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[The prevalence of atrophic gastritis and intestinal metaplasia according to gender, age and Helicobacter pylori infection in a rural population].
J Prev Med Public Health. 2008 Nov; 41(6):373-9.JP

Abstract

OBJECTIVES

The objective of this study was to evaluate the prevalence of atrophic gastritis and intestinal metaplasia according to gender, age and Helicobacter pylori infection in a rural population in Korea.

METHODS

Between April 2003 and January 2007, 713 subjects (298 men and 415 women, age range: 18-85) among the 2,161 adults who participated in a population-based survey received gastrointestinal endoscopy. All the subjects provided informed consent. Multiple biopsy specimens were evaluated for the presence of atrophic gastritis and intestinal metaplasia. The presence of Helicobacter pylori was determined using CLO and histology testing.

RESULTS

The age-adjusted prevalence of atrophic gastritis was 42.7% for men and 38.1% for women and the prevalence of intestinal metaplasia was 42.5% for men and 32.7% for women. The prevalence of atrophic gastritis and intestinal metaplasia increased significantly with age for both men and women (p for trend<0.001). The age-adjusted prevalence of Helicobacter pylori was similar for men (59.0%) and women (56.7%). The subjects with Helicobacter pylori infection showed a significantly higher prevalence of intestinal metaplasia (44.3%) compared with that (26.8%) of the noninfected subjects (p<0.001). However, the prevalence of atrophic gastritis was not statistically different between the Helicobacter pylori-infected subjects and the noninfected individuals.

CONCLUSIONS

Our findings suggest that the prevalence of atrophic gastritis and intestinal metaplasia is higher for a Korean rural population than that for a Western population; this may be related to the high incidence of gastric cancer in Koreans. Especially, the prevalence of intestinal metaplasia was high for the subjects with Helicobacter pylori infection. The multistep process of gastric carcinogenesis and the various factors contributing to each step of this process need to be determined by conducting future follow-up studies.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Kim HJ
Department of Preventive Medicine, Hanyang University College of Medicine.
Choi BY
No affiliation info available
Byun TJ
No affiliation info available
Eun CS
No affiliation info available
Song KS
No affiliation info available
Kim YS
No affiliation info available
Han DS
No affiliation info available

MeSH

AdolescentAdultAge FactorsAgedAged, 80 and overChi-Square DistributionDemographyFemaleGastritis, AtrophicHelicobacter InfectionsHelicobacter pyloriHumansIntestine, SmallMaleMetaplasiaMiddle AgedRural PopulationSex FactorsSocioeconomic Factors

Pub Type(s)

Journal Article

Language

kor

PubMed ID

19037166

Citation

Kim, Hyun Ja, et al. "[The Prevalence of Atrophic Gastritis and Intestinal Metaplasia According to Gender, Age and Helicobacter Pylori Infection in a Rural Population]." Journal of Preventive Medicine and Public Health = Yebang Uihakhoe Chi, vol. 41, no. 6, 2008, pp. 373-9.
Kim HJ, Choi BY, Byun TJ, et al. [The prevalence of atrophic gastritis and intestinal metaplasia according to gender, age and Helicobacter pylori infection in a rural population]. J Prev Med Public Health. 2008;41(6):373-9.
Kim, H. J., Choi, B. Y., Byun, T. J., Eun, C. S., Song, K. S., Kim, Y. S., & Han, D. S. (2008). [The prevalence of atrophic gastritis and intestinal metaplasia according to gender, age and Helicobacter pylori infection in a rural population]. Journal of Preventive Medicine and Public Health = Yebang Uihakhoe Chi, 41(6), 373-9. https://doi.org/10.3961/jpmph.2008.41.6.373
Kim HJ, et al. [The Prevalence of Atrophic Gastritis and Intestinal Metaplasia According to Gender, Age and Helicobacter Pylori Infection in a Rural Population]. J Prev Med Public Health. 2008;41(6):373-9. PubMed PMID: 19037166.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The prevalence of atrophic gastritis and intestinal metaplasia according to gender, age and Helicobacter pylori infection in a rural population]. AU - Kim,Hyun Ja, AU - Choi,Bo Youl, AU - Byun,Tae Joon, AU - Eun,Chang Soo, AU - Song,Kyu Sang, AU - Kim,Yong Sung, AU - Han,Dong Soo, PY - 2008/11/28/pubmed PY - 2009/1/30/medline PY - 2008/11/28/entrez SP - 373 EP - 9 JF - Journal of preventive medicine and public health = Yebang Uihakhoe chi JO - J Prev Med Public Health VL - 41 IS - 6 N2 - OBJECTIVES: The objective of this study was to evaluate the prevalence of atrophic gastritis and intestinal metaplasia according to gender, age and Helicobacter pylori infection in a rural population in Korea. METHODS: Between April 2003 and January 2007, 713 subjects (298 men and 415 women, age range: 18-85) among the 2,161 adults who participated in a population-based survey received gastrointestinal endoscopy. All the subjects provided informed consent. Multiple biopsy specimens were evaluated for the presence of atrophic gastritis and intestinal metaplasia. The presence of Helicobacter pylori was determined using CLO and histology testing. RESULTS: The age-adjusted prevalence of atrophic gastritis was 42.7% for men and 38.1% for women and the prevalence of intestinal metaplasia was 42.5% for men and 32.7% for women. The prevalence of atrophic gastritis and intestinal metaplasia increased significantly with age for both men and women (p for trend<0.001). The age-adjusted prevalence of Helicobacter pylori was similar for men (59.0%) and women (56.7%). The subjects with Helicobacter pylori infection showed a significantly higher prevalence of intestinal metaplasia (44.3%) compared with that (26.8%) of the noninfected subjects (p<0.001). However, the prevalence of atrophic gastritis was not statistically different between the Helicobacter pylori-infected subjects and the noninfected individuals. CONCLUSIONS: Our findings suggest that the prevalence of atrophic gastritis and intestinal metaplasia is higher for a Korean rural population than that for a Western population; this may be related to the high incidence of gastric cancer in Koreans. Especially, the prevalence of intestinal metaplasia was high for the subjects with Helicobacter pylori infection. The multistep process of gastric carcinogenesis and the various factors contributing to each step of this process need to be determined by conducting future follow-up studies. SN - 1975-8375 UR - https://www.unboundmedicine.com/medline/citation/19037166/[The_prevalence_of_atrophic_gastritis_and_intestinal_metaplasia_according_to_gender_age_and_Helicobacter_pylori_infection_in_a_rural_population]_ DB - PRIME DP - Unbound Medicine ER -