Interlaboratory discrepancy of antigenuria results in 2 patients with AIDS and histoplasmosis.Diagn Microbiol Infect Dis. 2009 Jan; 63(1):111-4.DM
Histoplasma polysaccharide antigen testing is used routinely to diagnose histoplasmosis. At least 3 antigen tests are commercially available. Controversy exists about the relative accuracy of these tests. We report 2 patients with AIDS and culture-confirmed Histoplasma capsulatum meningitis from whom discrepant Histoplasma polysaccharide antigen results were obtained from different laboratories and discuss the potential clinical implications of these results.