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Hepatitis B virus screening for internationally adopted children.
Pediatrics. 2008 Dec; 122(6):1223-8.Ped

Abstract

OBJECTIVES

The objectives of this study were to estimate the prevalence of hepatitis B virus protection, infection, and recovery among internationally adopted children and to examine the need for repeat testing 6 months after arrival in the United States.

METHODS

From November 1999 through October 2006, 1282 international adoptees were screened for hepatitis B virus, and results were examined with regard to age, gender, and birth country. The prevalence of hepatitis B virus protection, infection, and recovery was determined.

RESULTS

The prevalence of hepatitis B virus in internationally adopted children at our large international adoption center was 4%, including 1.1% with acute or chronic infection and 2.9% with resolved infection. Overall, 64% of internationally adopted children had evidence of hepatitis B virus immunization, with protective antibodies. We also report a case that highlights the need for repeat serological testing to detect hepatitis B virus infection or immunization in internationally adopted children who might have been infected or vaccinated just before adoption and thus not have serological evidence in initial testing.

CONCLUSIONS

These data reinforce the American Academy of Pediatrics recommendations regarding hepatitis B virus screening and infection control measures for international adoptees.

Authors+Show Affiliations

Department of Pediatrics, International Adoption Center, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 7013, Cincinnati, OH 45229-3109, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

19047238

Citation

Stadler, Laura Patricia, et al. "Hepatitis B Virus Screening for Internationally Adopted Children." Pediatrics, vol. 122, no. 6, 2008, pp. 1223-8.
Stadler LP, Mezoff AG, Staat MA. Hepatitis B virus screening for internationally adopted children. Pediatrics. 2008;122(6):1223-8.
Stadler, L. P., Mezoff, A. G., & Staat, M. A. (2008). Hepatitis B virus screening for internationally adopted children. Pediatrics, 122(6), 1223-8. https://doi.org/10.1542/peds.2007-2559
Stadler LP, Mezoff AG, Staat MA. Hepatitis B Virus Screening for Internationally Adopted Children. Pediatrics. 2008;122(6):1223-8. PubMed PMID: 19047238.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hepatitis B virus screening for internationally adopted children. AU - Stadler,Laura Patricia, AU - Mezoff,Adam G, AU - Staat,Mary Allen, PY - 2008/12/3/pubmed PY - 2009/1/16/medline PY - 2008/12/3/entrez SP - 1223 EP - 8 JF - Pediatrics JO - Pediatrics VL - 122 IS - 6 N2 - OBJECTIVES: The objectives of this study were to estimate the prevalence of hepatitis B virus protection, infection, and recovery among internationally adopted children and to examine the need for repeat testing 6 months after arrival in the United States. METHODS: From November 1999 through October 2006, 1282 international adoptees were screened for hepatitis B virus, and results were examined with regard to age, gender, and birth country. The prevalence of hepatitis B virus protection, infection, and recovery was determined. RESULTS: The prevalence of hepatitis B virus in internationally adopted children at our large international adoption center was 4%, including 1.1% with acute or chronic infection and 2.9% with resolved infection. Overall, 64% of internationally adopted children had evidence of hepatitis B virus immunization, with protective antibodies. We also report a case that highlights the need for repeat serological testing to detect hepatitis B virus infection or immunization in internationally adopted children who might have been infected or vaccinated just before adoption and thus not have serological evidence in initial testing. CONCLUSIONS: These data reinforce the American Academy of Pediatrics recommendations regarding hepatitis B virus screening and infection control measures for international adoptees. SN - 1098-4275 UR - https://www.unboundmedicine.com/medline/citation/19047238/Hepatitis_B_virus_screening_for_internationally_adopted_children_ L2 - http://pediatrics.aappublications.org/cgi/pmidlookup?view=long&pmid=19047238 DB - PRIME DP - Unbound Medicine ER -