO - J. Hypertens. VL - 26 IS - 12 N2 - OBJECTIVE: Regular blood pressure control has been advocated for early detection and treatment of patients with hypertension. We aimed to study whether long-term survival rate is related to socioeconomic circumstances and biological factors among middle-aged men with screened new hypertension. METHODS: Of the 22,444 men who attended a general health examination in Malmo, Sweden during 1974--1984, in total, 2033 had a systolic or diastolic blood pressure of at least 160 or 100 mmHg and were without treatment for hypertension. Mean age was 45.8 (SD: 5.3) years. All-cause mortality was studied in relation to smoking, diabetes, hyperlipidaemia, being overweight, marital status, problematic alcohol drinking, and occupation over a mean follow-up of 18.6 (3.6) years. RESULTS: Screened hypertension (> or = 160/ > or = 100 mmHg) was significantly more common among men with low occupational level and among single men. Higher risk factor levels were associated with an adverse social background. Of the men with screened hypertension, 479 (24%) died during the follow-up, half of them from cardiovascular diseases. Compared with married men with normal blood pressure, married men with screened hypertension had a relative mortality risk of 1.5 (95% confidence interval = 1.3-1.7), whereas the relative risk for corresponding single men was 3.0 (2.6-3.4) adjusted for confounders. Among men with screened hypertension, marital status, systolic blood pressure at baseline, smoking, diabetes, hyperlipidaemia, and low occupation level (manual) remained significantly associated with total mortality in the multivariate analysis. CONCLUSION: Marital status contributes substantially to the survival prognosis for men with screened new hypertension. Systolic blood pressure at baseline and other known risk factors for atherosclerosis were also associated with increased mortality in this group. SN - 0263-6352 UR - https://www.unboundmedicine.com/medline/citation/19008707/Long_term_predictors_of_increased_mortality_risk_in_screened_men_with_new_hypertension L2 - http://Insights.ovid.com/pubmed?pmid=19008707 DB - PRIME DP - Unbound Medicine ER -