Tags

Type your tag names separated by a space and hit enter

Bone stiffness in men with type 2 diabetes mellitus.
Metabolism. 2008 Dec; 57(12):1691-5.M

Abstract

Osteoporosis in elderly men as well as women is increasingly recognized, and patients with type 2 diabetes mellitus have higher risk of fracture than nondiabetic subjects. The aim of the present study was to investigate the relationship between bone stiffness and serum testosterone concentration as well as other variables in men with type 2 diabetes mellitus. The relationships between bone stiffness and serum bioavailable testosterone concentrations as well as other variables including age, duration of diabetes, glycemic control (hemoglobin A(1c)), or body mass index were evaluated in 294 men with type 2 diabetes mellitus. An inverse correlation was found between stiffness index and age. A positive correlation was found between stiffness index and serum bioavailable testosterone concentration (r = 0.231, P = .0005). Stiffness index was significantly less in current smokers (81.6 +/- 17.7) than in past smokers (86.6 +/- 17.8, P = .0396) or nonsmokers (87.7 +/- 15.2, P = .0426). Multiple regression analysis demonstrated that serum bioavailable testosterone concentration (beta = .271, P = .0006) and smoking status (beta = -0.147, P = .0408) were independent determinants of stiffness index. In conclusion, bone stiffness was associated with serum bioavailable testosterone concentration but not associated with hemoglobin A(1c) or duration of diabetes in men with type 2 diabetes mellitus.

Authors+Show Affiliations

Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19013292

Citation

Asano, Mai, et al. "Bone Stiffness in Men With Type 2 Diabetes Mellitus." Metabolism: Clinical and Experimental, vol. 57, no. 12, 2008, pp. 1691-5.
Asano M, Fukui M, Hosoda H, et al. Bone stiffness in men with type 2 diabetes mellitus. Metab Clin Exp. 2008;57(12):1691-5.
Asano, M., Fukui, M., Hosoda, H., Shiraishi, E., Harusato, I., Kadono, M., Tanaka, M., Hasegawa, G., Yoshikawa, T., & Nakamura, N. (2008). Bone stiffness in men with type 2 diabetes mellitus. Metabolism: Clinical and Experimental, 57(12), 1691-5. https://doi.org/10.1016/j.metabol.2008.07.025
Asano M, et al. Bone Stiffness in Men With Type 2 Diabetes Mellitus. Metab Clin Exp. 2008;57(12):1691-5. PubMed PMID: 19013292.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bone stiffness in men with type 2 diabetes mellitus. AU - Asano,Mai, AU - Fukui,Michiaki, AU - Hosoda,Hiroko, AU - Shiraishi,Emi, AU - Harusato,Ichiko, AU - Kadono,Mayuko, AU - Tanaka,Muhei, AU - Hasegawa,Goji, AU - Yoshikawa,Toshikazu, AU - Nakamura,Naoto, PY - 2008/05/20/received PY - 2008/07/29/accepted PY - 2008/11/18/pubmed PY - 2008/12/17/medline PY - 2008/11/18/entrez SP - 1691 EP - 5 JF - Metabolism: clinical and experimental JO - Metab. Clin. Exp. VL - 57 IS - 12 N2 - Osteoporosis in elderly men as well as women is increasingly recognized, and patients with type 2 diabetes mellitus have higher risk of fracture than nondiabetic subjects. The aim of the present study was to investigate the relationship between bone stiffness and serum testosterone concentration as well as other variables in men with type 2 diabetes mellitus. The relationships between bone stiffness and serum bioavailable testosterone concentrations as well as other variables including age, duration of diabetes, glycemic control (hemoglobin A(1c)), or body mass index were evaluated in 294 men with type 2 diabetes mellitus. An inverse correlation was found between stiffness index and age. A positive correlation was found between stiffness index and serum bioavailable testosterone concentration (r = 0.231, P = .0005). Stiffness index was significantly less in current smokers (81.6 +/- 17.7) than in past smokers (86.6 +/- 17.8, P = .0396) or nonsmokers (87.7 +/- 15.2, P = .0426). Multiple regression analysis demonstrated that serum bioavailable testosterone concentration (beta = .271, P = .0006) and smoking status (beta = -0.147, P = .0408) were independent determinants of stiffness index. In conclusion, bone stiffness was associated with serum bioavailable testosterone concentration but not associated with hemoglobin A(1c) or duration of diabetes in men with type 2 diabetes mellitus. SN - 1532-8600 UR - https://www.unboundmedicine.com/medline/citation/19013292/Bone_stiffness_in_men_with_type_2_diabetes_mellitus_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0026-0495(08)00282-5 DB - PRIME DP - Unbound Medicine ER -