Tags

Type your tag names separated by a space and hit enter

Neuropsychiatric profiles of patients with Alzheimer's disease and vascular dementia in Taiwan.
Int J Geriatr Psychiatry. 2009 Jun; 24(6):570-7.IJ

Abstract

BACKGROUND

Previous studies have reported several conflicting findings regarding neuropsychiatric symptoms when comparing patients with Alzheimer's disease (AD) and patients with vascular dementia (VaD).

OBJECTIVES

The purpose was to: (1) compare the prevalence of neuropsychiatric symptoms among patients with AD and VaD after controlling for demographic characteristics in difference setting and (2) rank and contrast the severity the common symptoms between the two groups in north of Taiwan.

METHODS

This study was a cross-sectional comparative design. Data were collected from clinical interviews using three instruments: the Mini-Mental Status Examination (MMSE), the Clinical Dementia Rating Scale (CDR), and the Neuropsychiatric Inventory (NPI).

RESULTS

A total of 154 subjects participated in this study. The male subjects with VaD from the outpatient setting had lower NPI scores. In the OPD, the subjects with AD had more nighttime behavior than subjects with VAD. In the nursing home setting, the subjects with VaD had higher prevalence of depression, irritability, and appetite changes than subjects with AD. The subjects with AD had more euphoria and nighttime behavior than subjects with VaD. The average of total NPI scores for people with AD and VaD from the nursing home setting indicate higher scores. In the nursing home group, the VaD subjects evidenced significantly higher irritability scores than the AD subjects.

CONCLUSIONS

This was first care unit based study in north Taiwan. Our results showed the significant differences between AD and VaD groups of NPI symptoms. Understanding those differences may aid differential diagnosis of dementia subtypes and help develop proper interventions.

Authors+Show Affiliations

School of Geriatric Nursing and Care Management, College of Nursing, Taipei Medical University, Taipei, Taiwan, ROC.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19051223

Citation

Hsieh, Chia-Jung, et al. "Neuropsychiatric Profiles of Patients With Alzheimer's Disease and Vascular Dementia in Taiwan." International Journal of Geriatric Psychiatry, vol. 24, no. 6, 2009, pp. 570-7.
Hsieh CJ, Chang CC, Lin CC. Neuropsychiatric profiles of patients with Alzheimer's disease and vascular dementia in Taiwan. Int J Geriatr Psychiatry. 2009;24(6):570-7.
Hsieh, C. J., Chang, C. C., & Lin, C. C. (2009). Neuropsychiatric profiles of patients with Alzheimer's disease and vascular dementia in Taiwan. International Journal of Geriatric Psychiatry, 24(6), 570-7. https://doi.org/10.1002/gps.2156
Hsieh CJ, Chang CC, Lin CC. Neuropsychiatric Profiles of Patients With Alzheimer's Disease and Vascular Dementia in Taiwan. Int J Geriatr Psychiatry. 2009;24(6):570-7. PubMed PMID: 19051223.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neuropsychiatric profiles of patients with Alzheimer's disease and vascular dementia in Taiwan. AU - Hsieh,Chia-Jung, AU - Chang,Chia-Chi, AU - Lin,Chia-Chin, PY - 2008/12/4/pubmed PY - 2010/7/14/medline PY - 2008/12/4/entrez SP - 570 EP - 7 JF - International journal of geriatric psychiatry JO - Int J Geriatr Psychiatry VL - 24 IS - 6 N2 - BACKGROUND: Previous studies have reported several conflicting findings regarding neuropsychiatric symptoms when comparing patients with Alzheimer's disease (AD) and patients with vascular dementia (VaD). OBJECTIVES: The purpose was to: (1) compare the prevalence of neuropsychiatric symptoms among patients with AD and VaD after controlling for demographic characteristics in difference setting and (2) rank and contrast the severity the common symptoms between the two groups in north of Taiwan. METHODS: This study was a cross-sectional comparative design. Data were collected from clinical interviews using three instruments: the Mini-Mental Status Examination (MMSE), the Clinical Dementia Rating Scale (CDR), and the Neuropsychiatric Inventory (NPI). RESULTS: A total of 154 subjects participated in this study. The male subjects with VaD from the outpatient setting had lower NPI scores. In the OPD, the subjects with AD had more nighttime behavior than subjects with VAD. In the nursing home setting, the subjects with VaD had higher prevalence of depression, irritability, and appetite changes than subjects with AD. The subjects with AD had more euphoria and nighttime behavior than subjects with VaD. The average of total NPI scores for people with AD and VaD from the nursing home setting indicate higher scores. In the nursing home group, the VaD subjects evidenced significantly higher irritability scores than the AD subjects. CONCLUSIONS: This was first care unit based study in north Taiwan. Our results showed the significant differences between AD and VaD groups of NPI symptoms. Understanding those differences may aid differential diagnosis of dementia subtypes and help develop proper interventions. SN - 1099-1166 UR - https://www.unboundmedicine.com/medline/citation/19051223/Neuropsychiatric_profiles_of_patients_with_Alzheimer's_disease_and_vascular_dementia_in_Taiwan_ L2 - https://doi.org/10.1002/gps.2156 DB - PRIME DP - Unbound Medicine ER -