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Insulin strategies for managing inpatient and outpatient hyperglycemia and diabetes.
Mt Sinai J Med. 2008 Dec 01; 75(6):558-66.MS

Abstract

Optimal fasting and postprandial glycemic control are essential to limiting microvascular and macrovascular complications associated with diabetes. Recently, stringent control of hyperglycemia in critically ill hospitalized patients with diabetes or acute hyperglycemia has been shown to reduce the risk of morbidity and mortality. This article reviews effective strategies for insulin initiation, titration, and intensification in inpatient and outpatient settings and discusses current treatment strategies when patients are being transitioned from the intensive care unit to general wards and discharged. The development of insulin analogs and premixed insulin analogs has created new options for treating inpatients and outpatients. The more physiologic time-action profiles, improved insulin delivery systems, and standardized protocols for subcutaneous insulin administration and intravenous insulin infusion have improved the safety and convenience of insulin therapy.

Authors+Show Affiliations

Department of Medicine, University of California at Los Angeles, Los Angeles, CA 90292, USA. emoghissi@pol.net

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

19021195

Citation

Moghissi, Etie S.. "Insulin Strategies for Managing Inpatient and Outpatient Hyperglycemia and Diabetes." The Mount Sinai Journal of Medicine, New York, vol. 75, no. 6, 2008, pp. 558-66.
Moghissi ES. Insulin strategies for managing inpatient and outpatient hyperglycemia and diabetes. Mt Sinai J Med. 2008;75(6):558-66.
Moghissi, E. S. (2008). Insulin strategies for managing inpatient and outpatient hyperglycemia and diabetes. The Mount Sinai Journal of Medicine, New York, 75(6), 558-66. https://doi.org/10.1002/msj.20071
Moghissi ES. Insulin Strategies for Managing Inpatient and Outpatient Hyperglycemia and Diabetes. Mt Sinai J Med. 2008 Dec 1;75(6):558-66. PubMed PMID: 19021195.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Insulin strategies for managing inpatient and outpatient hyperglycemia and diabetes. A1 - Moghissi,Etie S, PY - 2008/11/21/pubmed PY - 2009/7/16/medline PY - 2008/11/21/entrez SP - 558 EP - 66 JF - The Mount Sinai journal of medicine, New York JO - Mt Sinai J Med VL - 75 IS - 6 N2 - Optimal fasting and postprandial glycemic control are essential to limiting microvascular and macrovascular complications associated with diabetes. Recently, stringent control of hyperglycemia in critically ill hospitalized patients with diabetes or acute hyperglycemia has been shown to reduce the risk of morbidity and mortality. This article reviews effective strategies for insulin initiation, titration, and intensification in inpatient and outpatient settings and discusses current treatment strategies when patients are being transitioned from the intensive care unit to general wards and discharged. The development of insulin analogs and premixed insulin analogs has created new options for treating inpatients and outpatients. The more physiologic time-action profiles, improved insulin delivery systems, and standardized protocols for subcutaneous insulin administration and intravenous insulin infusion have improved the safety and convenience of insulin therapy. SN - 1931-7581 UR - https://www.unboundmedicine.com/medline/citation/19021195/Insulin_strategies_for_managing_inpatient_and_outpatient_hyperglycemia_and_diabetes_ L2 - https://doi.org/10.1002/msj.20071 DB - PRIME DP - Unbound Medicine ER -