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Binge eating and weight loss outcomes in overweight and obese individuals with type 2 diabetes: results from the Look AHEAD trial.
Arch Gen Psychiatry 2008; 65(12):1447-55AG

Abstract

CONTEXT

Binge eating (BE) is common in overweight and obese individuals with type 2 diabetes mellitus, but little is known about how BE affects weight loss in this population.

OBJECTIVE

To determine whether BE was related to 1-year weight losses in overweight and obese individuals with type 2 diabetes participating in an ongoing clinical trial.

DESIGN, SETTING, AND PARTICIPANTS

The Look AHEAD (Action for Health in Diabetes) trial is a randomized controlled trial examining the long-term effect of intentional weight loss on cardiovascular disease in overweight and obese adults with type 2 diabetes. A total of 5145 overweight and obese individuals aged 45 to 76 years with type 2 diabetes participated in this study.

INTERVENTIONS

Participants were randomly assigned to an intensive lifestyle intervention or to enhanced usual care (a diabetes support and education control condition).

MAIN OUTCOME MEASURES

At baseline and 1 year, participants had their weight measured and completed a fitness test and self-report measures of BE and dietary intake. Four groups were created based on BE status at baseline and 1 year (yes/yes, no/no, yes/no, and no/yes). Analyses controlled for baseline differences between binge eaters and non-binge eaters.

RESULTS

Most individuals (85.4%) did not report BE at baseline or 1 year (no/no), 7.5% reported BE only at baseline (yes/no), 3.7% reported BE at both times (yes/yes), and 3.4% reported BE only at 1 year (no/yes), with no differences between intensive lifestyle intervention and diabetes support and education conditions (P = .14). Across intensive lifestyle intervention and diabetes support and education, greater weight losses were observed in participants who stopped BE at 1 year (mean [SE] weight loss, 5.3 [0.4] kg) and those who reported no BE at either time (mean [SE] weight loss, 4.8 [0.1] kg) than in those who continued BE (mean [SE] weight loss, 3.1 [0.6] kg) and those who began BE at 1 year (mean [SE] weight loss, 3.0 [0.6] kg) (P < .001). Post hoc analyses suggested that these differences were due to changes in caloric intake.

CONCLUSION

Overweight and obese individuals with type 2 diabetes who stop BE appear to be just as successful at weight loss as non-binge eaters after 1 year of treatment.

TRIAL REGISTRATION

clinicaltrials.gov Identifier: NCT00017953.

Authors+Show Affiliations

Department of Psychology, Center for Health, Intervention, and Prevention, University of Connecticut, 2006 Hillside Rd, Unit 1248, Storrs, CT 06269-1248, USA. amy.gorin@uconn.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, N.I.H., Extramural
Research Support, N.I.H., Intramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

19047532

Citation

Gorin, Amy A., et al. "Binge Eating and Weight Loss Outcomes in Overweight and Obese Individuals With Type 2 Diabetes: Results From the Look AHEAD Trial." Archives of General Psychiatry, vol. 65, no. 12, 2008, pp. 1447-55.
Gorin AA, Niemeier HM, Hogan P, et al. Binge eating and weight loss outcomes in overweight and obese individuals with type 2 diabetes: results from the Look AHEAD trial. Arch Gen Psychiatry. 2008;65(12):1447-55.
Gorin, A. A., Niemeier, H. M., Hogan, P., Coday, M., Davis, C., DiLillo, V. G., ... Yanovski, S. Z. (2008). Binge eating and weight loss outcomes in overweight and obese individuals with type 2 diabetes: results from the Look AHEAD trial. Archives of General Psychiatry, 65(12), pp. 1447-55. doi:10.1001/archpsyc.65.12.1447.
Gorin AA, et al. Binge Eating and Weight Loss Outcomes in Overweight and Obese Individuals With Type 2 Diabetes: Results From the Look AHEAD Trial. Arch Gen Psychiatry. 2008;65(12):1447-55. PubMed PMID: 19047532.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Binge eating and weight loss outcomes in overweight and obese individuals with type 2 diabetes: results from the Look AHEAD trial. AU - Gorin,Amy A, AU - Niemeier,Heather M, AU - Hogan,Patricia, AU - Coday,Mace, AU - Davis,Cralen, AU - DiLillo,Vicki G, AU - Gluck,Marci E, AU - Wadden,Thomas A, AU - West,Delia S, AU - Williamson,Donald, AU - Yanovski,Susan Z, AU - ,, PY - 2008/12/3/pubmed PY - 2008/12/25/medline PY - 2008/12/3/entrez SP - 1447 EP - 55 JF - Archives of general psychiatry JO - Arch. Gen. Psychiatry VL - 65 IS - 12 N2 - CONTEXT: Binge eating (BE) is common in overweight and obese individuals with type 2 diabetes mellitus, but little is known about how BE affects weight loss in this population. OBJECTIVE: To determine whether BE was related to 1-year weight losses in overweight and obese individuals with type 2 diabetes participating in an ongoing clinical trial. DESIGN, SETTING, AND PARTICIPANTS: The Look AHEAD (Action for Health in Diabetes) trial is a randomized controlled trial examining the long-term effect of intentional weight loss on cardiovascular disease in overweight and obese adults with type 2 diabetes. A total of 5145 overweight and obese individuals aged 45 to 76 years with type 2 diabetes participated in this study. INTERVENTIONS: Participants were randomly assigned to an intensive lifestyle intervention or to enhanced usual care (a diabetes support and education control condition). MAIN OUTCOME MEASURES: At baseline and 1 year, participants had their weight measured and completed a fitness test and self-report measures of BE and dietary intake. Four groups were created based on BE status at baseline and 1 year (yes/yes, no/no, yes/no, and no/yes). Analyses controlled for baseline differences between binge eaters and non-binge eaters. RESULTS: Most individuals (85.4%) did not report BE at baseline or 1 year (no/no), 7.5% reported BE only at baseline (yes/no), 3.7% reported BE at both times (yes/yes), and 3.4% reported BE only at 1 year (no/yes), with no differences between intensive lifestyle intervention and diabetes support and education conditions (P = .14). Across intensive lifestyle intervention and diabetes support and education, greater weight losses were observed in participants who stopped BE at 1 year (mean [SE] weight loss, 5.3 [0.4] kg) and those who reported no BE at either time (mean [SE] weight loss, 4.8 [0.1] kg) than in those who continued BE (mean [SE] weight loss, 3.1 [0.6] kg) and those who began BE at 1 year (mean [SE] weight loss, 3.0 [0.6] kg) (P < .001). Post hoc analyses suggested that these differences were due to changes in caloric intake. CONCLUSION: Overweight and obese individuals with type 2 diabetes who stop BE appear to be just as successful at weight loss as non-binge eaters after 1 year of treatment. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00017953. SN - 1538-3636 UR - https://www.unboundmedicine.com/medline/citation/19047532/Binge_eating_and_weight_loss_outcomes_in_overweight_and_obese_individuals_with_type_2_diabetes:_results_from_the_Look_AHEAD_trial_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=linkout&amp;SEARCH=19047532.ui DB - PRIME DP - Unbound Medicine ER -